Zobrazeno 1 - 10
of 13
pro vyhledávání: '"James H Baraniak"'
Autor:
Yandong Zhou, Robert M Nwokonko, James H Baraniak, Mohamed Trebak, Kenneth P K Lee, Donald L Gill
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000413 (2019)
Calcium signals drive an endless array of cellular responses including secretion, contraction, transcription, cell division, and growth. The ubiquitously expressed Orai family of plasma membrane (PM) ion channels mediate Ca2+ entry signals triggered
Externí odkaz:
https://doaj.org/article/60cb9b5346a049658c3c68749a95892e
Autor:
Yandong Zhou, Michelle R. Jennette, Guolin Ma, Sarah A. Kazzaz, James H. Baraniak, Robert M. Nwokonko, Mallary L. Groff, Marcela Velasquez-Reynel, Yun Huang, Youjun Wang, Donald L. Gill
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Ca2+ signal-generation through inter-membrane junctional coupling between endoplasmic reticulum (ER) STIM proteins and plasma membrane (PM) Orai channels, remains a vital but undefined mechanism. We identify two unusual overlapping Phe-His a
Externí odkaz:
https://doaj.org/article/9a0a51890d4548619de4b07244d682f4
Publikováno v:
Curr Opin Physiol
Store-operated Ca(2+) entry signals are critical for cellular regulation. This intricate signaling pathway involves coupling of proteins in two different membranes: the ER-resident Ca(2+)-sensing STIM proteins and the highly Ca(2+)-selective PM Orai
Publikováno v:
Cell Calcium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaeaefb27f05fbac4d74da5b38abb5ea
https://europepmc.org/articles/PMC8892576/
https://europepmc.org/articles/PMC8892576/
Autor:
Sarah A. Kazzaz, Jazmin M. Stenson, Mohamed Trebak, Youjun Wang, Robert M. Nwokonko, Yandong Zhou, James H. Baraniak, Abigale L. Whitsell, Donald L. Gill, Michelle R. Jennette
Publikováno v:
Cell Reports, Vol 35, Iss 13, Pp 109322-(2021)
Summary: Junctional coupling between endoplasmic reticulum (ER) Ca2+-sensor STIM proteins and plasma membrane (PM) Orai channels mediates Ca2+ signals in most cells. We reveal that PM-tethered, fluorescently tagged C-terminal M4x (fourth transmembran
Publikováno v:
Cell Res
Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f20c1e12eec91174f9109b8c87c9036
https://europepmc.org/articles/PMC8249468/
https://europepmc.org/articles/PMC8249468/
Publikováno v:
Biophysical Journal. 121:373a
Autor:
Yandong Zhou, Robert M. Nwokonko, Guolin Ma, James H. Baraniak, Jian Wang, Michelle R. Jennette, Nikolay V. Dokholyan, Yun Huang, Donald L. Gill
Publikováno v:
Biophysical Journal. 121:374a
Autor:
Michelle R. Jennette, Youjun Wang, Abigale L. Whitsell, Yandong Zhou, Robert M. Nwonkonko, Mohamed Trebak, Jazmin M. Stenson, James H. Baraniak, Sarah A. Kazzaz, Donald L. Gill
Publikováno v:
SSRN Electronic Journal.
The junctional coupling between endoplasmic reticulum (ER) Ca2+-sensor STIM proteins and plasma membrane (PM) Orai channels is a universal Ca2+ signaling pathway. Despite its importance, the crucial STIM-Orai coupling interface mediating channel gati
Autor:
James H. Baraniak, Donald L. Gill, Kenneth P K Lee, Mohamed Trebak, Yandong Zhou, Robert M. Nwokonko
Publikováno v:
PLoS Biology, Vol 17, Iss 8, p e3000413 (2019)
PLoS Biology
PLoS Biology
The Orai channel is characterized by voltage independence, low conductance, and high Ca2+ selectivity and plays an important role in Ca2+ influx through the plasma membrane (PM). How the channel is activated and promotes Ca2+ permeation is not well u