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pro vyhledávání: '"James G. Cripps"'
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
The specific mechanisms that mediate CD4(+) T-cell-mediated liver injury have not been fully elucidated. CD4(+) invariant natural killer T (iNKT) cells are required for liver damage in some mouse models of hepatitis, while the chemokine receptors CXC
Autor:
James G. Cripps, James D. Gorham
Publikováno v:
International Immunopharmacology. 11:789-793
Myeloid derived suppressor cells (MDSC) were first described nearly two decades ago. Until recently, however, descriptions of MDSC populations were found almost exclusively in animal models of cancer or in cancer patients. Over the last few years, an
Publikováno v:
Hepatology. 52:1350-1359
T cells are the proximal agents of parenchymal liver damage in inflammatory liver diseases such as autoimmune hepatitis (AIH) and viral hepatitis. In AIH, CD4+ T cells infiltrate liver parenchyma (1) and release hepatotoxic cytokines such as IFN-γ a
Autor:
James G. Cripps, Richard T. Robinson, Heping Lin, Michael W. Milks, Jennifer L. Sargent, Jing Wang, James D. Gorham, Michael L. Whitfield
Publikováno v:
Liver International. 29:1307-1315
Background/aims BALB/c mice with a homozygous deficiency in the Tgfb1 gene are a model of fulminant autoimmune hepatitis (AIH), spontaneously and rapidly developing Th1-mediated IFN-gamma-dependent necroinflammatory liver disease. We sought to unders
Autor:
Kathryn A. English, Michael W. Milks, James D. Gorham, Richard T. Robinson, James G. Cripps, Todd Pearson, Jing Wang
Publikováno v:
The Journal of Immunology. 182:3278-3284
Fulminant inflammation in the liver is often accompanied by the accumulation of IFN-gamma-producing T cells. The BALB/c-Tgfb1(-/-) mouse exhibits extensive, spontaneously developing necroinflammation in the liver, accompanied by the accumulation of I
Autor:
James G. Cripps, Rafael Fernandez-Botran, Peteris Romanovskis, Fabian A Crespo, Arno F. Spatola
Publikováno v:
International Immunopharmacology. 5:1622-1632
Glycosaminoglycans (GAGs) located on cellular membranes and the extracellular matrix (ECM) are able to interact with chemokines and pro-inflammatory cytokines, leading to local cytokine/chemokine accumulation. The tissue-bound cytokines/chemokines fu
Autor:
James G. Cripps, Laura J. Janke, Diego A. Rodriguez, Taylor L. Brewer, Fabien Llambi, Prajwal Gurung, Giovanni Quarato, Michelle A. Kelliher, Ricardo Weinlich, Christopher P. Dillon, Thirumala-Devi Kanneganti, Yi-Nan Gong, Katherine Verbist, Douglas R. Green
Summary Receptor-interacting protein kinase (RIPK)-1 is involved in RIPK3-dependent and -independent signaling pathways leading to cell death and/or inflammation. Genetic ablation of ripk1 causes postnatal lethality, which was not prevented by deleti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b9900ee4bb0b2e3ded4572b56c533fa
https://europepmc.org/articles/PMC4068710/
https://europepmc.org/articles/PMC4068710/
Publikováno v:
The FASEB Journal. 22
Publikováno v:
Cytokine. 39:10