Zobrazeno 1 - 10
of 846
pro vyhledávání: '"James G Fox"'
Autor:
Kenneth J Conley, Tracie A Seimon, Ioana S Popescu, James F X Wellehan, James G Fox, Zeli Shen, Jane Haakonsson, Anton Seimon, Ania Tomaszewicz Brown, Veronica King, Fred Burton, Paul P Calle
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0247010 (2021)
The Blue Iguana Recovery Programme maintains a captive breeding and head-starting program for endangered Grand Cayman blue iguanas (Cyclura lewisi) on Grand Cayman, Cayman Islands. In May 2015, program staff encountered two lethargic wild Grand Cayma
Externí odkaz:
https://doaj.org/article/08015c26f3e3478cb0fdba5982b665c2
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224950 (2019)
The common marmoset (Callithrix jacchus) is increasingly used as an animal model for biomedical research; however, gastrointestinal diseases causing significant morbidity are endemic in many captive marmoset colonies. Establishing gut microbiome patt
Externí odkaz:
https://doaj.org/article/ffdbc9235f734bee9e61147dafc8dfc6
Autor:
Vasudevan Bakthavatchalu, Katherine J Wert, Yan Feng, Anthony Mannion, Zhongming Ge, Alexis Garcia, Kathleen E Scott, Tyler J Caron, Carolyn M Madden, Johanne T Jacobsen, Gabriel Victora, Rudolf Jaenisch, James G Fox
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0194443 (2018)
Immune-compromised mouse models allow for testing the preclinical efficacy of human cell transplantations and gene therapy strategies before moving forward to clinical trials. However, CRISPR/Cas9 gene editing of the Wsh/Wsh mouse strain to create an
Externí odkaz:
https://doaj.org/article/b69d9562975649f5956ce47966a81b10
Autor:
Naresh S Redhu, Vasudevan Bakthavatchalu, Evan A Conaway, Dror S Shouval, Amy Tsou, Jeremy A Goettel, Amlan Biswas, Chuanwu Wang, Michael Field, Werner Muller, Andre Bleich, Ning Li, Georg K Gerber, Lynn Bry, James G Fox, Scott B Snapper, Bruce H Horwitz
Publikováno v:
eLife, Vol 6 (2017)
Infants with defects in the interleukin 10 receptor (IL10R) develop very early onset inflammatory bowel disease. Whether IL10R regulates lamina propria macrophage function during infant development in mice and whether macrophage-intrinsic IL10R signa
Externí odkaz:
https://doaj.org/article/724f8523dc5d4a638ab2b5308f22edd9
Autor:
Stephanie E Woods, Mia T Lieberman, Francois Lebreton, Elise Trowel, César de la Fuente-Núñez, Joanne Dzink-Fox, Michael S Gilmore, James G Fox
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169293 (2017)
Nonhuman primates are commonly used for cognitive neuroscience research and often surgically implanted with cephalic recording chambers for electrophysiological recording. Aerobic bacterial cultures from 25 macaques identified 72 bacterial isolates,
Externí odkaz:
https://doaj.org/article/02cb0a64142642ffb269f2c2437ada80
Autor:
Monika Burns, Aldo Amaya, Caroline Bodi, Zhongming Ge, Vasudevan Bakthavatchalu, Kathleen Ennis, Timothy C Wang, Michael Georgieff, James G Fox
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0173108 (2017)
Helicobacter pylori (H.pylori), a bacterial pathogen, is a causative agent of gastritis and peptic ulcer disease and is a strong risk factor for development of gastric cancer. Environmental conditions, such as poor dietary iron resulting in iron defi
Externí odkaz:
https://doaj.org/article/8503334b24b64e2fbdceb8a9d6edb14f
Autor:
Cassandra L Miller, Sureshkumar Muthupalani, Zeli Shen, Frauke Drees, Zhongming Ge, Yan Feng, Xiaowei Chen, Guanyu Gong, Karan K Nagar, Timothy C Wang, Frank B Gertler, James G Fox
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152940 (2016)
During a survey of clinical rectal prolapse (RP) cases in the mouse population at MIT animal research facilities, a high incidence of RP in the lamellipodin knock-out strain, C57BL/6-Raph1tm1Fbg (Lpd-/-) was documented. Upon further investigation, th
Externí odkaz:
https://doaj.org/article/ad22e9c5cf4e4321895699365f2a53f2
Autor:
Monika Burns, Sureshkumar Muthupalani, Zhongming Ge, Timothy C Wang, Vasudevan Bakthavatchalu, Catriona Cunningham, Kathleen Ennis, Michael Georgieff, James G Fox
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142630 (2015)
Iron deficiency anemia (IDA) affects > 500 million people worldwide, and is linked to impaired cognitive development and function in children. Helicobacter pylori, a class 1 carcinogen, infects about half of the world's population, thus creating a hi
Externí odkaz:
https://doaj.org/article/d61f32b16d5a413d933d1d3d432f7ede
Autor:
Alison Darby, Kvin Lertpiriyapong, Ujjal Sarkar, Uthpala Seneviratne, Danny S Park, Eric R Gamazon, Chara Batchelder, Cheryl Cheung, Ellen M Buckley, Nancy S Taylor, Zeli Shen, Steven R Tannenbaum, John S Wishnok, James G Fox
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100542 (2014)
Klebsiella oxytoca is an opportunistic pathogen implicated in various clinical diseases in animals and humans. Studies suggest that in humans K. oxytoca exerts its pathogenicity in part through a cytotoxin. However, cytotoxin production in animal iso
Externí odkaz:
https://doaj.org/article/16757046651b4fd8b2a8206fc6daf4ac
Autor:
Alton G Swennes, Alexander Sheh, Nicola M A Parry, Sureshkumar Muthupalani, Kvin Lertpiriyapong, Alexis García, James G Fox
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e106764 (2014)
Farnesoid X receptor (FXR) is a nuclear receptor that regulates bile acid metabolism and transport. Mice lacking expression of FXR (FXR KO) have a high incidence of foci of cellular alterations (FCA) and liver tumors. Here, we report that Helicobacte
Externí odkaz:
https://doaj.org/article/41d5037a4d6b4b26982af47d92c43c0b