Zobrazeno 1 - 10
of 105
pro vyhledávání: '"James F. Wolfe"'
Publikováno v:
Bioorganic & Medicinal Chemistry. 12:5711-5717
A series of 2-substituted-3-arylpyrido[2,3- d ]pyrimidinones was prepared for evaluation as potential anticonvulsants. In murine screening, compounds 4a – c having a 2-oxo-2-(4-pyridyl)ethyl group in the 2-position and a 2-substituted phenyl moiety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18a7b2015d56a6c12ddbcf91a9c26c57
https://doi.org/10.1016/j.bmc.2004.07.068
https://doi.org/10.1016/j.bmc.2004.07.068
Publikováno v:
Organic Letters. 2:2643-2646
[reaction: see text]Phenylacetic acid dianions react via what appears to be an S(RN)1 process with aryl halides under photostimulation to afford aryl substitution products 5 and 6. When the counterion is K+, only 4-biphenylacetic acids 5 are obtained
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee1e9f0c69c815e826d0f0f8b6a5de6
https://doi.org/10.1021/ol006177f
https://doi.org/10.1021/ol006177f
Autor:
James M. Tanko, Joseph S. Merola, Stacey N. Greenwood, James F. Wolfe, Sushama A. Dandekar, Stéphane Mabic, Thomas D. Greenwood
Publikováno v:
The Journal of Organic Chemistry. 64:1543-1553
The tricyclic title compounds, 4 and 5, were synthesized by initial alkylation of the lithium monoenolates of N,N,N‘,N‘-tetramethylbutanediamide (6) and N,N,N‘,N‘-tetramethylpentanediamide (19) with 2-iodobenzyl chloride in liquid NH3 at −6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bd3d5b2be0bba7ecf93a4bc44ffbf18
https://doi.org/10.1021/jo982000b
https://doi.org/10.1021/jo982000b
Publikováno v:
Expert Opinion on Therapeutic Patents. 8:361-381
This article summarises reports of new compounds with anticonvulsant activity that have appeared in the patent literature over the past five years. The subject compounds are arranged and discussed according to the following two major categories: new
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c3817052ba9efa379db00879d53b47f
https://doi.org/10.1517/13543776.8.4.361
https://doi.org/10.1517/13543776.8.4.361
Autor:
Jyothi S. Pisipati, Jim-Wah Wong, Godson C. Nwokogu, Thomas D. Greenwood, Kenneth J. Natalie, Patrick T. Flaherty, James F. Wolfe
Publikováno v:
The Journal of Organic Chemistry. 62:6152-6159
Carbanions generated from 2,4,4-trimethyl-2-oxazoline (1a), 2-benzyl-4,4-dimethyl-2-oxazoline (1b), 2,4-dimethylthiazole (13a), 2-benzyl-4-methylthiazole (13b), N,N-dimethylacetamide (17a), tert-butyl acetate (17b), ethyl phenylacetate (17c), N-methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df0dbf5097b61fa8b7888ee8d1fd2f20
https://doi.org/10.1021/jo962353f
https://doi.org/10.1021/jo962353f
Publikováno v:
Journal of Heterocyclic Chemistry. 34:817-821
Recently we reported the synthesis in polyphosphoric acid of a graft copolymer consisting of a rigid-rod poly[benzo(1,2-d;4,5-d′)bisthiazole-2,6-diyl]-1,4-phenylene backbone and flexible poly(oxy-1,3-phenylenecarbonyl-1,4-phenylene) side-chains [1]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0402ed3a029ce853ed0f8b10d11961e
https://doi.org/10.1002/jhet.5570340318
https://doi.org/10.1002/jhet.5570340318
Publikováno v:
ChemInform. 23
To the Editor: In a recent paper we reported the synthesis and anticonvulsant properties of a series of new 2-substituted 3-aryl-4(3H)-quinazolinone analogues of 2 methyl-3-o-tolyl-4(3H)-quinazolinone (methaqualone). Preliminary screening of these co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5689692f3c727beaeea4f6de68b71aaa
https://doi.org/10.1002/chin.199221199
https://doi.org/10.1002/chin.199221199
Publikováno v:
ChemInform. 28
Recently we reported the synthesis in polyphosphoric acid of a graft copolymer consisting of a rigid-rod poly[benzo(1,2-d;4,5-d′)bisthiazole-2,6-diyl]-1,4-phenylene backbone and flexible poly(oxy-1,3-phenylenecarbonyl-1,4-phenylene) side-chains [1]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::92f9515319218baf23a963ee96852be5
https://doi.org/10.1002/chin.199743148
https://doi.org/10.1002/chin.199743148
Autor:
Joseph S. Merola, Stéphane Mabic, Sushama A. Dandekar, Stacey N. Greenwood, James F. Wolfe, James M. Tanko, Thomas D. Greenwood
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78ebebd21b299d7e8ae29f4a54dce8c2
https://doi.org/10.1002/chin.199930132
https://doi.org/10.1002/chin.199930132
Publikováno v:
Synthesis of Lactones and Lactams (1993)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f1dd071b36aa22437b61cb39e94a861
https://doi.org/10.1002/9780470771594.ch8
https://doi.org/10.1002/9780470771594.ch8
