Zobrazeno 1 - 10
of 37
pro vyhledávání: '"James Galea"'
Autor:
Margaret E. Hoadley, James Galea, Navneet Singh, Sharon Hulme, David O. Ajao, Nancy Rothwell, Andrew King, Pippa Tyrrell, Stephen J. Hopkins
Publikováno v:
European Journal of Medical Research, Vol 28, Iss 1, Pp 1-12 (2023)
Abstract Background We sought to determine the extent to which cortisol suppressed innate and T cell-mediated cytokine production and whether it could be involved in reducing peripheral cytokine production following subarachnoid haemorrhage (SAH). Me
Externí odkaz:
https://doaj.org/article/662161bb7a9b41a3a4fbca781712922f
Autor:
Hiren Patel, James Galea, Giles Critchley, Nitin Mukerji, Nicholas Ross, Peter Whitfield, Jay Park, Harsh Bhatt, Megan Burns, Zoe Stone, Paul M Brennan, Jacqueline Birks, John Norris, Diederik Oliver Bulters, David Bennett, Stefan Mitrasinovic, Benjamin Fisher, Dominic Townsend, Kristin Veighey, Jonathan Downer, Rosa Sun, Andrew Bacon, Christos Michael Tolias, Justyna Ekert, Milo Hollingworth, Nikolaos Tzerakis, Ian Anderson, Edward White, Adel Helmy, Samir Matloob, Matthew Myers, Armin Nazari, Christopher Uff, Patrick Grover, Nathan McSorley, Alex Fung, Shuja Yaqub, Neeraj Kalra, James Ulrich, Rebecca Hodnett, Graham Dow, Steven Tominey, Mario Teo, Kristy Kehoe, Jeremy Cheong, Devika Rajashekar, Debayan Dasgupta, James Loan, Samuel Hall, Ajitesh Anand, Talhah Chaudri, Emmanuel Chavredakis, Nihal Gurusinghe, Gueorgui Kounin, Jash Patel, Jerome St George, Janneke van Beijum, Frederick Ewbank, Oliver Croft, Imogen Kirkpatrick, Nicole Handy, Alex Rossdeutsch, Ellie Courtney, Anthony Wiggins, Niamh Rafferty, Giannis Sokratous, Basel Taweel, Kartik Goyal, Hannah-Marie Culley, Mukul Arora, Benjamin Armstrong, David Lowes, Debra Faulkner, Ciaran Hill, Yuzhi Phuah, Olivier Sluijters, Neda Oskooee, Viraj Pamar, Tarek Elmenofi, Rebecca Legge, Srihari Deepak, Vigneshwar Veerappan, Swarnava Gupta, Sumeet Sasane, May Ting Tan, Lucie Ferguson, Antonio Bonardi, Holly Tetlow, Charlotte Dunkerley, Malvika Pandey, William Giffin, Iqbal Bin Lokman, Danielle Hurst, Daniel Ahari, Anouk Borg, Thanos Papadias, Isabella Davies, Taisha Peplowska, Mohammed Draz, Barbora Krivankova, Katy Homyer, Vivienne Evans, Attika Chaudhary, Sabrina Tengku, Eilidh Middleton, Sytske Lub, Hassan Ismahel, Michalina Wilinska, Nicola Duncan, Joanne Igoli, Ritika Sandaram, Naadir Nazar, Omar Ouaret Sorr, Fatima Camp, Tom Ferreira, Rachel Dumbrell, Ananya Muthukumar, Mohammad Anas, Lilian Nwosu, Ariadne Holmes, Ikenna Ogbu, Madalina Pasca, Veer Patel, Mustafa Dashti, Zeluleko Sibanda, Erin Hwang, Zara Adil, Vanessa Chow, Aparnu Vimal, Lauren Baldwin, Haritha Maripi, Balint Borbas, Mariyam Mujeeb
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction Unruptured intracranial aneurysms (UIA) are common in the adult population, but only a relatively small proportion will rupture. It is therefore essential to have accurate estimates of rupture risk to target treatment towards those who s
Externí odkaz:
https://doaj.org/article/3e598c06759c4d96a2005d9c166f1f8f
Autor:
James Galea, Andrew King, Kayode Ogungbenro, Omar Pathmanaban, Andy Vail, Hiren C Patel, Carlo Berzuini, Cathal Hannan, Claire O'Leary, David Brough, Megan Wright, Sharon Hulme, Stuart Allan, Luisa Bernardinelli
Publikováno v:
BMJ Open, Vol 10, Iss 9 (2020)
Externí odkaz:
https://doaj.org/article/f43adc6685484e0d92ecae74d959986f
Autor:
Michael J. D. Daniels, Jack Rivers-Auty, Tom Schilling, Nicholas G. Spencer, William Watremez, Victoria Fasolino, Sophie J. Booth, Claire S. White, Alex G. Baldwin, Sally Freeman, Raymond Wong, Clare Latta, Shi Yu, Joshua Jackson, Nicolas Fischer, Violette Koziel, Thierry Pillot, James Bagnall, Stuart M. Allan, Pawel Paszek, James Galea, Michael K. Harte, Claudia Eder, Catherine B. Lawrence, David Brough
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
NSAID-induced analgesia is typically induced by inhibition of COX enzymes. Here the authors show instead that fenamate NSAIDs inhibit the Nlrp3 inflammasome via an effect on volume-regulated anion channel function and also repurpose these drugs for t
Externí odkaz:
https://doaj.org/article/dca8360eb57c4ee588985f6c192c8a0c
Autor:
Hervé Boutin, Christian Prenant, Renaud Maroy, James Galea, Andrew D Greenhalgh, Alison Smigova, Christopher Cawthorne, Peter Julyan, Shane M Wilkinson, Samuel D Banister, Gavin Brown, Karl Herholz, Michael Kassiou, Nancy J Rothwell
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e56441 (2013)
PurposeNeuroinflammation is involved in several brain disorders and can be monitored through expression of the translocator protein 18 kDa (TSPO) on activated microglia. In recent years, several new PET radioligands for TSPO have been evaluated in di
Externí odkaz:
https://doaj.org/article/aa87008173174959b566bbd213706a64
Autor:
Frederick Ewbank, Samuel Hall, Benjamin Gaastra, Benjamin Fisher, Laura Coe, James Booker, Antony Kaldas, Ian Anderson, Giles Critchley, Mario Teo, Ahmed Toma, Rikin Trivedi, Chris Uff, Raghu Vindlacheruvu, Louise Dulhanty, Mohsen Javadpour, Daniel Walsh, James Galea, Hiren Patel, Diederik Bulters
Publikováno v:
British Journal of Neurosurgery. :1-7
Autor:
Cathal John Hannan, Abdurrahman I. Islim, Andrew F. Alalade, Andrew Bacon, Anthony Ghosh, Arthur Dalton, Ashraf Abouharb, Daniel Colman Walsh, Diederik Bulters, Edward White, Emmanouil Chavredakis, George Kounin, Giles Critchley, Graham Dow, Hiren C. Patel, Howard Brydon, Ian A. Anderson, Ioannis Fouyas, James Galea, Jerome St. George, Jarnail Bal, Krunal Patel, Mahmoud Kamel, Mario Teo, Noel Fanning, Nitin Mukerji, Patrick Grover, Patrick Mitchell, Peter C. Whitfield, Rikin Trivedi, Matthew T. Crockett, Paul Brennan, Mohsen Javadpour
Publikováno v:
Acta Neurochirurgica. 165:451-459
Due to the risk of intracranial aneurysm (IA) recurrence and the potential requirement for re-treatment following endovascular treatment (EVT), radiological follow-up of these aneurysms is necessary. There is little evidence to guide the duration and
Publikováno v:
British Journal of Neurosurgery. :1-6
Endovascular treatment (EVT) of spinal dural arteriovenous fistulae (SDAVF) has become increasingly popular given its less invasive nature. This study aims to assess radiological obliteration rates after surgery and EVT for SDAVF in a major tertiary
Autor:
Ian Galea, Soham Bandyopadhyay, Diederik Bulters, Rok Humar, Michael Hugelshofer, Dominik J. Schaer, Amr Abdulazim, Andrew F. Alalade, Sheila A. Alexander, Sergi Amaro, Sepideh Amin-Hanjani, Christopher R. Andersen, Craig Anderson, Matthew H. Anstey, József Balla, Nourou Dine Adeniran Bankole, Judith Bellapart, Hemant Bhagat, Spiros L. Blackburn, Markus Brechmann, Paul W. Buehler, Jan-Karl Burkhardt, Yujie Chen, Jeremy Cohen, P. David Cooper, Liam G. Coulthard, Elisa Cuadrado-Godia, Joan Dalton, Anthony Delaney, Sylvain Doré, Jonathan Downer, Justin Dye, Isabel Fernandez-Perez, Oliver Flower, Béla Fülesdi, Ben Gaastra, Thomas Gaberel, James Galea, Gbetoho Fortuné Gankpe, Patrick Garland, Thomas Gentinetta, Magnus Gram, Jonas Heilskov Graversen, Patrick J. Grover, Daniel Guisado-Alonso, David Hasan, Adel Helmy, Julius Höhne, Isabel Charlotte Hostettler, Ajay Prasad Hrishi, Koji Iihara, David C. Irwin, Kiran Jangra, Aruma Jiménez-O’Shanahan, Richard F. Keep, Matthew Koch, Miikka Korja, Munish Kumar, Laura Llull, James JM Loan, Miguel Ángel Lopez-Gonzalez, R. Loch Macdonald, Shalvi Mahajan, Joan Martí-Fàbregas, Jose Medina-Suárez, Soren Moestrup, John More, Eghosa Morgan, Radhakrishnan Muthuchellappan, Paul Nyquist, Coralia Sosa Pérez, Promod Pillai, Nikolaus Plesnila, Jose Javier Provencio, Eamon Raith, Anna Ramos-Pachón, Scott B. Raymond, Luca Regli, Ynte Marije Ruigrok, Poonam Saharan, Edgar A. Samaniego, Gerrit Alexander Schubert, Ian Seppelt, Kamath Sriganesh, Jose I. Suarez, Jonathon Taylor, Nicole A. Terpolilli, Fernando D. Testai, Emanuela Tolosano, Ahmed K. Toma, Anderson Chun On Tsang, Andrew A. Udy, Florence Vallelian, Mariana Vargas-Caballero, Gregory M Vercellotti, Mervyn D.I. Vergouwen, Michaela Waak, Hannah Warming, Peter C. Whitfield, George Kwok-chu Wong, Jason Wright, Adrian W. Zuercher
Aneurysmal subarachnoid hemorrhage (aSAH) is a devastating form of stroke frequently affecting young to middle-aged adults, with an unmet need to improve outcome. This special report focusses on the development of intrathecal haptoglobin supplementat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10a25129170eddadbded8b4eb4222689
Autor:
Krunal Patel, Andrew D Bacon, Mahmoud Kamel, Diederik Bulters, Pawan Minhas, Nitin Mukerji, AK Toma, Peter C. Whitfield, Anna Visca, Graham Dow, James Galea, Nihal T. Gurusinghe, Anuj Bahl, Rikin A. Trivedi, David Mowle, Mario Teo, Edward White, John Norris, Ioannis P. Fouyas, Hiren C. Patel, Patrick Mitchell, Ian A Anderson, Howard Brydon, Daniel C. Walsh, Chris Uff, Jerome St George, Samuel Hall, Ashraf Abouharb, Jash Patel, Anthony Ghosh, Ramesh Nair
Publikováno v:
British Journal of Neurosurgery. 37:163-169
Objective Unruptured intracranial aneurysms (UIA) are common. For many the treatment risks outweigh their risk of subarachnoid haemorrhage and patients undergo surveillance imaging. There is little data to inform if and how to monitor UIAs resulting