Zobrazeno 1 - 6
of 6
pro vyhledávání: '"James H, Catterson"'
Autor:
Jennifer C. Regan, Yu-Xuan Lu, Enric Ureña, Ralf L. Meilenbrock, James H. Catterson, Disna Kißler, Jenny Fröhlich, Emilie Funk, Linda Partridge
Publikováno v:
Regan, J C, Lu, Y X, Ureña, E, Meilenbrock, R L, Catterson, J H, Kißler, D, Fröhlich, J, Funk, E & Partridge, L 2022, ' Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin ', Nature Aging, vol. 2, no. 12, pp. 1145-1158 . https://doi.org/10.1038/s43587-022-00308-7
Nature Aging
Nature aging
Nature Aging
Nature aging
Pharmacological attenuation of mTOR presents a promising route for delay of age-related disease. Here we show that treatment of Drosophila with the mTOR inhibitor rapamycin extends lifespan in females, but not in males. Female-specific, age-related g
Autor:
Salomé Aspe, Miranda C. Dyson, Sebastian Judd-Mole, Magda L. Atilano, Claire S. Durrant, Linda Partridge, James H. Catterson, Mumtaz Ahmad, Lucy J. Minkley, Sofia Moura, Tara L. Spires-Jones, Nathaniel S. Woodling, Arjunan Rajasingam
Accumulation of Aβ in the brain is one of the hallmarks of Alzheimer’s disease (AD). In the adult Drosophila brain, human Aβ over-expression is toxic and leads to deterioration of climbing ability and shortened lifespan. However, it remains unkno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::362ddf95b7b011917f0cf57eceec9461
https://doi.org/10.1101/2021.08.18.456775
https://doi.org/10.1101/2021.08.18.456775
Autor:
Jessica R Ivy, Maik Drechsler, James H Catterson, Rolf Bodmer, Karen Ocorr, Achim Paululat, Paul S Hartley
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134620 (2015)
Insect nephrocytes are highly endocytic scavenger cells that represent the only invertebrate model for the study of human kidney podocytes. Despite their importance, nephrocyte development is largely uncharacterised. This work tested whether the inse
Externí odkaz:
https://doaj.org/article/0fb44840db3240c181f73952ba081bc2
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e62958 (2013)
The vertebrate Kindlins are an evolutionarily conserved family of proteins critical for integrin signalling and cell adhesion. Kindlin-2 (KIND2) is associated with intercalated discs in mice, suggesting a role in cardiac syncytium development; howeve
Externí odkaz:
https://doaj.org/article/04da238e1c374369bbed5270a7bc9a9f
Autor:
James H Catterson, Seymour Knowles-Barley, Katherine James, Margarete M S Heck, Anthony J Harmar, Paul S Hartley
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12062 (2010)
A complex relationship exists between diet and sleep but despite its impact on human health, this relationship remains uncharacterized and poorly understood. Drosophila melanogaster is an important model for the study of metabolism and behaviour, how
Externí odkaz:
https://doaj.org/article/7c69e9579d124e74b0c36c867b92d125
Autor:
James H, Catterson, Mobina, Khericha, Miranda C, Dyson, Alec J, Vincent, Rebecca, Callard, Steven M, Haveron, Arjunan, Rajasingam, Mumtaz, Ahmad, Linda, Partridge
Publikováno v:
Current Biology
Summary Intermittent fasting (IF) can improve function and health during aging in laboratory model organisms, but the mechanisms at work await elucidation. We subjected fruit flies (Drosophila melanogaster) to varying degrees of IF and found that jus