Zobrazeno 1 - 10
of 141
pro vyhledávání: '"James F. Markworth"'
Autor:
Jesus A Castor-Macias, Jacqueline A Larouche, Emily C Wallace, Bonnie D Spence, Alec Eames, Pamela Duran, Benjamin A Yang, Paula M Fraczek, Carol A Davis, Susan V Brooks, Krishna Rao Maddipati, James F Markworth, Carlos A Aguilar
Publikováno v:
eLife, Vol 12 (2023)
The acute traumatic or surgical loss of skeletal muscle, known as volumetric muscle loss (VML), is a devastating type of injury that results in exacerbated and persistent inflammation followed by fibrosis. The mechanisms that mediate the magnitude an
Externí odkaz:
https://doaj.org/article/31581a1de5ad4f9382524e610ca6c880
Autor:
Randall F. D'Souza, Vandre C. Figueiredo, James F. Markworth, Nina Zeng, Christopher P. Hedges, Llion A. Roberts, Truls Raastad, Jeff S. Coombes, Jonathan M. Peake, Cameron J. Mitchell, David Cameron‐Smith
Publikováno v:
Physiological Reports, Vol 11, Iss 15, Pp n/a-n/a (2023)
Abstract Cold water immersion (CWI) following intense exercise is a common athletic recovery practice. However, CWI impacts muscle adaptations to exercise training, with attenuated muscle hypertrophy and increased angiogenesis. Tissue temperature mod
Externí odkaz:
https://doaj.org/article/d4749583231e4aa299375a45a732ef07
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a227545c248c4de4b98f4a4d49d91563
Autor:
Vandré C. Figueiredo, Randall F. D'Souza, Douglas W. Van Pelt, Marcus M. Lawrence, Nina Zeng, James F. Markworth, Sally D. Poppitt, Benjamin F. Miller, Cameron J. Mitchell, John J. McCarthy, Esther E. Dupont‐Versteegden, David Cameron‐Smith
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 12, Iss 1, Pp 130-143 (2021)
Abstract Background Translational capacity (i.e. ribosomal mass) is a key determinant of protein synthesis and has been associated with skeletal muscle hypertrophy. The role of translational capacity in muscle atrophy and regrowth from disuse is larg
Externí odkaz:
https://doaj.org/article/738d05f29a7246dfb04060da7a14eb4e
Autor:
Steve D. Guzman, Jennifer Judge, Shahjahan M. Shigdar, Thomas A. Paul, Carol S. Davis, Peter C. Macpherson, James F. Markworth, Holly Van Remmen, Arlan Richardson, Anne McArdle, Susan V. Brooks
Publikováno v:
Frontiers in Aging, Vol 2 (2022)
Aging results in the progressive accumulation of senescent cells in tissues that display loss of proliferative capacity and acquire a senescence-associated secretory phenotype (SASP). The tumor suppressor, p16INK4A, which slows the progression of the
Externí odkaz:
https://doaj.org/article/624eb338e7c1447186d014f1dd94f006
Autor:
Jacqueline A Larouche, Mahir Mohiuddin, Jeongmoon J Choi, Peter J Ulintz, Paula Fraczek, Kaitlyn Sabin, Sethuramasundaram Pitchiaya, Sarah J Kurpiers, Jesus Castor-Macias, Wenxuan Liu, Robert Louis Hastings, Lemuel A Brown, James F Markworth, Kanishka De Silva, Benjamin Levi, Sofia D Merajver, Gregorio Valdez, Joe V Chakkalakal, Young C Jang, Susan V Brooks, Carlos A Aguilar
Publikováno v:
eLife, Vol 10 (2021)
During aging and neuromuscular diseases, there is a progressive loss of skeletal muscle volume and function impacting mobility and quality of life. Muscle loss is often associated with denervation and a loss of resident muscle stem cells (satellite c
Externí odkaz:
https://doaj.org/article/1102e70e73174fe0b033c99e67010a4a
Autor:
James F. Markworth, Lemuel A. Brown, Eunice Lim, Carolyn Floyd, Jacqueline Larouche, Jesus A. Castor-Macias, Kristoffer B. Sugg, Dylan C. Sarver, Peter C.D. Macpherson, Carol Davis, Carlos A. Aguilar, Krishna Rao Maddipati, Susan V. Brooks
Publikováno v:
JCI Insight, Vol 5, Iss 18 (2020)
Specialized proresolving mediators (SPMs) actively limit inflammation and expedite its resolution by modulating leukocyte recruitment and function. Here we profiled intramuscular lipid mediators via liquid chromatography-tandem mass spectrometry–ba
Externí odkaz:
https://doaj.org/article/0c793e0487a74a72877e5b31113c104c
Autor:
Anna Shcherbina, Jacqueline Larouche, Paula Fraczek, Benjamin A. Yang, Lemuel A. Brown, James F. Markworth, Carolina H. Chung, Mehwish Khaliq, Kanishka de Silva, Jeongmoon J. Choi, Mohammad Fallahi-Sichani, Sriram Chandrasekaran, Young C. Jang, Susan V. Brooks, Carlos A. Aguilar
Publikováno v:
Cell Reports, Vol 32, Iss 4, Pp 107964- (2020)
Summary: During aging, there is a progressive loss of volume and function in skeletal muscle that impacts mobility and quality of life. The repair of skeletal muscle is regulated by tissue-resident stem cells called satellite cells (or muscle stem ce
Externí odkaz:
https://doaj.org/article/4c25cc2531574597b3eba84ef930cfd5
Autor:
Jonathan M. Peake, James F. Markworth, Kristoffer Toldnes Cumming, Sigve N. Aas, Llion A. Roberts, Truls Raastad, David Cameron-Smith, Vandre C. Figueiredo
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Regular postexercise cooling attenuates muscle hypertrophy, yet its effects on the key molecular factors that regulate muscle growth and remodeling are not well characterized. In the present study, nine men completed two sessions of single-leg resist
Externí odkaz:
https://doaj.org/article/31ad60dbf0d34202b0cff2cea2d022bf
Autor:
Malina D. Doynova, James F. Markworth, David Cameron-Smith, Mark H. Vickers, Justin M. O’Sullivan
Publikováno v:
Skeletal Muscle, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Background The spatial organization of eukaryotic genomes facilitates and reflects the underlying nuclear processes that are occurring in the cell. As such, the spatial organization of a genome represents a window on the genome biology that
Externí odkaz:
https://doaj.org/article/ad91ac8190944e4683d317ca0f751f77