Zobrazeno 1 - 10
of 28
pro vyhledávání: '"James G. Henkel"'
Autor:
Jeffrey T. Hane, James G. Henkel
Publikováno v:
ChemInform. 22
A synthesis of mono- and disubstituted 2-azaadamantanes with control of substituent stereochemistry has been developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61b1111a22c2499c70a5046be9251c24
https://doi.org/10.1002/chin.199123160
https://doi.org/10.1002/chin.199123160
Autor:
James G. Henkel, Jeffrey T. Hane
Publikováno v:
Tetrahedron Letters. 31:2949-2952
A synthesis of mono- and disubstituted 2-azaadamantanes with control of substituent stereochemistry has been developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::077cb6a1b968da294c0f1adf2f0fd84c
https://doi.org/10.1016/s0040-4039(00)88995-9
https://doi.org/10.1016/s0040-4039(00)88995-9
Autor:
James G. Henkel
Publikováno v:
Journal of molecular graphics. 9(1)
Among the most difficult aspects of medicinal chemistry and biochemistry for the student to master are the three-dimensional (3D) nature of drugs and bio-organic substances and the interaction of these substances with 3D targets. Compounding this pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f735f246e9f800232c7f1ba7bfebc950
https://pubmed.ncbi.nlm.nih.gov/1708280
https://pubmed.ncbi.nlm.nih.gov/1708280
Autor:
James G. Henkel, Joni H. Spector
Publikováno v:
The Journal of Organic Chemistry. 48:3657-3661
On prepare les cetones du titre a partir de l'acide bicyclo [3.3.1] nonene-6 carboxylique-3. On etudie l'epimerisation en milieu acide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4ee33df7da8766d77bae10b6704a9af
https://doi.org/10.1021/jo00169a008
https://doi.org/10.1021/jo00169a008
Publikováno v:
Journal of Pharmacy and Pharmacology. 38:353-356
Alkyl substitution on the nitrogen atom of the anti-parkinsonian drug amantadine resulted in changes in its pharmacological potency. Greater behavioural stimulation (i.e. increased motor activity) was observed following s.c. injection of several of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c13efc96aa6f5c9d7ab36612f756d345
https://doi.org/10.1111/j.2042-7158.1986.tb04586.x
https://doi.org/10.1111/j.2042-7158.1986.tb04586.x
Publikováno v:
The Journal of Organic Chemistry. 46:3483-3486
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c6a3eac9980bdb63b43e242aa059238
https://doi.org/10.1021/jo00330a020
https://doi.org/10.1021/jo00330a020
Publikováno v:
Journal of Liquid Chromatography. 5:305-312
A reverse phase paired ion HPLC procedure is described for the separation of multigram quantities of epimeric alkaloids using camphorsulfonic acid as the ion-pairing reagent.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7effca997e9e41563c663782b3598d97
https://doi.org/10.1080/01483918208069072
https://doi.org/10.1080/01483918208069072
Publikováno v:
Journal of Medicinal Chemistry. 19:6-10
Crystalline perchlorate salts of aziridinium ions derived from phenoxybenzamine and dibenamine were prepared. Both aziridinium ions were tested on the rat vas deferens and found to possess alpha-adrenergic potencies which were nearly identical with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65ada26a75ee53fc6a642a53293e3f67
https://doi.org/10.1021/jm00223a002
https://doi.org/10.1021/jm00223a002
Publikováno v:
Journal of Medicinal Chemistry. 31:1279-1282
Synthese, identification par spectre RMN, stabilite et reaction nucleophile thiirenium du [acetamido-2' methoxycarbonyl-2' ethyl]-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39c3370e083fea064c8f7e3ff4e2d8db
https://doi.org/10.1021/jm00402a003
https://doi.org/10.1021/jm00402a003
Publikováno v:
Journal of Medicinal Chemistry. 19:1308-1314
The synthesis of racemic threo- and erythro-5-methylmethadone (3a and 3b, respectively) was carried out and the solution conformation of each isomer was investigated through pKa and NMR studies. The data indicate that 3a-HCl exists exclusively in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2995b9a8bceb1988725a9fb0039fd811
https://doi.org/10.1021/jm00233a011
https://doi.org/10.1021/jm00233a011