Zobrazeno 1 - 10 of 139 pro vyhledávání: '"James G Rheinwald"'
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K Locus Effects in Gray Wolves: Experimental Assessment of TLR3 Signaling and the Gene Expression Response to Canine Distemper Virus
Autor: James G. Rheinwald, Bridgett M. vonHoldt, Robert K. Wayne, Jenny Tung, Daniel R. Stahler, William E. Lowry, Rachel A Johnston
Publikováno v: J Hered
In North American gray wolves, black coat color is dominantly inherited via a 3 base pair coding deletion in the canine beta defensin 3 (CBD103) gene. This 3 base pair deletion, called the KB allele, was introduced through hybridization with dogs and
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5cfcccc750bbdaa5653adb881667ad
https://pubmed.ncbi.nlm.nih.gov/34132805
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Experimental assessment of K locus effects on the gray wolf response to virus
Autor: Robert K. Wayne, Rachel A Johnston, Bridgett M. vonHoldt, James G. Rheinwald, William E. Lowry, Jenny Tung, Daniel R. Stahler
In North American gray wolves, black coat color is dominantly inherited via a three base pair coding deletion in the canine beta defensin 3 (CBD103) gene. This three base pair deletion, called the KB allele, was introduced through hybridization with
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ccec3d61c1c286e33cf54e6d6d8cabf3
https://doi.org/10.1101/2020.12.29.424723
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5
Akademický článek
RSK activation of translation factor eIF4B drives abnormal increases of laminin γ2 and MYC protein during neoplastic progression to squamous cell carcinoma.
Autor: Martin Degen, Patricia Barron, Easwar Natarajan, Hans R Widlund, James G Rheinwald
Publikováno v: PLoS ONE, Vol 8, Iss 10, p e78979 (2013)
Overexpression of the basement membrane protein Laminin γ2 (Lamγ2) is a feature of many epidermal and oral dysplasias and all invasive squamous cell carcinomas (SCCs). This abnormality has potential value as an immunohistochemical biomarker of prem
Externí odkaz: https://doaj.org/article/66de962471194b18bf6acd53aca87c70
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MAPK/ERK-Dependent Translation Factor Hyperactivation and Dysregulated Laminin γ2 Expression in Oral Dysplasia and Squamous Cell Carcinoma
Autor: James G. Rheinwald, Martin Degen, Patricia Barron, Easwar Natarajan, Hans R. Widlund
Publikováno v: The American Journal of Pathology. 180:2462-2478
Lesions displaying a variety of dysplastic changes precede invasive oral and epidermal squamous cell carcinoma (SCC); however, there are no histopathological criteria for either confirming or staging premalignancy. SCCs and dysplasias frequently cont
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9e3d9f04b28d892c2c4062a5ae6d079
https://doi.org/10.1016/j.ajpath.2012.02.028
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7
Graft-versus-Leukemia Antigen CML66 Elicits Coordinated B-Cell and T-Cell Immunity after Donor Lymphocyte Infusion
Autor: Jaewon Choi, Christine Canning, Wandi Zhang, Shelby A. Rogers, Edwin P. Alyea, Catherine J. Wu, Tetsuro Sasada, Wanyong Zeng, James G. Rheinwald, Vladimir Brusic, Robert J. Soiffer, Jerome Ritz, Ellis L. Reinherz
Publikováno v: Clinical Cancer Research. 16:2729-2739
Purpose: The target antigens of graft-versus-leukemia that are tumor associated are incompletely characterized. Experimental Design: We examined responses developing against CML66, an immunogenic antigen preferentially expressed in myeloid progenitor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e1ab2a21469187b42f4dd5f882623b
https://doi.org/10.1158/1078-0432.ccr-10-0415
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Immortalization eliminates a roadblock during cellular reprogramming into iPS cells
Autor: Jochen Utikal, Warakorn Kulalert, Ryan M. Walsh, Adam Khalil, Jose M. Polo, Matthias Stadtfeld, Konrad Hochedlinger, James G. Rheinwald, Nimet Maherali
Publikováno v: Nature. 460:1145-1148
The overexpression of defined transcription factors in somatic cells results in their reprogramming into induced pluripotent stem (iPS) cells1–3. The extremely low efficiency and slow kinetics of in vitro reprogramming suggest that additional rare
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdefe44cc788c280c916f1570c9c0eab
https://doi.org/10.1038/nature08285
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Co-expression of p16INK4A and Laminin 5 by Keratinocytes: A Wound-Healing Response Coupling Hypermotility with Growth Arrest that Goes Awry During Epithelial Neoplastic Progression
Autor: Easwar Natarajan, Jonathan C.R. Jones, James G. Rheinwald, John D. Omobono
Publikováno v: Journal of Investigative Dermatology Symposium Proceedings. 10(2):72-85
The replicative lifespan of human keratinocytes in culture is restricted by a telomere-unrelated induction of p16INK4A (p16) and p14ARF. We have found that, in vivo, p16 is expressed by epidermal and oral keratinocytes at the migrating fronts of heal
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5576354f69459362672b0de811f81b6
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Selective suppression of monocyte chemoattractant protein-1 expression by human papillomavirus E6 and E7 oncoproteins in human cervical epithelial and epidermal cells
Autor: John R. Basile, Christine M. Daly, Frank Rösl, Barrett J. Rollins, Deborah J. Anderson, Kerstin Kleine-Lowinski, Raina N. Fichorova, James G. Rheinwald, Karl Münger
Publikováno v: International Journal of Cancer. 107:407-415
Infection of cervical keratinocytes by high-risk HPV is involved in the etiology of cervical carcinoma. Since viral products are immunogenic, development of cancer may require suppression of immune responses directed against infected epithelial cells
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::881ae4c938690e118aead98fd831a0a5
https://doi.org/10.1002/ijc.11411
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