Zobrazeno 1 - 8
of 8
pro vyhledávání: '"James Greg Falls"'
Autor:
James Greg Falls, Douglas C. Wolf, Yvonne P. Dragan, Michael L. Cunnningham, Darlene Dixon, Karen A. Augustine, Syril D. Pettit, Robert C. Sills, Jay I. Goodman, Richard D. Storer, Reza J. Rasoulpour
Publikováno v:
Toxicological Sciences. 116:375-381
The International Life Sciences Institute, Health and Environmental Sciences Institute sponsored a workshop entitled "State of the Science: Evaluating Epigenetic Changes," hosted by the National Institute of Environmental Health Sciences, Research Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ab0beff31679d2572e90ae554c3f76a
https://doi.org/10.1093/toxsci/kfq133
https://doi.org/10.1093/toxsci/kfq133
Autor:
Connie A. Cummings, James Greg Falls, Nancy R. Bordelon, Richard A. Peterson, Thomas A. Brodie, Elizabeth H. Romach, Richard T. Miller, Brenda Faiola
Publikováno v:
Toxicological Sciences. 105:384-394
Therapeutic use of certain peroxisome proliferator-activated receptor (PPAR) alpha agonists (fibrates) for the treatment of dyslipidemia has infrequently been associated with the untoward side effect of myopathy. With interest in PPAR-delta as a ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe7b85eb0c631b90496aab94b750cf89
https://doi.org/10.1093/toxsci/kfn130
https://doi.org/10.1093/toxsci/kfn130
Autor:
James Greg Falls, Carie L. Kimbrough, Holly L. Jordan, Alan H. Stokes, Brian R. Berridge, Alex Rodriguez, David Krull, Lawrence Yoon, Rachel Cianciolo, John M. Cullen, David K. C. Cooper
Publikováno v:
Nephron. Experimental nephrology. 124(1-2)
Background: Tubular atrophy and interstitial fibrosis are well-recognized sequelae of chronic proteinuria; however, little is known regarding the molecular pathways activated within tubulointerstitium in chronic proteinuric nephropathies. Methods: To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f7be688aa9f34f8ab0e318fb0dca7a
https://pubmed.ncbi.nlm.nih.gov/24248038
https://pubmed.ncbi.nlm.nih.gov/24248038
Autor:
Kevin L. Dreher, Wendy G. Halpern, A. Eric Schultze, Peter Hoffmann, Nick Edmunds, Marty Sanders, Gerald Hirkaler, Dana Walker, James Greg Falls, Frank W. Sellke, Brian R. Berridge, Syril Pettit, Gary A. Gintant, James R. Turk
Publikováno v:
Regulatory toxicology and pharmacology : RTP. 65(1)
Cardiovascular (CV) safety concerns are a significant source of drug development attrition in the pharmaceutical industry today. Though current nonclinical testing paradigms have largely prevented catastrophic CV events in Phase I studies, many chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb967ad0dbddfc1b795afbaa1c0acd6
https://pubmed.ncbi.nlm.nih.gov/23044254
https://pubmed.ncbi.nlm.nih.gov/23044254
Autor:
James Greg Falls, Heidi M. Colton, Brian R. Berridge, Lawrence W. Yoon, Michael P. Quaile, Neal F. Cariello, Carie L. Kimbrough, Alan H. Stokes, Holly L. Jordan, Paul J. Novak
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 120(2)
In the clinical setting, natriuretic peptides (NPs) have proven to be reliable noninvasive markers for diagnostic, prognostic, and therapeutic monitoring of heart failure. Given their proven utility in humans, NPs are potential candidates for transla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6f57082f48518c003d827fafe706136
https://pubmed.ncbi.nlm.nih.gov/21242511
https://pubmed.ncbi.nlm.nih.gov/21242511
Autor:
Carie L. Kimbrough, Richard T. Miller, Brenda Faiola, Neil Francis Cariello, James Greg Falls, Lawrence Wonsik Yoon, Holly L. Jordan, Harlan Roger Brown, John M. Cullen
Publikováno v:
Toxicologic pathology. 38(5)
Acute toxic responses to a 50-mg/kg oral dose of 1-naphthylisothiocyanate (ANIT) were evaluated by microarray analysis of laser capture–microdissected rat biliary epithelium or hepatic parenchyma obtained 2 and 6 hours postdose. Distinct difference
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c0c44f04ee7e287a758c70d5b7ae23
https://pubmed.ncbi.nlm.nih.gov/20551477
https://pubmed.ncbi.nlm.nih.gov/20551477
Autor:
Puntipa Kwanyuen, Neal F. Cariello, Heidi M. Colton, Hong Ni, Warren Casey, Edward McNeil, James Greg Falls, Donald R Creech, G. Hamilton
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 80(1)
Peroxisome proliferation in the liver is a well-documented response that occurs in some species upon treatment with hypolipidemic drugs, such as fibrates. Typically, liver peroxisome proliferation has been estimated by direct counting via electron mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c547ab60db9b0b3a7cc6f3642c7f56
https://pubmed.ncbi.nlm.nih.gov/15084755
https://pubmed.ncbi.nlm.nih.gov/15084755
Autor:
Brenda Faiola, James Greg Falls, Richard A. Peterson, Nancy R. Bordelon, Thomas A. Brodie, Connie A. Cummings, Elizabeth H. Romach, Richard T. Miller
Publikováno v:
Toxicological Sciences; Oct2008, Vol. 105 Issue 2, p384-384, 1p