Výsledky vyhledávání - "James H. Fox"

Akademický článek

Exercise reduces the anxiogenic effects of meta-chlorophenylpiperazine: The role of 5-HT2C receptors in the bed nucleus of the stria terminalis

Autor: James H. Fox, Melissa N. Boucher, Khalil S. Abedrabbo, Brendan D. Hare, Bethany A. Grimmig, William A. Falls, Sayamwong E. Hammack

Publikováno v: Frontiers in Synaptic Neuroscience, Vol 14 (2023)

IntroductionTwo weeks of voluntary exercise in group-housed mice produces a reduction in anxiety-like behaviors across a number of different measures, including a reduction in the anxiety levels typically produced by the anxiogenic serotonergic drug

Externí odkaz: https://doaj.org/article/d5b40d210e674bb09f367eced780b148

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Akademický článek

Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior

Autor: James H Fox, Christopher A Lowry

Publikováno v: Frontiers in Neuroscience, Vol 7 (2013)

Corticotropin-releasing factor (CRF) is a 41-amino acid neuropeptide that is involved in stress-related physiology and behavior, including control of the hypothalamic-pituitary-adrenal (HPA) axis. Members of the CRF family of neuropeptides, including

Externí odkaz: https://doaj.org/article/bb5590649ddd4c6ea62f046ee0f1cc87

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Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm

Autor: James E. Hassell, Philip H. Siebler, Mathew R. Arnold, Christopher A. Lowry, Christopher J. Brazell, Heidi E.W. Day, Tessa M. Smith, James H. Fox, Andrew K. Lamb, Alexander A. Outzen, Emma M. Simmerman, David G. Smith, Kaley S. Holmes

Publikováno v: Brain, Behavior, and Immunity. 66:70-84

The hygiene hypothesis or "Old Friends" hypothesis proposes that inflammatory diseases are increasing in modern urban societies, due in part to reduced exposure to microorganisms that drive immunoregulatory circuits, and a failure to terminate inappr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac294d88c309138de180e989ba9f31ee
https://doi.org/10.1016/j.bbi.2017.08.014

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Acute engagement of Gq-mediated signaling in the bed nucleus of the stria terminalis induces anxiety-like behavior

Autor: Jessica M. McKlveen, K Duffy, James H. Fox, Sayamwong E. Hammack, Dipanwita Pati, Jeffrey F. DiBerto, Thomas L. Kash, S T Magness, Gregory J. Tipton, Christopher M. Mazzone, Yasmin L. Hurd, Zoe A. McElligott, William A. Falls, Michael Michaelides, C Anderson, J A Hardaway

Publikováno v: Molecular Psychiatry. 23:143-153

The bed nucleus of the stria terminalis (BNST) is a brain region important for regulating anxiety-related behavior in both humans and rodents. Here we used a chemogenetic strategy to investigate how engagement of G protein-coupled receptor (GPCR) sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7c77a68e2dc09fffcc64938470fa2a78
https://doi.org/10.1038/mp.2016.218

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Treatment with a heat-killed preparation of Mycobacterium vaccae after fear conditioning enhances fear extinction in the fear-potentiated startle paradigm

Autor: Chloé A. Gates, James E. Hassell, Tessa M. Smith, Philip H. Siebler, Margaret W. Lieb, Kelsey M. Loupy, Dominic Schmidt, Kadi T. Nguyen, Kaley S. Holmes, Emma J. Spratt, Mathew R. Arnold, James H. Fox, Maike Erber, Christopher A. Lowry, K’Loni S. Schnabel

Publikováno v: Brain Behav Immun

The hygiene hypothesis or “Old Friends” hypothesis proposes that inflammatory diseases are increasing in modern urban societies, due in part to reduced exposure to microorganisms that drive immunoregulatory circuits and a failure to terminate ina

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::827052e1c629e42c5b82368fc80e78a5
https://europepmc.org/articles/PMC6754802/

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The Microbiota, Immunoregulation, and Mental Health: Implications for Public Health

Publikováno v: Current environmental health reports, vol 3, iss 3

The hygiene or "Old Friends" hypothesis proposes that the epidemic of inflammatory disease in modern urban societies stems at least in part from reduced exposure to microbes that normally prime mammalian immunoregulatory circuits and suppress inappro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd1a9f6f79694ee9aa252dfabcd6b47d
https://doi.org/10.1007/s40572-016-0100-5

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Evidence that preimmunization with a heat-killed preparation of Mycobacterium vaccae reduces corticotropin-releasing hormone mRNA expression in the extended amygdala in a fear-potentiated startle paradigm

Autor: James E. Hassell, Heidi E.W. Day, Margaret W. Lieb, James H. Fox, Kristin E. Cler, Philip H. Siebler, Mathew R. Arnold, Sylvana I.S.R. Noronha, Lauren N. Milton, Christopher A. Lowry, Dominic Schmidt, Kelsey M. Loupy

Publikováno v: Brain, behavior, and immunity. 77

Posttraumatic stress disorder (PTSD) is a trauma and stressor-related disorder that is characterized by dysregulation of glucocorticoid signaling, chronic low-grade inflammation, and impairment in the ability to extinguish learned fear. Corticotropin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d931f97a5b19839f155f6dd6dba52e11
https://pubmed.ncbi.nlm.nih.gov/30797961

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Immunization with a heat-killed preparation of the environmental bacterium Mycobacterium vaccae promotes stress resilience in mice

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, vol 113, iss 22

The prevalence of inflammatory diseases is increasing in modern urban societies. Inflammation increases risk of stress-related pathology; consequently, immunoregulatory or antiinflammatory approaches may protect against negative stress-related outcom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48630380434c84a5dccd079b4a244526
https://escholarship.org/uc/item/8jx3r6ns

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Voluntary exercise improves both learning and consolidation of cued conditioned fear in C57 mice

Autor: William A. Falls, Christina M. MacAulay, James H. Fox

Publikováno v: Behavioural Brain Research. 207:321-331

Exercise is associated with improved cognitive function in humans as well as improved learning across a range of tasks in rodents. Although these studies provide a strong link between exercise and learning, to date studies have largely focused on tas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ef984ca5d427a208f2f20d13fdda47e
https://doi.org/10.1016/j.bbr.2009.10.016

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