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Autor:
Nandini Sane, Paula Niksa, Jerald C. Sadoff, Alexander C. Schmidt, Stephen Karakasidis, Valerie B. Randolph, Phillip Minor, James Gombold, Kitti Neumann, Paul Duncan, James A. Richardson, Rebecca L. Sheets, Renita Johnson-Leva, John Podczasy
Publikováno v:
Vaccine. 32:2916-2926
Viral vaccines and the cell substrates used to manufacture them are subjected to tests for adventitious agents, including viruses, contaminate. Some of the compendial methods (in vivo and in vitro in cell culture) were established in the mid-20th cen