Výsledky vyhledávání - "James F. M. Myers"

Akademický článek

Using Baclofen to Explore GABA-B Receptor Function in Alcohol Dependence: Insights From Pharmacokinetic and Pharmacodynamic Measures

Autor: Claire F. Durant, Louise M. Paterson, Sam Turton, Susan J. Wilson, James F. M. Myers, Suresh Muthukumaraswamy, Ashwin Venkataraman, Inge Mick, Susan Paterson, Tessa Jones, Limon K. Nahar, Rosa E. Cordero, David J. Nutt, Anne Lingford-Hughes

Publikováno v: Frontiers in Psychiatry, Vol 9 (2018)

Background: The role of GABA-B neurotransmission in addiction has recently received increased attention, with clinical trials indicating that baclofen, a GABA-B receptor agonist, may reduce alcohol consumption, craving and promote abstinence. However

Externí odkaz: https://doaj.org/article/b7a7f1523dd8436cba5c44f089043865

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Measurement of GABA using J-difference edited 1H-MRS following modulation of synaptic GABA concentration with tiagabine

Autor: James F M, Myers, C John, Evans, Nicola J, Kalk, Richard A E, Edden, Anne R, Lingford-Hughes

Publikováno v: Synapse (New York, N.Y.). 68(8)

Though GABA is the major inhibitory neurotransmitter in the brain, involved in a wide variety of brain functions and many neuropsychiatric disorders, its intracellular and metabolic presence provides uncertainty in the interpretation of the GABA sign

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::204192830dc901933d042b420f500550
https://pubmed.ncbi.nlm.nih.gov/24756906

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