Zobrazeno 1 - 10
of 87
pro vyhledávání: '"James G. Bovill"'
Publikováno v:
Anaesthesia. 43:850-856
The use of a computer-assisted infusion of alfentanil, combined with 66% nitrous oxide in oxygen, for induction and maintenance of anaesthesia was evaluated in 18 elderly patients. The target alfentanil concentration for induction was varied between
Autor:
James G. Bovill
Publikováno v:
Le Praticien en Anesthésie Réanimation. 10:257-262
Publikováno v:
Anesthesia & Analgesia. 102:1789-1797
In searching for an analgesic with fewer side effects than morphine, examination of morphine's active metabolite, morphine-6-glucuronide (M6G), suggests that M6G is possibly such a drug. In contrast to morphine, M6G is not metabolized but excreted vi
Autor:
Frank H. M. Engbers, Jaap Vuyk, Erik Olofsen, Martijn J. Mertens, James G. Bovill, Anton G. L. Burm
Publikováno v:
Anesthesiology. 99:347-359
Background Remifentanil is often combined with propofol for induction and maintenance of total intravenous anesthesia. The authors studied the effect of propofol on remifentanil requirements for suppression of responses to clinically relevant stimuli
Publikováno v:
Anesthesia & Analgesia. :999-1003
UNLABELLED Anesthetics act in the spinal cord to ablate both movement and the ascending transmission of nociceptive information. We investigated whether a spinal cord action of isoflurane affected cortical activity as determined by the electroencepha
Autor:
James G. Bovill, James M. Sonner, Yi Zhang, Caroline Stabernack, Wella Abaigar, Yilei Xing, and Michael J. Laster
Publikováno v:
Anesthesia & Analgesia. :706-712
The enhancing action of propofol on gamma-amino-n-butyric acid subtype A (GABA(A)) receptors purportedly underlies its anesthetic effects. However, a recent study found that a GABA(A) antagonist did not alter the capacity of propofol to depress the r
Autor:
Annemiek de Roode, Jette A. Kuipers, F. Boer, Erik Olofsen, James G. Bovill, Anton G. L. Burm
Publikováno v:
Anesthesiology. 94:566-573
Background Inclusion of cardiac output and other physiologic parameters, in addition to or instead of, demographic variables might improve the population pharmacokinetic modeling of lidocaine. Methods Thirty-one patients were included in a population
Publikováno v:
Anesthesiology. 94:47-55
Background Recirculatory models are capable of accurately describing first-pass pharmacokinetics and the influence of cardiac output (CO), which is important for drugs with a fast onset of effect. The influence of CO on pharmacokinetic and pharmacody
Autor:
Anton G. L. Burm, A. A. Vletter, James G. Bovill, Jette A. Kuipers, F. Boer, Erik Olofsen, W. Olieman
Publikováno v:
Anesthesiology. 90:1146-1157
Background Cardiac output (CO) is likely to influence the pharmacokinetics of anesthetic drugs and should be accounted for in pharmacokinetic models. The influence of CO on the pharmacokinetic parameters of alfentanil in pigs was evaluated using comp
Publikováno v:
Anesthesiology. 87:1549-1562