Zobrazeno 1 - 10
of 322
pro vyhledávání: '"James H Naismith"'
Autor:
Maud Dumoux, Thomas Glen, Jake LR Smith, Elaine ML Ho, Luis MA Perdigão, Avery Pennington, Sven Klumpe, Neville BY Yee, David Andrew Farmer, Pui YA Lai, William Bowles, Ron Kelley, Jürgen M Plitzko, Liang Wu, Mark Basham, Daniel K Clare, C Alistair Siebert, Michele C Darrow, James H Naismith, Michael Grange
Publikováno v:
eLife, Vol 12 (2023)
Serial focussed ion beam scanning electron microscopy (FIB/SEM) enables imaging and assessment of subcellular structures on the mesoscale (10 nm to 10 µm). When applied to vitrified samples, serial FIB/SEM is also a means to target specific structur
Externí odkaz:
https://doaj.org/article/fbc6e73bd5344bb9801714368bad32dd
Autor:
Lucile Moynié, Ilaria Serra, Mariano A Scorciapino, Emilia Oueis, Malcolm GP Page, Matteo Ceccarelli, James H Naismith
Publikováno v:
eLife, Vol 7 (2018)
New strategies are urgently required to develop antibiotics. The siderophore uptake system has attracted considerable attention, but rational design of siderophore antibiotic conjugates requires knowledge of recognition by the cognate outer-membrane
Externí odkaz:
https://doaj.org/article/75667c88bc5a46d98e1880560aea680d
Autor:
Michal Barski, Benjamin Brennan, Ona K Miller, Jane A Potter, Swetha Vijayakrishnan, David Bhella, James H Naismith, Richard M Elliott, Ulrich Schwarz-Linek
Publikováno v:
eLife, Vol 6 (2017)
Rift Valley fever phlebovirus (RVFV) is a clinically and economically important pathogen increasingly likely to cause widespread epidemics. RVFV virulence depends on the interferon antagonist non-structural protein (NSs), which remains poorly charact
Externí odkaz:
https://doaj.org/article/19588a1c3b574d549ea54582638575ab
Publikováno v:
Frontiers in Chemical Biology, Vol 3 (2024)
Remarkable progress has been made to elucidate the structural and mechanistic enzymology of the biosynthetic pathways that give rise to naturally occurring C-nucleosides. These compounds are generally cytotoxic and exhibit interesting antiviral, anti
Externí odkaz:
https://doaj.org/article/1748ac8446a54b6684e682150a37a2c0
Autor:
Katy Cornish, Jiandong Huo, Luke Jones, Parul Sharma, Joseph W. Thrush, Sahar Abdelkarim, Anja Kipar, Siva Ramadurai, Miriam Weckener, Halina Mikolajek, Sai Liu, Imogen Buckle, Eleanor Bentley, Adam Kirby, Ximeng Han, Stephen M. Laidlaw, Michelle Hill, Lauren Eyssen, Chelsea Norman, Audrey Le Bas, John Clarke, William James, James P. Stewart, Miles Carroll, James H. Naismith, Raymond J. Owens
Publikováno v:
Open Biology, Vol 14, Iss 6 (2024)
The Omicron strains of SARS-CoV-2 pose a significant challenge to the development of effective antibody-based treatments as immune evasion has compromised most available immune therapeutics. Therefore, in the ‘arms race’ with the virus, there is
Externí odkaz:
https://doaj.org/article/724360808c1547398a8abe34b3a38c53
The respiratory arsenite oxidase: structure and the role of residues surrounding the rieske cluster.
Autor:
Thomas P Warelow, Muse Oke, Barbara Schoepp-Cothenet, Jan U Dahl, Nicole Bruselat, Ganesh N Sivalingam, Silke Leimkühler, Konstantinos Thalassinos, Ulrike Kappler, James H Naismith, Joanne M Santini
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72535 (2013)
The arsenite oxidase (Aio) from the facultative autotrophic Alphaproteobacterium Rhizobium sp. NT-26 is a bioenergetic enzyme involved in the oxidation of arsenite to arsenate. The enzyme from the distantly related heterotroph, Alcaligenes faecalis,
Externí odkaz:
https://doaj.org/article/080c252a643540bda2f9abc0330de010
Autor:
Hubing Lou, Min Chen, Susan S Black, Simon R Bushell, Matteo Ceccarelli, Tivadar Mach, Konstantinos Beis, Alison S Low, Victoria A Bamford, Ian R Booth, Hagan Bayley, James H Naismith
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25825 (2011)
Antibiotic-resistant bacteria, particularly gram negative species, present significant health care challenges. The permeation of antibiotics through the outer membrane is largely effected by the porin superfamily, changes in which contribute to antib
Externí odkaz:
https://doaj.org/article/711ecda7b47d4ed3a5c1f9ee4d31e766
Autor:
James M. Parkhurst, Adam D. Crawshaw, C. Alistair Siebert, Maud Dumoux, C. David Owen, Pedro Nunes, David Waterman, Thomas Glen, David I. Stuart, James H. Naismith, Gwyndaf Evans
Publikováno v:
IUCrJ. 10:270-287
Three-dimensional electron diffraction (3DED) from nanocrystals of biological macromolecules requires the use of very small crystals. These are typically less than 300 nm-thick in the direction of the electron beam due to the strong interaction betwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88efcf9b6518ebcf7aa9110ee82ceec3
https://doi.org/10.1107/s2052252523001902
https://doi.org/10.1107/s2052252523001902
Autor:
Miriam Weckener, Laura S. Woodward, Bradley R. Clarke, Huanting Liu, Philip N. Ward, Audrey Le Bas, David Bhella, Chris Whitfield, James H. Naismith
Publikováno v:
Open Biology. 13
The enterobacterial common antigen (ECA) is a carbohydrate polymer that is associated with the cell envelope in the Enterobacteriaceae . ECA contains a repeating trisaccharide which is polymerized by WzyE, a member of the Wzy membrane protein polymer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38ac88a49827fe0868aae51b51da9c0d
https://doi.org/10.1098/rsob.220373
https://doi.org/10.1098/rsob.220373
Autor:
Maud Dumoux, Thomas Glen, Jake LR Smith, Elaine ML Ho, Luis MA Perdigão, Avery Pennington, Sven Klumpe, Neville BY Yee, David Andrew Farmer, Pui YA Lai, William Bowles, Ron Kelley, Jürgen M Plitzko, Liang Wu, Mark Basham, Daniel K Clare, C Alistair Siebert, Michele C Darrow, James H Naismith, Michael Grange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d771b0ab21da6c07ba6e75f1abff440
https://doi.org/10.7554/elife.83623.sa2
https://doi.org/10.7554/elife.83623.sa2
