Zobrazeno 1 - 10
of 42
pro vyhledávání: '"James F. Striebel"'
Autor:
Brent Race, Chase Baune, Katie Williams, James F. Striebel, Andrew G. Hughson, Bruce Chesebro
Publikováno v:
Veterinary Research, Vol 53, Iss 1, Pp 1-9 (2022)
Abstract Chronic wasting disease (CWD) is a prion disease of cervids including deer, elk, reindeer, and moose. Human consumption of cervids is common, therefore assessing the risk potential of CWD transmission to humans is critical. In a previous stu
Externí odkaz:
https://doaj.org/article/b984f435e5da496dbfd4f1678c8d4255
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/ce719585b7a74ff686d0c8c1896b8de2
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-23 (2021)
Abstract Background Past experiments studying innate immunity in the central nervous system (CNS) utilized microglia obtained from neonatal mouse brain, which differ developmentally from adult microglia. These differences might impact our current und
Externí odkaz:
https://doaj.org/article/19ac55a4bdac4bbd9432abef4403dd48
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-26 (2021)
Abstract Accumulation of misfolded host proteins is central to neuropathogenesis of numerous human brain diseases including prion and prion-like diseases. Neurons of retina are also affected by these diseases. Previously, our group and others found t
Externí odkaz:
https://doaj.org/article/84a6bced1441416fb121b7d946b40211
Autor:
James F. Striebel, Brent Race, Katie Williams, James A. Carroll, Mikael Klingeborn, Bruce Chesebro
Publikováno v:
Acta Neuropathologica Communications, Vol 7, Iss 1, Pp 1-15 (2019)
Abstract Degeneration of photoreceptors in the retina is a major cause of blindness in humans. Often retinal degeneration is due to inheritance of mutations in genes important in photoreceptor (PR) function, but can also be induced by other events in
Externí odkaz:
https://doaj.org/article/8472d92cf55f480c92b000fea3cb1737
Publikováno v:
Neurobiology of Disease, Vol 144, Iss , Pp 105057- (2020)
Tau aggregates consisting of hyperphosphorylated tau fibrils are associated with many neurodegenerative diseases, including Alzheimer's disease, Pick's disease, frontotemporal dementia, and progressive supranuclear palsy. Tau may contribute to the pa
Externí odkaz:
https://doaj.org/article/1b036cefd78a4720bf28343e06bb03da
Autor:
Brent Race, Katie Williams, Chase Baune, James F. Striebel, Clayton W. Winkler, James A. Carroll, Sandra E. Encalada, Bruce Chesebro
Publikováno v:
Viruses, Vol 13, Iss 7, p 1391 (2021)
In prion diseases, the spread of infectious prions (PrPSc) is thought to occur within nerves and across synapses of the central nervous system (CNS). However, the mechanisms by which PrPSc moves within axons and across nerve synapses remain undetermi
Externí odkaz:
https://doaj.org/article/ee9947329e504735bca8307e5764e9d5
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-26 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Accumulation of misfolded host proteins is central to neuropathogenesis of numerous human brain diseases including prion and prion-like diseases. Neurons of retina are also affected by these diseases. Previously, our group and others found that prion
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-23 (2021)
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-23 (2021)
BackgroundPast experiments studying innate immunity in the central nervous system (CNS) utilized microglia obtained from neonatal mouse brain, which differ developmentally from adult microglia. These differences might impact our current understanding
Autor:
Brent Race, Katie Williams, Chase Baune, James F. Striebel, Dan Long, Tina Thomas, Lori Lubke, Bruce Chesebro, James A. Carroll
Publikováno v:
PLOS ONE. 17:e0276850
Microglia (MG) are critical to host defense during prion infection, but the mechanism(s) of this neuroprotection are poorly understood. To better examine the influence of MG during prion infection, we reduced MG in the brains of C57BL/10 mice using P