Zobrazeno 1 - 10
of 444
pro vyhledávání: '"James G Martin"'
Autor:
Jeffrey Downey, Erwan Pernet, François Coulombe, Benoit Allard, Isabelle Meunier, Joanna Jaworska, Salman Qureshi, Donald C Vinh, James G Martin, Philippe Joubert, Maziar Divangahi
Publikováno v:
PLoS Pathogens, Vol 13, Iss 4, p e1006326 (2017)
The type I interferon pathway plays a critical role in both host defense and tolerance against viral infection and thus requires refined regulatory mechanisms. RIPK3-mediated necroptosis has been shown to be involved in anti-viral immunity. However,
Externí odkaz:
https://doaj.org/article/1a2b52c24946483db0ac9fac820a7833
Autor:
Catherine Lemière, Caroline Tremblay, Mark FitzGerald, Shawn D Aaron, Richard Leigh, Louis-Philippe Boulet, James G Martin, Parameswaran Nair, Ronald Olivenstein, Simone Chaboillez
Publikováno v:
Canadian Respiratory Journal, Vol 18, Iss 5, Pp 278-282 (2011)
BACKGROUND: Noneosinophilic asthma has been regarded as a distinct phenotype characterized by a poor response to inhaled corticosteroids (ICS).
Externí odkaz:
https://doaj.org/article/177055beea7d4a2394f3b362b0a5b30e
Autor:
James G Martin, Kevin Schwartzman
Publikováno v:
Canadian Respiratory Journal, Vol 22, Iss 1, Pp e4-e7 (2015)
Externí odkaz:
https://doaj.org/article/6b600aa136684d398675deec165ec90c
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136284 (2015)
Endobronchial ultrasonography (EBUS) revealed differences in the thickness of the layer representing subepithelial tissues (L2) between human asthmatics and controls, but whether this measurement correlates with airway smooth muscle (ASM) remodeling
Externí odkaz:
https://doaj.org/article/381dcc7b94864361bdb9e3b0702de516
Autor:
John Mac Sharry, Karim H Shalaby, Cinzia Marchica, Soroor Farahnak, Tien Chieh-Li, Susan Lapthorne, Salman T Qureshi, Fergus Shanahan, James G Martin
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e98648 (2014)
Varying concentrations of lipopolysaccharide (LPS) in ovalbumin (OVA) may influence the airway response to allergic sensitization and challenge. We assessed the contribution of LPS to allergic airway inflammatory responses following challenge with LP
Externí odkaz:
https://doaj.org/article/71be7e6fe915453ea355f93cf2145ce5
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95566 (2014)
The airway epithelium may release pro-inflammatory cytokines and chemokines in the asthmatic airway. Sphingosine 1-phosphate (S1P) is a bioactive lipid, increased in the airways of asthmatics, that may trigger the release of the potent neutrophil che
Externí odkaz:
https://doaj.org/article/fb96b87126e647a592028da6d630bb1a
Autor:
Camille Audousset, Sana Swaleh, Ron Olivenstein, Motahareh Vameghestahbanati, Miranda Kirby, Alexandre Semionov, Benjamin M. Smith, James G. Martin
Publikováno v:
Respiratory Research, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract Background Mucus plugs have been described in the airways of asthmatic subjects, particularly those with associated with type 2 inflammation and sputum eosinophilia. In the current study we addressed the question of whether smoking, neutroph
Externí odkaz:
https://doaj.org/article/c998fb2a35a44688a5fec099975cfb46
Site of allergic airway narrowing and the influence of exogenous surfactant in the Brown Norway rat.
Autor:
Sana Siddiqui, Kimitake Tsuchiya, Paul-André Risse, Sharon R Bullimore, Andrea Benedetti, James G Martin
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29381 (2012)
The parameters R(N) (newtonian resistance), G (tissue damping), and H (tissue elastance) of the constant phase model of respiratory mechanics provide information concerning the site of altered mechanical properties of the lung. The aims of this study
Externí odkaz:
https://doaj.org/article/c982ee6ef2584329b47dcd6f931452c4
Autor:
Arina Morozan, Sydney Joy, Utako Fujii, Richard Fraser, Kevin Watters, James G. Martin, Inés Colmegna
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Systemic sclerosis (SSc) is an autoimmune disease characterized by vasculopathy, immune dysregulation, and multi-organ fibrosis. Interstitial lung disease (ILD) is a complication of SSc and a leading cause of SSc-death. The administration of
Externí odkaz:
https://doaj.org/article/9e5adbaa4c264153bf2be908b95707a0
Autor:
Sophie Mainguy-Seers, Francis Beaudry, Christopher Fernandez-Prada, James G. Martin, Jean-Pierre Lavoie
Publikováno v:
Cells; Volume 11; Issue 21; Pages: 3347
Extracellular vesicles (EVs) contribute to intercellular communication through the transfer of their rich cargo to recipient cells. The EVs produced by LPS-stimulated neutrophils from healthy humans and horses increase airway smooth muscle (ASM) prol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221f366b5ae27632c12c12886a053c12
https://pubmed.ncbi.nlm.nih.gov/36359743
https://pubmed.ncbi.nlm.nih.gov/36359743