Zobrazeno 1 - 10
of 356
pro vyhledávání: '"James G. Beeson"'
Autor:
Dimuthu Angage, Jill Chmielewski, Janesha C. Maddumage, Eva Hesping, Sabrina Caiazzo, Keng Heng Lai, Lee Ming Yeoh, Joseph Menassa, D. Herbert Opi, Callum Cairns, Hamsa Puthalakath, James G. Beeson, Marc Kvansakul, Justin A. Boddey, Danny W. Wilson, Robin F. Anders, Michael Foley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Apical membrane antigen-1 (AMA1) is a conserved malarial vaccine candidate essential for the formation of tight junctions with the rhoptry neck protein (RON) complex, enabling Plasmodium parasites to invade human erythrocytes, hepatocytes, a
Externí odkaz:
https://doaj.org/article/a3ab2a2651db4279a00df14289569c0e
Autor:
Jessica E. Ray, Katherine R. Dobbs, Sidney O. Ogolla, Ibrahim I. Daud, David Midem, Maxwel M. Omenda, Amy S. Nowacki, James G. Beeson, Katherine R. Sabourin, Rosemary Rochford, Arlene E. Dent
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-13 (2024)
Abstract Background Previous studies show increased morbidity in children who are HIV-exposed but uninfected (HEU) compared to children who are HIV-unexposed uninfected (HUU). We sought to evaluate the effects of prenatal HIV exposure on clinical and
Externí odkaz:
https://doaj.org/article/d1096b636f6d40f0928f7c893bde493c
Autor:
Susanne E. Mortazavi, Allan Lugaajju, Maria Nylander, Lena Danielsson, Muyideen Kolapo Tijani, James G. Beeson, Kristina E. M. Persson
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundAntibody-mediated complement fixation has previously been associated with protection against malaria in naturally acquired immunity. However, the process of early-life development of complement-fixing antibodies in infants, both in comparis
Externí odkaz:
https://doaj.org/article/8e412414d7644f6b883ac71d1acd1de6
Autor:
Donya Eghrari, Michelle J. L. Scoullar, Alyce N. Wilson, Elizabeth Peach, Arthur Elijah, Pele Melepia, Hadlee SupSup, Lisa M. Vallely, Peter M. Siba, Elissa C. Kennedy, Joshua P. Vogel, Caroline S. E. Homer, Leanne J. Robinson, Freya J. I. Fowkes, William Pomat, Brendan S. Crabb, James G. Beeson, Christopher J. Morgan
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background Globally, 2.5 million babies die in the first 28 days of life each year with most of these deaths occurring in low- and middle-income countries. Early recognition of newborn danger signs is important in prompting timely care seeki
Externí odkaz:
https://doaj.org/article/d86078a3e362468fbd21f52d73b338dc
Autor:
Gaoqian Feng, Liriye Kurtovic, Paul A. Agius, Elizabeth H. Aitken, Jahit Sacarlal, Bruce D. Wines, P. Mark Hogarth, Stephen J. Rogerson, Freya J. I. Fowkes, Carlota Dobaño, James G. Beeson
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Background RTS,S is the first malaria vaccine recommended for implementation among young children at risk. However, vaccine efficacy is modest and short-lived. Antibodies play the major role in vaccine-induced immunity, but knowledge on the
Externí odkaz:
https://doaj.org/article/eb4e7695506a424fa850de98df36ef95
Autor:
Jo-Anne Chan, Jessica R. Loughland, Lauren de la Parte, Satomi Okano, Isaac Ssewanyana, Mayimuna Nalubega, Felistas Nankya, Kenneth Musinguzi, John Rek, Emmanuel Arinaitwe, Peta Tipping, Peter Bourke, Dean Andrew, Nicholas Dooley, Arya SheelaNair, Bruce D. Wines, P. Mark Hogarth, James G. Beeson, Bryan Greenhouse, Grant Dorsey, Moses Kamya, Gunter Hartel, Gabriela Minigo, Margaret Feeney, Prasanna Jagannathan, Michelle J. Boyle
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Despite being key drivers of protective antibodies against malaria, little is known regarding the host and parasite factors that influence CD4 T-follicular helper cell and antibody development. Authors utilise samples from a study of children living
Externí odkaz:
https://doaj.org/article/cbf04ed2b51b46b3bbb1c106a6ca7595
Autor:
Alyce N. Wilson, Pele Melepia, Rose Suruka, Priscah Hezeri, Dukduk Kabiu, Delly Babona, Pinip Wapi, Naomi Spotswood, Meghan A. Bohren, Joshua P. Vogel, Angela Kelly-Hanku, Alison Morgan, James G. Beeson, Christopher Morgan, Lisa M. Vallely, Edward J. Waramin, Michelle J. L. Scoullar, Caroline S. E. Homer
Publikováno v:
BMC Pregnancy and Childbirth, Vol 22, Iss 1, Pp 1-14 (2022)
Abstract Background Renewed attention and investment is needed to improve the quality of care during the early newborn period to address preventable newborn deaths and stillbirths in Papua New Guinea (PNG). We aimed to assess early newborn care pract
Externí odkaz:
https://doaj.org/article/f201c79bff46464aa1a14b1c29ab16e1
Autor:
Bruce D. Wines, Liriye Kurtovic, Halina M. Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L. Mordant, Wen Shi Lee, Nicholas A. Gherardin, Sheila K. Patel, Gemma E. Hartley, Phillip Pymm, James P. Cooney, James G. Beeson, Dale I. Godfrey, Louise M. Burrell, Menno C. van Zelm, Adam K. Wheatley, Amy W. Chung, Wai-Hong Tham, Kanta Subbarao, Stephen J. Kent, P. Mark Hogarth
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/140fea88883d408989768880a06ffb83
Autor:
Amy L. Burns, Brad E. Sleebs, Maria Gancheva, Kimberley T. McLean, Ghizal Siddiqui, Henrietta Venter, James G. Beeson, Ryan O’Handley, Darren J. Creek, Shutao Ma, Sonja Frölich, Christopher D. Goodman, Geoffrey I. McFadden, Danny W. Wilson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
IntroductionThe spread of artemisinin resistant Plasmodium falciparum parasites is of global concern and highlights the need to identify new antimalarials for future treatments. Azithromycin, a macrolide antibiotic used clinically against malaria, ki
Externí odkaz:
https://doaj.org/article/09251fb382a0406ab2e4670017894854
Autor:
D. Herbert Opi, Michelle J. Boyle, Alistair R. D. McLean, Linda Reiling, Jo-Anne Chan, Danielle I. Stanisic, Alice Ura, Ivo Mueller, Freya J. I. Fowkes, Stephen J. Rogerson, James G. Beeson
Publikováno v:
BMC Medicine, Vol 19, Iss 1, Pp 1-16 (2021)
Abstract Background The pathogenesis of malaria in pregnancy (MiP) involves accumulation of P. falciparum-infected red blood cells (pRBCs) in the placenta, contributing to poor pregnancy outcomes. Parasite accumulation is primarily mediated by P. fal
Externí odkaz:
https://doaj.org/article/f574304c0cc84ae681465659c6a37ac1