Zobrazeno 1 - 10
of 11
pro vyhledávání: '"James Froberg"'
Autor:
Yanxiong Pan, Brett R Goldsmith, Sung Oh Woo, James Froberg, Yongki Choi, Sakurako Tani, Zhongyu Yang
Publikováno v:
ACS Appl Electron Mater
Although graphene-based biosensors provid extreme sensitivity for the detection of atoms, gases, and biomolecules, the specificity of graphene biosensors to the target molecules requires surface decoration of graphene with bifunctional linkers such p
Autor:
Jenna Osborn, Amanda E. Brooks, James Froberg, Yongki Choi, Sanku Mallik, Todd Molden, Jessica E Pullan, Jacob Shreffler, Kausik Sarkar, Kara N. Gange
Publikováno v:
Nanoscale Adv
Exosomes are naturally secreted extracellular bilayer vesicles (diameter 40–130 nm), which have recently been found to play a critical role in cell-to-cell communication and biomolecule delivery. Their unique characteristics—stability, permeabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c49302d25fecbb58b8b1156e61857e4a
https://europepmc.org/articles/PMC9410358/
https://europepmc.org/articles/PMC9410358/
Autor:
Matthew Confeld, Michael A. Hollingsworth, Sanku Mallik, James Froberg, Li Feng, Heather Jensen-Smith, Babak Mamnoon, Mohiuddin A. Quadir, Yongki Choi, Jiha Kim, Priyanka Ray
Publikováno v:
Mol Pharm
In pancreatic ductal adenocarcinoma (PDAC), early onset of hypoxia triggers remodeling of the extracellular matrix, epithelial-to-mesenchymal transition, increased cell survival, the formation of cancer stem cells, and drug resistance. Hypoxia in PDA
Autor:
Jasmin Farmakes, James Froberg, Tayebeh Anajafi, Sanku Mallik, D. K. Srivastava, Abbas Sedigh, Woo-Sik Choi, Zhongyu Yang, Yongki Choi
Publikováno v:
Chemical Communications. 54:10248-10251
The dynamic interactions of an individual matrix metalloproteinase-1 were imaged and monitored in the presence of either triple-helical or non-triple-helical, partially-structured collagen-mimic substrates. The enzyme exhibited ten-fold increased cat
Autor:
Zhongyu Yang, Steven Y. Qian, Jiajia Rao, James Froberg, Jasmin Farmakes, Michael D. Bridges, Sunanda Neupane, Guodong Liu, Yanxiong Pan, Yongki Choi
Publikováno v:
Nanoscale. 9:3512-3523
Silica nanoparticles (SiNPs) are important nano-sized, solid-state carriers/hosts to load, store, and deliver biological or pharmaceutical cargoes. They are also good potential solid supports to immobilize proteins for fundamental protein structure a
Autor:
Manas K. Haldar, D. K. Srivastava, Sanku Mallik, Junru Yu, Abbas Sedigh, Yongki Choi, Seungyong You, James Froberg
Publikováno v:
Chemical Communications. 53:3307-3310
Using single-molecule approaches, we directly observed the dynamic interaction between HDAC8 and various ligands as well as conformational interconversions during the catalytic reaction. Statistical analysis identified key kinetic parameters, demonst
Autor:
Pawel P. Borowicz, John C. Wilkinson, Sanku Mallik, Yongki Choi, James Froberg, Fataneh Karandish
Often cancer relapses after an initial response to chemotherapy because of the tumor’s heterogeneity and the presence of progenitor stem cells, which can renew. To overcome drug resistance, metastasis, and relapse in cancer, a promising approach is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b738abe283329cdb94b7ba5e482eae3
https://europepmc.org/articles/PMC5818288/
https://europepmc.org/articles/PMC5818288/
Autor:
Yongki Choi, James Froberg, Kausik Sarkar, Kara N. Gange, Sanku Mallik, Lang Xia, Krishna N. Kumar, Prajakta Kulkarni, Fataneh Karandish
Publikováno v:
Ultrasound in medicinebiology. 44(2)
Polymersomes are a class of artificial vesicles prepared from amphiphilic polymers. Like lipid vesicles (liposomes), they too can encapsulate hydrophilic and hydrophobic drug molecules in the aqueous core and the hydrophobic bilayer respectively, but
Publikováno v:
The Journal of the Acoustical Society of America. 145:1894-1894
Exosomes are naturally secreted bilayer vesicles ranging in size from 40 to 200 nm that play a critical role in cell-to-cell communications and protein and RNA delivery. Researchers have explored exosomes as potential drug delivery vehicles due to th
Publikováno v:
Applied Physics Letters. 110:203701
Nanoelectronic devices integrated with dielectrophoresis (DEP) have been promoted as promising platforms for trapping, separating, and concentrating target biomarkers and cancer cells from a complex medium. Here, we visualized DEP and DEP gradients i