Zobrazeno 1 - 10
of 24
pro vyhledávání: '"James F. Theis"'
Autor:
William D. Tolbert, Dung N. Nguyen, Marina Tuyishime, Andrew R. Crowley, Yaozong Chen, Shalini Jha, Derrick Goodman, Valerie Bekker, Sarah V. Mudrak, Anthony L. DeVico, George K. Lewis, James F. Theis, Abraham Pinter, M. Anthony Moody, David Easterhoff, Kevin Wiehe, Justin Pollara, Kevin O. Saunders, Georgia D. Tomaras, Margaret Ackerman, Guido Ferrari, Marzena Pazgier
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
Passive transfer of monoclonal antibodies (mAbs) of human origin into Non-Human Primates (NHPs), especially those which function predominantly by a Fc-effector mechanism, requires an a priori preparation step, in which the human mAb is reengineered t
Externí odkaz:
https://doaj.org/article/ebe45cad4e6d401b8cdeec5671af1e07
Publikováno v:
MedEdPORTAL, Vol 16 (2020)
Introduction As evidenced by student performance on various assessments, pharmacotherapy remains a comparative weakness in undergraduate medical education, with several institutions developing novel strategies for students to apply these principles i
Externí odkaz:
https://doaj.org/article/3d7c98895bd14ea39622bc50b57fceca
Autor:
Todd Bradley, Justin Pollara, Sampa Santra, Nathan Vandergrift, Srivamshi Pittala, Chris Bailey-Kellogg, Xiaoying Shen, Robert Parks, Derrick Goodman, Amanda Eaton, Harikrishnan Balachandran, Linh V. Mach, Kevin O. Saunders, Joshua A. Weiner, Richard Scearce, Laura L. Sutherland, Sanjay Phogat, Jim Tartaglia, Steven G. Reed, Shiu-Lok Hu, James F. Theis, Abraham Pinter, David C. Montefiori, Thomas B. Kepler, Kristina K. Peachman, Mangala Rao, Nelson L. Michael, Todd J. Suscovich, Galit Alter, Margaret E. Ackerman, M. Anthony Moody, Hua-Xin Liao, Georgia Tomaras, Guido Ferrari, Bette T. Korber, Barton F. Haynes
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
A previous human HIV-1 vaccine clinical trial, boosting with HIV envelope protein from two strains, demonstrated moderate vaccine efficacy. Here, Bradleyet al. show that a pentavalent HIV envelope protein boost improves protection from viral challeng
Externí odkaz:
https://doaj.org/article/c5007d852a844f28b824be4c091a1102
Publikováno v:
MedEdPORTAL : the Journal of Teaching and Learning Resources
MedEdPORTAL, Vol 16 (2020)
MedEdPORTAL, Vol 16 (2020)
Introduction As evidenced by student performance on various assessments, pharmacotherapy remains a comparative weakness in undergraduate medical education, with several institutions developing novel strategies for students to apply these principles i
Autor:
Linh Mach, Bette T. Korber, Robert Parks, Hua-Xin Liao, Steven G. Reed, Barton F. Haynes, Amanda Eaton, Georgia D. Tomaras, Richard M. Scearce, Nelson L. Michael, Xiaoying Shen, James F. Theis, Galit Alter, M. Anthony Moody, Kristina K. Peachman, Srivamshi Pittala, Shiu Lok Hu, Guido Ferrari, David C. Montefiori, Harikrishnan Balachandran, Mangala Rao, Sanjay Phogat, Derrick Goodman, Thomas B. Kepler, Laura L. Sutherland, Margaret E. Ackerman, Todd Bradley, Joshua A. Weiner, Kevin O. Saunders, Justin Pollara, Sampa Santra, Jim Tartaglia, Nathan Vandergrift, Abraham Pinter, Todd J. Suscovich, Chris Bailey-Kellogg
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications
The RV144 Thai trial HIV-1 vaccine of recombinant poxvirus (ALVAC) and recombinant HIV-1 gp120 subtype B/subtype E (B/E) proteins demonstrated 31% vaccine efficacy. Here we design an ALVAC/Pentavalent B/E/E/E/E vaccine to increase the diversity of gp
Publikováno v:
Molecular Genetics and Genomics
Long gaps between active replication origins probably occur frequently during chromosome replication, but little is known about how cells cope with them. To address this issue, we deleted replication origins from S. cerevisiae chromosome III to creat
Autor:
Fu-Jung Chang, Jeremy A. Miller, Carol S. Newlon, Michael Weinreich, James F. Theis, Conrad A. Nieduszynski
Publikováno v:
Molecular and Cellular Biology. 28:5071-5081
Saccharomyces cerevisiae chromosome III encodes 11 autonomously replicating sequence (ARS) elements that function as chromosomal replicators. The essential 11-bp ARS consensus sequence (ACS) that binds the origin recognition complex (ORC) has been ex
Autor:
George F. Babcock, James F. Theis, Carol S. Newlon, Yinhuai Chen, Yolanda Sanchez, Kaila L. Schollaert, Julie M. Caldwell
Publikováno v:
The Journal of Cell Biology
The S-phase checkpoint activated at replication forks coordinates DNA replication when forks stall because of DNA damage or low deoxyribonucleotide triphosphate pools. We explore the involvement of replication forks in coordinating the S-phase checkp
Autor:
Michael L. Tobin, Clelia Maciariello, Malgorzata Korus, Sahba Tabrizifard, Giordano Liberi, Carmela Irene, Ann Dershowitz, James F. Theis, Lucia Fabiani, Carol S. Newlon
Publikováno v:
Genetics. 177:1445-1458
Eukaryotic chromosomes are duplicated during S phase and transmitted to progeny during mitosis with high fidelity. Chromosome duplication is controlled at the level of replication initiation, which occurs at cis-acting replicator sequences that are s
Autor:
James F. Theis, Carol S. Newlon
Publikováno v:
BioEssays. 24:300-304
Replication origins, which are responsible for initiating the replication of eukaryotic chromosomal DNAs, are spaced at intervals of 40 to 200 kb. Although the sets of proteins that assemble at replication origins during G(1) to form pre-replicative