Zobrazeno 1 - 10
of 126
pro vyhledávání: '"James H Eubanks"'
Autor:
Carl J Fisher, Carolyn Niu, Warren Foltz, Yonghong Chen, Elena Sidorova-Darmos, James H Eubanks, Lothar Lilge
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181654 (2017)
Malignant gliomas are highly invasive, difficult to treat, and account for 2% of cancer deaths worldwide. Glioblastoma Multiforme (GBM) comprises the most common and aggressive intracranial tumor. The study hypothesis is to investigate the modificati
Externí odkaz:
https://doaj.org/article/577786159afc4c8dba1873a8f93c8969
Autor:
Justin Wang, Chiping Wu, Jessie Peng, Nisarg Patel, Yayi Huang, Xiaoxing Gao, Salman Aljarallah, James H Eubanks, Robert McDonald, Liang Zhang
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144113 (2015)
Aging is associated with an increased risk of seizures/epilepsy. Stroke (ischemic or hemorrhagic) and cardiac arrest related brain injury are two major causative factors for seizure development in this patient population. With either etiology, seizur
Externí odkaz:
https://doaj.org/article/c3681204a6544ee987399fa5daeed716
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e91148 (2014)
Rett syndrome is a severe pediatric neurological disorder caused by loss of function mutations within the gene encoding methyl CpG-binding protein 2 (MeCP2). Although MeCP2 is expressed near ubiquitously, the primary pathophysiology of Rett syndrome
Externí odkaz:
https://doaj.org/article/0c5ad462eb6b49f882a2a4dfdc3cd393
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35396 (2012)
Mutations in the X-linked gene encoding Methyl-CpG-binding protein 2 (MECP2) have been associated with neurodevelopmental and neuropsychiatric disorders including Rett Syndrome, X-linked mental retardation syndrome, severe neonatal encephalopathy, an
Externí odkaz:
https://doaj.org/article/8477ac22dc5e4fe798a8a1ae36100477
Publikováno v:
Frontiers in Genetics, Vol 11 (2021)
Epigenetic processes are critical for governing the complex spatiotemporal patterns of gene expression in neurodevelopment. One such mechanism is the dynamic network of post-translational histone modifications that facilitate recruitment of transcrip
Externí odkaz:
https://doaj.org/article/a992711b21ac4d71b43ab4231feb1bc7
Autor:
Jacqueline A. Gleave, Lindsay R. Arathoon, Dennison Trinh, Kristin E. Lizal, Nicolas Giguère, James H.M. Barber, Zainab Najarali, M. Hassan Khan, Sherri L. Thiele, Mahin S. Semmen, James B. Koprich, Jonathan M. Brotchie, James H. Eubanks, Louis-Eric Trudeau, Joanne E. Nash
Publikováno v:
Neurobiology of Disease, Vol 106, Iss , Pp 133-146 (2017)
Parkinson's disease (PD) is a neurodegenerative movement disorder, which affects approximately 1–2% of the population over 60 years of age. Current treatments for PD are symptomatic, and the pathology of the disease continues to progresses over tim
Externí odkaz:
https://doaj.org/article/62237862f4484511b63bc2058c5fb394
Autor:
Jacqueline A. Gleave, Lindsay R. Arathoon, Dennison Trinh, Kristin E. Lizal, Nicolas Giguère, James E.M. Barber, Zainab Najarali, M. Hassan Khan, Sherri L. Thiele, Mahin S. Semmen, James B. Koprich, Jonathan M. Brotchie, James H. Eubanks, Louis-Eric Trudeau, Joanne E. Nash
Publikováno v:
Neurobiology of Disease, Vol 116, Iss , Pp 180- (2018)
Externí odkaz:
https://doaj.org/article/173a4e0c1c9e4136a985602b2f6a470d
Autor:
Lu-Yang Wang, Tian Kong, David R. Hampson, Enea Koxhioni, Yosuke Niibori, James H. Eubanks, Alexander W.M. Hooper, Shervin Gholizadeh, Jason Arsenault, Laura K. K. Pacey
Publikováno v:
Human Molecular Genetics
Several X-linked neurodevelopmental disorders including Rett syndrome, induced by mutations in the MECP2 gene, and fragile X syndrome (FXS), caused by mutations in the FMR1 gene, share autism-related features. The mRNA coding for methyl CpG binding p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5597bf9877fb975144e909fff1b7f96
https://doi.org/10.1093/hmg/ddaa226
https://doi.org/10.1093/hmg/ddaa226
Autor:
Jennifer Anne D'Cruz, Chiping Wu, Tariq Zahid, Youssef El-Hayek, Liang Zhang, James H. Eubanks
Publikováno v:
Neurobiology of Disease, Vol 38, Iss 1, Pp 8-16 (2010)
Rett syndrome is a pediatric neurological condition caused by mutations of the gene encoding the transcriptional regulator MECP2. In this study, we examined cortical and hippocampal electroencephalographic (EEG) activity in male and female MeCP2-defi
Externí odkaz:
https://doaj.org/article/c9969afcabc1462788eff4c90f0a116c
Autor:
Ying Wu, Katherine F.Y. Chan, James H. Eubanks, C. Guin Ting Wong, Miguel A. Cortez, Liqing Shen, Chun Che Liu, Jose Perez Velazquez, Yu Tian Wang, Zhengping Jia, O. Carter Snead, III
Publikováno v:
Neurobiology of Disease, Vol 26, Iss 2, Pp 439-451 (2007)
In this study, we tested whether over-expressing the GABAB receptor R1a subtype in transgenic mouse forebrain neurons would be sufficient to induce spontaneous absence seizures. As hypothesized, these transgenic mice develop spontaneous, recurrent, b
Externí odkaz:
https://doaj.org/article/47b8f50f869f44349b01c8a053c931a9