Zobrazeno 1 - 10
of 16
pro vyhledávání: '"James H. Girsch"'
Autor:
Carli M. Stewart, Elizabeth L. Siegler, R. Leo Sakemura, Michelle J. Cox, Truc Huynh, Brooke Kimball, Long Mai, Ismail Can, Claudia Manriquez Roman, Kun Yun, Olivia Sirpilla, James H. Girsch, Ekene Ogbodo, Wazim Mohammed Ismail, Alexandre Gaspar-Maia, Justin Budka, Jenny Kim, Nathalie Scholler, Mike Mattie, Simone Filosto, Saad S. Kenderian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Durable response to chimeric antigen receptor T (CART) cell therapy remains limited in part due to CART cell exhaustion. Here, we investigate the regulation of CART cell exhaustion with three independent approaches including: a genome-wide C
Externí odkaz:
https://doaj.org/article/9385e305f428439ba7536b1503dee2fa
Autor:
Shuto Negishi, James H. Girsch, Elizabeth L. Siegler, Evandro D. Bezerra, Kotaro Miyao, R. Leo Sakemura
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2024)
Clinical trials of anti-CD19 chimeric antigen receptor T (CART19) cell therapy have shown high overall response rates in patients with relapsed/refractory B-cell malignancies. CART19 cell therapy has been approved by the US Food and Drug Administrati
Externí odkaz:
https://doaj.org/article/57f5450f57a94f5d869f86b22d6a122f
Autor:
James H. Girsch, Maria C. Mejia Plazas, Amanda Olivier, Mohamed Farah, Dawn Littlefield, Supriya Behl, Sohan Punia, Reona Sakemura, Jack R. Hemsath, Andrew Norgan, Elizabeth A. L. Enninga, Erica L. Johnson, Rana Chakraborty
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
In humans, the hemochorial placenta is a unique temporary organ that forms during pregnancy to support fetal development, gaseous exchange, delivery of nutrition, removal of waste products, and provides immune protection, while maintaining tolerance
Externí odkaz:
https://doaj.org/article/9808515080ff4732be16966cb58d4e6f
Autor:
Reona Leo Sakemura, Claudia Manriquez-Roman, Paulina Horvei, Michelle J. Cox, Truc Huynh, James H. Girsch, Olivia Sirpilla, Kun Yun, Carli M. Stewart, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Kristina Ilieva-Babinsky, Christian Augsberger, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S. Nowakowski, Elizabeth L. Siegler, Saad S. Kenderian
Publikováno v:
Blood. 140:2362-2364
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52e5762aeb2367080e6b9c8c43808cc6
https://doi.org/10.1182/blood-2022-158273
https://doi.org/10.1182/blood-2022-158273
Autor:
Olivia Sirpilla, R. Leo Sakemura, Mehrdad Hefazi, Truc N Huynh, James H. Girsch, Ismail Can, Kun Yun, Claudia Manriquez Roman, Carli M. Stewart, Ekene J. Ogbodo, Elizabeth L. Siegler, Saad S. Kenderian
Publikováno v:
Transplantation and Cellular Therapy. 29:S57-S58
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0918312bb64c6fab43e65d8ed770d263
https://doi.org/10.1016/s2666-6367(23)00137-9
https://doi.org/10.1016/s2666-6367(23)00137-9
Autor:
R. Leo Sakemura, Claudia Manriquez Roman, Paulina Horvei, Truc N Huynh, James H. Girsch, Olivia Sirpilla, Kun Yun, Carli M. Stewart, Ismail Can, Ekene J. Ogbodo, Mohamad M. Adada, Lionel Aurelien Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Kristina Ilieva-Babinsky, Christian Augsberger, Maria Patra-Kneuer, Christina Heitmüller, Stefan Steidl, Sameer A. Parikh, Wei Ding, Neil E. Kay, Grzegorz S Nowakowski, Elizabeth L. Siegler, Saad S. Kenderian
Publikováno v:
Transplantation and Cellular Therapy. 29:S11-S12
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c0661eb13a892386d5b87b8bb8cfb8e
https://doi.org/10.1016/s2666-6367(23)00082-9
https://doi.org/10.1016/s2666-6367(23)00082-9
Autor:
Carli Stewart, Michelle J. Cox, Reona Sakemura, Ekene J. Ogbodo, Ismail Can, Claudia Manriquez Roman, Kun Yun, Olivia Sirpilla, James H. Girsch, Truc Huynh, Elizabeth L. Siegler, Jenny J. Kim, Mike Mattie, Nathalie Scholler, Simone Filosto, Saad S. Kenderian
Publikováno v:
Cancer Research. 83:1153-1153
While chimeric antigen receptor T-cell therapy targeting CD19 (CART19) has shown remarkable success in the treatment of hematological malignancies, the durable response rates remain approximately 40% and there are limited solutions for CART cell ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79fa71ea437d2112e4e562465ad57606
https://doi.org/10.1158/1538-7445.am2023-1153
https://doi.org/10.1158/1538-7445.am2023-1153
Autor:
Ismail Can, Reona Leo Sakemura, Claudia Manriquez-Roman, Olivia Sirpilla, Carli M. Stewart, Kun Yun, Michelle J. Cox, Truc Huynh, James H. Girsch, Ekene J. Ogbodo, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Justin C. Boysen, Elizabeth L. Siegler, Atakan Ekiz, Saad S. Kenderian, Neil E. Kay
Publikováno v:
Blood. 140:8600-8601
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d8d1482c447148e84c30653e0df530c
https://doi.org/10.1182/blood-2022-163446
https://doi.org/10.1182/blood-2022-163446
Autor:
Carli M. Stewart, Michelle J. Cox, Reona Leo Sakemura, Ekene J. Ogbodo, Ismail Can, Claudia Manriquez-Roman, Kun Yun, Olivia Sirpilla, James H. Girsch, Truc Huynh, Elizabeth L. Siegler, Jenny J Kim, Mike Mattie, Nathalie Scholler, Simone Filosto, Saad S. Kenderian
Publikováno v:
Blood. 140:4536-4537
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::066e2fc6165eda6cac9cfb7275b76c81
https://doi.org/10.1182/blood-2022-160219
https://doi.org/10.1182/blood-2022-160219
Autor:
Kun Yun, Reona Leo Sakemura, Michelle J. Cox, Truc Huynh, Claudia Manriquez-Roman, Olivia Sirpilla, Carli M. Stewart, James H. Girsch, Ekene J. Ogbodo, Ismail Can, Brooke Kimball, Lionel A. Kankeu Fonkoua, Mehrdad Hefazi, Michael W. Ruff, Elizabeth L. Siegler, Mike Mattie, Sao-Mai Nguyen-Mau, Simone Filosto, Saad S. Kenderian
Publikováno v:
Blood. 140:10263-10264
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39b6b977a57a19ab7a91a43c880d5447
https://doi.org/10.1182/blood-2022-164706
https://doi.org/10.1182/blood-2022-164706