Zobrazeno 1 - 10
of 45
pro vyhledávání: '"James G D Prendergast"'
Autor:
David Wragg, Elizabeth A J Cook, Perle Latré de Laté, Tatjana Sitt, Johanneke D Hemmink, Maurine C Chepkwony, Regina Njeru, E Jane Poole, Jessica Powell, Edith A Paxton, Rebecca Callaby, Andrea Talenti, Antoinette A Miyunga, Gideon Ndambuki, Stephen Mwaura, Harriet Auty, Oswald Matika, Musa Hassan, Karen Marshall, Timothy Connelley, Liam J Morrison, B Mark deC Bronsvoort, W Ivan Morrison, Philip G Toye, James G D Prendergast
Publikováno v:
PLoS Genetics, Vol 18, Iss 4, p e1010099 (2022)
East Coast fever, a tick-borne cattle disease caused by the Theileria parva parasite, is among the biggest natural killers of cattle in East Africa, leading to over 1 million deaths annually. Here we report on the genetic analysis of a cohort of Bos
Externí odkaz:
https://doaj.org/article/b0a1ab77394044a9b14c19369b4212a7
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006673 (2017)
Large-scale gene expression datasets are providing an increasing understanding of the location of cis-eQTLs in the human genome and their role in disease. However, little is currently known regarding the extent of regulatory site-sharing between gene
Externí odkaz:
https://doaj.org/article/4ef80935707e4eddaed761b6eae36318
Autor:
Abdulfatai Tijjani, Sumaya Kambal, Endashaw Terefe, Regina Njeru, Moses Ogugo, Gideon Ndambuki, Ayao Missohou, Amadou Traore, Bashir Salim, Chukwunonso Ezeasor, Claire D’andre H., Emmanuel T. Obishakin, Boubacar Diallo, Essodina Talaki, Issaka Y. Abdoukarim, Oyekanmi Nash, Richard Osei-Amponsah, Simeone Ravaorimanana, Youssouf Issa, Tsadkan Zegeye, Christopher Mukasa, Christian Tiambo, James G. D. Prendergast, Stephen J. Kemp, Jianlin Han, Karen Marshall, Olivier Hanotte
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-10 (2024)
Abstract The diversity in genome resources is fundamental to designing genomic strategies for local breed improvement and utilisation. These resources also support gene discovery and enhance our understanding of the mechanisms of resilience with appl
Externí odkaz:
https://doaj.org/article/ad4d2709fcf1417b813ff8b826e8cf07
Autor:
Andrea Talenti, Toby Wilkinson, Elizabeth A. Cook, Johanneke D. Hemmink, Edith Paxton, Matthew Mutinda, Stephen D. Ngulu, Siddharth Jayaraman, Richard P. Bishop, Isaiah Obara, Thibaut Hourlier, Carlos Garcia Giron, Fergal J. Martin, Michel Labuschagne, Patrick Atimnedi, Anne Nanteza, Julius D. Keyyu, Furaha Mramba, Alexandre Caron, Daniel Cornelis, Philippe Chardonnet, Robert Fyumagwa, Tiziana Lembo, Harriet K. Auty, Johan Michaux, Nathalie Smitz, Philip Toye, Christelle Robert, James G. D. Prendergast, Liam J. Morrison
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-14 (2024)
Abstract The African buffalo (Syncerus caffer) is a wild bovid with a historical distribution across much of sub-Saharan Africa. Genomic analysis can provide insights into the evolutionary history of the species, and the key selective pressures shapi
Externí odkaz:
https://doaj.org/article/3b169d2ff6e14178bc1d2d9d12a8737c
Autor:
James G D Prendergast, Colin A Semple
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003528 (2013)
Externí odkaz:
https://doaj.org/article/d7915eb074a748c38d7c1ad488730427
Autor:
Ian P M Tomlinson, Luis G Carvajal-Carmona, Sara E Dobbins, Albert Tenesa, Angela M Jones, Kimberley Howarth, Claire Palles, Peter Broderick, Emma E M Jaeger, Susan Farrington, Annabelle Lewis, James G D Prendergast, Alan M Pittman, Evropi Theodoratou, Bianca Olver, Marion Walker, Steven Penegar, Ella Barclay, Nicola Whiffin, Lynn Martin, Stephane Ballereau, Amy Lloyd, Maggie Gorman, Steven Lubbe, COGENT Consortium, CORGI Collaborators, EPICOLON Consortium, Bryan Howie, Jonathan Marchini, Clara Ruiz-Ponte, Ceres Fernandez-Rozadilla, Antoni Castells, Angel Carracedo, Sergi Castellvi-Bel, David Duggan, David Conti, Jean-Baptiste Cazier, Harry Campbell, Oliver Sieber, Lara Lipton, Peter Gibbs, Nicholas G Martin, Grant W Montgomery, Joanne Young, Paul N Baird, Steven Gallinger, Polly Newcomb, John Hopper, Mark A Jenkins, Lauri A Aaltonen, David J Kerr, Jeremy Cheadle, Paul Pharoah, Graham Casey, Richard S Houlston, Malcolm G Dunlop
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002105 (2011)
Genome-wide association studies (GWAS) have identified 14 tagging single nucleotide polymorphisms (tagSNPs) that are associated with the risk of colorectal cancer (CRC), and several of these tagSNPs are near bone morphogenetic protein (BMP) pathway l
Externí odkaz:
https://doaj.org/article/c10c8a90b2ce4383b4aa02c682b34728
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17570 (2011)
Second generation sequencing has prompted a number of groups to re-interrogate the transcriptomes of several bacterial and archaeal species. One of the central findings has been the identification of complex networks of small non-coding RNAs that pla
Externí odkaz:
https://doaj.org/article/64c6d4e567d546649a2259f40c85c98b
Autor:
Jessica Powell, Andrea Talenti, Andressa Fisch, Johanneke D. Hemmink, Edith Paxton, Philip Toye, Isabel Santos, Beatriz R. Ferreira, Tim K. Connelley, Liam J. Morrison, James G. D. Prendergast
Publikováno v:
Powell, J, Talenti, A, Fisch, A, Hemmink, H, Paxton, E, Toye, P, Santos, I, Ferreira, B R, Connelley, T, Morrison, L & Prendergast, J 2023, ' Profiling the immune epigenome across global cattle breeds ', Genome Biology, vol. 24, 127, pp. 1-31 . https://doi.org/10.1186/s13059-023-02964-3
Background Understanding the variation between well and poorly adapted cattle breeds to local environments and pathogens is essential for breeding cattle with improved climate and disease-resistant phenotypes. Although considerable progress has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84556e3767a69e64abfeaa610d17118
https://hdl.handle.net/20.500.11820/45ec7088-ef67-4fb6-b4d3-79bddd4dc371
https://hdl.handle.net/20.500.11820/45ec7088-ef67-4fb6-b4d3-79bddd4dc371
Autor:
Manu Kumar Gundappa, Diego Robledo, Alastair Hamilton, Ross D. Houston, James G. D. Prendergast, Daniel J. Macqueen
Whole genome sequencing (WGS), despite its advantages, is yet to replace alternative methods for genotyping single nucleotide variants (SNVs). Structural variants (SVs) have larger effects on traits than SNVs, but are more challenging to accurately g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::095ac5d7c91b9e38a0c1eb828e2b4188
https://doi.org/10.1101/2023.03.05.531147
https://doi.org/10.1101/2023.03.05.531147
Autor:
Valentina Riggio, Abdulfatai Tijjani, Rebecca Callaby, Andrea Talenti, David Wragg, Emmanuel T. Obishakin, Chukwunonso Ezeasor, Frans Jongejan, Ndudim I. Ogo, Fred Aboagye-Antwi, Alassane Toure, Jahashi Nzalawahej, Boubacar Diallo, Ayao Missohou, Adrien M. G. Belem, Appolinaire Djikeng, Nick Juleff, Josephus Fourie, Michel Labuschagne, Maxime Madder, Karen Marshall, James G. D. Prendergast, Liam J. Morrison
Publikováno v:
Riggio, V, Tijjani, A, Callaby, R, Talenti, A, Wragg, D, Obishakin, E T, Ezeasor, C, Jongejan, F, Ogo, N I, Aboagye-Antwi, F, Toure, A, Nzalawahe, J, Diallo, B, Missohou, A, Belem, A M G, Djikeng, A, Juleff, N, Fourie, J, Labuschagne, M, Madder, M, Marshall, K, Prendergast, J & Morrison, L 2022, ' Assessment of genotyping array performance for genome-wide association studies and imputation in African cattle ', Genetics Selection Evolution, vol. 54, no. 1, 54:58, pp. 1-23 . https://doi.org/10.1186/s12711-022-00751-5
Background In cattle, genome-wide association studies (GWAS) have largely focused on European or Asian breeds, using genotyping arrays that were primarily designed for European cattle. Because there is growing interest in performing GWAS in African b