Zobrazeno 1 - 10
of 209
pro vyhledávání: '"James H-C. Wang"'
Publikováno v:
Foot & Ankle Orthopaedics, Vol 8 (2023)
Category: Basic Sciences/Biologics; Diabetes Introduction/Purpose: Diabetes mellitus is a chronic metabolic disease that leads to serious complications including bone health and wound healing. Bone fractures commonly occur in diabetic patients, and a
Externí odkaz:
https://doaj.org/article/3373e96ca7034bb192c17fce7f5b03fd
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1739 (2023)
Tendon injuries, while prevalent, present significant challenges regarding their structural and functional restoration. Utilizing alpha-smooth muscle actin (α-SMA)-Ai9-scleraxis (Scx)-green fluorescent protein (GFP) transgenic mice, which exhibit bo
Externí odkaz:
https://doaj.org/article/49c1c07c9dab4c29a623512e1b0b829a
Publikováno v:
Journal of Orthopaedic Translation, Vol 15, Iss , Pp 9-20 (2018)
Ultrasound elastography (UE) and ultrasound tissue characterisation (UTC) are two newer modes of ultrasound (US) which have begun to attract scientific interests as ways to improve tendon characterisation. These modes of US show early promise in impr
Externí odkaz:
https://doaj.org/article/f79528f155dd4d90bef0d9e7ce620c72
Tendon Stem/Progenitor Cells and Their Interactions with Extracellular Matrix and Mechanical Loading
Publikováno v:
Stem Cells International, Vol 2019 (2019)
Tendons are unique connective tissues in the sense that their biological properties are largely determined by their tendon-specific stem cells, extracellular matrix (ECM) surrounding the stem cells, mechanical loading conditions placed on the tendon,
Externí odkaz:
https://doaj.org/article/5ecb1ea4c7e342ab875f59d25cf572c5
Autor:
Jianying Zhang PhD, Nigel Zheng PhD, Ting Yuan, Yiqin Zhou Zhou MD, Saimanoj R. Narava, MaCalus V. Hogan MD, James H-C. Wang PhD
Publikováno v:
Foot & Ankle Orthopaedics, Vol 1 (2016)
Category: Basic Sciences/Biologics Introduction/Purpose: Tendon-bone junction (TBJ) injuries are very common and optimal treatment modalities are lacking. TBJ injuries often heal without formation of the fibrocartilage transition zone increasing the
Externí odkaz:
https://doaj.org/article/06b08aa19dbc41878ca141f672c4b1d3
Autor:
Yiqin Zhou Zhou MD, Jinsong Yang, Saimanoj R. Narava, Guangyi Zhao BS, Jianying Zhang PhD, MaCalus V. Hogan MD, James H-C. Wang PhD
Publikováno v:
Foot & Ankle Orthopaedics, Vol 1 (2016)
Category: Basic Sciences/Biologics Introduction/Purpose: The normal tendon-bone junction (TBJ) is a strong structure protected by the fibrocartilage transition zone. This allows a gradual transition of mechanical forces between tendon and bone, thus
Externí odkaz:
https://doaj.org/article/f30ecc83664b4a25931f0998bf6a7f74
Autor:
Jianying Zhang PhD, Jorge L. Rocha BA, Justin H. Hicks Biomedical Engineering, Melissa McLane, James H-C. Wang PhD, MaCalus V. Hogan MD
Publikováno v:
Foot & Ankle Orthopaedics, Vol 1 (2016)
Category: Basic Sciences/Biologics Introduction/Purpose: Tendon injuries occur frequently and cost billions of health care dollars annually. Recently, there has been an increase in the use of platelet-rich plasma (PRP) to treat tendon injuries. Howev
Externí odkaz:
https://doaj.org/article/6210277cc6674f689319d55346179f35
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Despite the importance of mechanical loading in tendon homeostasis and pathophysiology, the molecular responses involved in the mechanotransduction in tendon cells remain unclear. In this study, we found that in vitro mechanical loading activated the
Externí odkaz:
https://doaj.org/article/271b6cae94d34a93a05adfed06109747
Autor:
Jianying Zhang, Daibang Nie, Kelly Williamson, Arthur McDowell, MaCalus V Hogan, James H-C Wang
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0242640 (2020)
To examine the differential mechanobiological responses of specific resident tendon cells, we developed an in vivo model of whole-body irradiation followed by injection of either tendon stem/progenitor cells (TSCs) expressing green fluorescent protei
Externí odkaz:
https://doaj.org/article/f027a7688b9e4f62a33f2640a7575faf
Publikováno v:
Journal of Orthopaedic Research. 41:1162-1176
This study aimed to characterize aging-induced tendinopathy in mouse Achilles tendon and also to assess the treatment effects of metformin (Met) on aging tendon. We showed that compared to young tendon, aging tendon was in an inflammatory and senesce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c671c5437e873f8c61c833a23384bf9
https://doi.org/10.1002/jor.25470
https://doi.org/10.1002/jor.25470