Zobrazeno 1 - 10
of 28
pro vyhledávání: '"James Fodor"'
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-11 (2020)
Abstract Background Network motifs are connectivity structures that occur with significantly higher frequency than chance, and are thought to play important roles in complex biological networks, for example in gene regulation, interactomes, and metab
Externí odkaz:
https://doaj.org/article/bbd6a5aea6f445c2bbf9d9cca63e0b8c
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Abstract Abacavir is an antiretroviral drug used to reduce human immunodeficiency virus (HIV) replication and decrease the risk of developing acquired immune deficiency syndrome (AIDS). However, its therapeutic value is diminished by the fact that it
Externí odkaz:
https://doaj.org/article/6786753185214d0691d8d5644bacc65a
Autor:
Christopher Szeto, Joseph I. Bloom, Hannah Sloane, Christian A. Lobos, James Fodor, Dhilshan Jayasinghe, Demetra S. M. Chatzileontiadou, Emma J. Grant, Ashley M. Buckle, Stephanie Gras
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7081 (2020)
The interaction between T cell receptor (TCR) and peptide (p)-Human Leukocyte Antigen (HLA) complexes is the critical first step in determining T cell responses. X-ray crystallographic studies of pHLA in TCR-bound and free states provide a structural
Externí odkaz:
https://doaj.org/article/31cf5e6e498248b690293c52af96d339
Autor:
Sarah N Le, Benjamin T Porebski, Julia McCoey, James Fodor, Blake Riley, Marlena Godlewska, Monika Góra, Barbara Czarnocka, J Paul Banga, David E Hoke, Itamar Kass, Ashley M Buckle
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0142615 (2015)
Thyroid peroxidase (TPO) catalyses the biosynthesis of thyroid hormones and is a major autoantigen in Hashimoto's disease--the most common organ-specific autoimmune disease. Epitope mapping studies have shown that the autoimmune response to TPO is di
Externí odkaz:
https://doaj.org/article/4b2bc99a9c1a4ce2b00e1f925ee7cc79
Autor:
James Fodor, Blake T. Riley, Kirill Tsyganov, Anne Geert Volbeda, Daniel C. Nelson, Kylie A Farrow, Brooke K. Hayes, Colin J. Jackson, Sheena McGowan, Sebastian S. Broendum, Ben E. Clifton, Ryan D. Heselpoth, Jeroen D. C. Codée, Felix Kraus, Daniel E. Williams, Nyssa Drinkwater, Ashley M. Buckle
Publikováno v:
Molecular Microbiology, 116(2), 397-415. WILEY
Endolysin enzymes from bacteriophage cause bacterial lysis by degrading the peptidoglycan cell wall. The streptococcal C1 phage endolysin PlyC, is the most potent endolysin described to date and can rapidly lyse group A, C, and E streptococci. PlyC i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846e2ef7204d60bb22eabac1ed34cebe
https://doi.org/10.1111/mmi.14719
https://doi.org/10.1111/mmi.14719
Publikováno v:
The Journal of Immunology. 200:4134-4145
A structural characterization of the interaction between αβ TCRs and cognate peptide–MHC (pMHC) is central to understanding adaptive T cell–mediated immunity. X-ray crystallography, although the source of much structural data, traditionally pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aefd9b856f4da1f5fd2f91809db3222
https://doi.org/10.4049/jimmunol.1800315
https://doi.org/10.4049/jimmunol.1800315
Autor:
James Fodor
He has written or edited more than 30 books, his arguments for God and Jesus are frequently cited by Christian apologists around the world, and he has severely overstated his case through a series of blatant mischaracterizations and philosophical blu
Autor:
James Fodor, Itamar Kass, Blake T. Riley, Sheena McGowan, Mauricio G. S. Costa, Emilia M. Marijanovic, Ashley M. Buckle, David E. Hoke, Benjamin T. Porebski
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-15 (2019)
Scientific Reports
Scientific Reports
Serine proteinase inhibitors (serpins), typically fold to a metastable native state and undergo a major conformational change in order to inhibit target proteases. However, conformational lability of the native serpin fold renders them susceptible to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c98624ecf8d4a6635d3d8605108098
Autor:
James Fodor
Publikováno v:
Wilderness Wanderings ISBN: 9780429503054
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a418a298e635f2642bd4e8d4e8e2e0d
https://doi.org/10.4324/9780429503054-14
https://doi.org/10.4324/9780429503054-14