Zobrazeno 1 - 10
of 11
pro vyhledávání: '"James Frederiksen"'
Autor:
Christopher R. Reed, Desiree Bonadonna, James C. Otto, Charles Griffin McDaniel, Charlene Vongai Chabata, Maragatha Kuchibhatla, James Frederiksen, Juliana M. Layzer, Gowthami M. Arepally, Bruce A. Sullenger, Elisabeth T. Tracy
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 27, Iss , Pp 524-534 (2022)
Extracorporeal membrane oxygenation (ECMO) requires anticoagulation to prevent clotting when the patient’s blood contacts the circuit. Unfractionated heparin (UFH) usually prevents clotting but can cause life-threatening bleeding. An anticoagulant
Externí odkaz:
https://doaj.org/article/d7436a28615d421ab29cdaa12ab5b3e2
Publikováno v:
RNA. 29:455-462
In this short Perspective, we discuss the history of, and recent progress toward, the development of aptamers that can serve as rapid onset anticoagulants during cardiopulmonary bypass (CPB), extracorporeal membrane oxygenation (ECMO), and catheter-b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ce60ae9b186fa95bc94d0a8efd52b60
https://doi.org/10.1261/rna.079503.122
https://doi.org/10.1261/rna.079503.122
Autor:
Mohamad-Gabriel Alameh, Marice Alcantara, Jessica Alluin, Paola Amero, Virginia Arechavala-Gomeza, George A. Calin, David R. Corey, Hagen Cramer, Niels Dammes, Daniel W. Drolet, James Frederiksen, Amy D. Gelinas, Nagy A. Habib, Inbal Hazan-Halevy, Kevin Holm, Nebojsa Janjic, Krystal C. Johnson, Samantha T. Johnson, Edo Kon, Marcin Kortylewski, Dalit Landesman-Milo, Marc M. Lemaitre, Christopher Lincoln, Gabriel Lopez-Berestein, Sean A. Lynch, Selin Oncul, Rachel M. Ostroff, Dan Peer, Cristian Rodriguez-Aguayo, John C. Rohloff, Daniel Rossi, John J. Rossi, Thomas M. Rupp, Daniel J. Schneider, Patricia Soblechero-Martín, Min-Sun Song, Anil K. Sood, Yu-Lin Su, Bruce A. Sullenger, Jon Voutila, Drew Weissman, Preston Williams, Chunsong Yu, Haixiang Yu, Zhuoran Zhang, Jiehua Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::716f968d155a5029d4ea30ec9d4c3e57
https://doi.org/10.1016/b978-0-12-821595-1.09994-2
https://doi.org/10.1016/b978-0-12-821595-1.09994-2
Autor:
Bruce A. Sullenger, J.L. Lohrmann, K. Perry, Steven Stayrook, Ruwan Gunaratne, Sriram Krishnaswamy, Gowthami M. Arepally, Shekhar Kumar, Nabil K. Thalji, Rodney M. Camire, James Frederiksen, Kristin M. Bompiani, C.V. Chabata
Publikováno v:
Nature Biotechnology. 36:606-613
Unfractionated heparin (UFH), the standard anticoagulant for cardiopulmonary bypass (CPB) surgery, carries a risk of post-operative bleeding and is potentially harmful in patients with heparin-induced thrombocytopenia-associated antibodies. To improv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be80bd64ad15b819e25ae39cc77f43e7
https://doi.org/10.1038/nbt.4153
https://doi.org/10.1038/nbt.4153
Publikováno v:
Current opinion in hematology. 25(5)
Since the selection of the first thrombin-binding aptamer in 1992, the use of nucleic acid aptamers to target specific coagulation factors has emerged as a valuable approach for generating novel anticoagulant and procoagulant therapeutics. Herein, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ce03fe7f7e1ce53609a9f7a1add1039
https://pubmed.ncbi.nlm.nih.gov/30015643
https://pubmed.ncbi.nlm.nih.gov/30015643
Increased yield of endothelial cells from peripheral blood for cell therapies and tissue engineering
Autor:
Fu-Hsiung Lin, Oscar Alzate, AnnMarie K Rodriguez, Ryan M. Jamiolkowski, James Frederiksen, George A. Truskey, Sa Do Kang, Siyao Liu, Lukas G. Keil, Alexandra E. Jantzen, Thomas Stabler, Hardean E. Achneck, Marcus D. Darrabie, Jose G. Mantilla, N. Rebecca Haley, Lauren J. Galinat, Justin M. Haseltine, Tim A. Carlon, Jason D. Allen, Maria Noviani, Antonio J. Arciniegas
Aim: Peripheral blood-derived endothelial cells (pBD-ECs) are an attractive tool for cell therapies and tissue engineering, but have been limited by their low isolation yield. We increase pBD-EC yield via administration of the chemokine receptor type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b844d068917110b139efbc579bab635
https://europepmc.org/articles/PMC4489558/
https://europepmc.org/articles/PMC4489558/
Autor:
Miki Yamada, Amir Sheikh, Kevin Collins, James Frederiksen, George Quick, Andrew Lodge, Mihai Podgoreanu
Publikováno v:
Circulation. 130
Previous studies suggest that immature hearts are more tolerant to ischemia than adult myocardium; whether differences exist during ontogenic development in severity of global myocardial ischemia/reperfusion (I/R) injury associated with cardiac surge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a20f827d0219128a4edf75ea96d613e1
https://doi.org/10.1161/circ.130.suppl_2.11685
https://doi.org/10.1161/circ.130.suppl_2.11685
Autor:
Bruce A. Sullenger, George A. Pitoc, Kristin M. Bompiani, James Frederiksen, George B. Mackensen, Jens L. Lohrmann
SummaryCoordinated enzymatic reactions regulate blood clot generation. To explore the contributions of various coagulation enzymes in this process, we utilized a panel of aptamers against factors VIIa, IXa, Xa, and prothrombin. Each aptamer dose-depe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6836cffa66f3dea7b4254867339df2e2
https://europepmc.org/articles/PMC4134678/
https://europepmc.org/articles/PMC4134678/
Autor:
Rodney M. Camire, Michelle D. Ho, Nabil K. Thalji, Gowthami M. Arepally, Ruwan Gunaratne, James Frederiksen, Bruce A. Sullenger
Publikováno v:
Blood. 128:3823-3823
Despite notable disadvantages, unfractionated heparin (UFH) remains the standard anticoagulant for clinical procedures requiring potent and reversible anticoagulation such as cardiopulmonary bypass (CPB). Limitations of UFH that contribute to patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::141578dfc22b109e4374aa3c5a3404b8
https://doi.org/10.1182/blood.v128.22.3823.3823
https://doi.org/10.1182/blood.v128.22.3823.3823
Autor:
Thomas C. Sebo, James Frederiksen, Nalini M. Rajamannan, Thomas C. Spelsberg, Stuart R. Stock, Thenappan Thenappan, Khuram H Siddiqi, Thomas B. Nealis, Stephen W. Carmichael, Robert O. Bonow, Malayannan Subramanium, William D. Edwards
Publikováno v:
Journal of the American College of Cardiology. 43:A433
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec97f1c8a987d6a64a30c059b09f47bf
https://doi.org/10.1016/s0735-1097(04)91824-4
https://doi.org/10.1016/s0735-1097(04)91824-4