Zobrazeno 1 - 10
of 49
pro vyhledávání: '"James F. Hyde"'
Publikováno v:
Pediatric Diabetes. 2:25-29
We previously demonstrated that in patients with type 1 diabetes mellitus (DM), co-therapy with subcutaneous (s.c.) recombinant human insulin-like growth factor I (rhIGF-I) and insulin improves glycemic control and reduces daily insulin requirements
Publikováno v:
Pediatric Diabetes. 2:25-29
Publikováno v:
Cell and Tissue Research. 299:185-192
Transgenic mice in which overexpression of the transforming growth factor alpha (TGF-alpha) gene was directed by the keratin-14 promoter were used to study the regulation of cell cycle progression and proliferation in vivo in the olfactory epithelium
Autor:
James F. Hyde, Lydia A. Arbogast
Publikováno v:
Neuroendocrinology. 71:219-227
The purpose of this study was to evaluate interactions between estradiol and the 3′,5′ cyclic adenosine monophosphate (cAMP) signaling pathway to regulate tyrosine hydroxylase (TH) activity in hypothalamic dopaminergic neurons. The first experime
Autor:
Aihua Cai, James F. Hyde, Lydia A. Arbogast, Mary Ellen Hostettler, Joseph P. Moore, James L. Voogt
Publikováno v:
Endocrinology. 141:81-90
The human GH-releasing hormone (hGHRH) transgenic mouse has a hyperplastic anterior pituitary gland that eventually develops into an adenoma. We showed previously that the number of lactotrophs in the male hGHRH transgenic mouse is increased 2-fold,
Publikováno v:
Endocrinology. 140:4955-4964
We generated transgenic mice that carry 4.6 kb of the mouse galanin gene fused to 2.5 kb of the rat PRL promoter. In all transgenic lines that carried and transmitted the transgene, there were significant increases in galanin messenger RNA and peptid
Autor:
Aihua Cai, James F. Hyde
Publikováno v:
Endocrinology. 140:3609-3614
We reported previously an increase in leptin receptor (OBR) gene expression in the anterior pituitary of human GH-releasing hormone (hGHRH) transgenic mice. The primary goal of this study was to investigate the possible mechanisms regulating OBR expr
Publikováno v:
Endocrinology. 139:2452-2458
Estrogen is a robust stimulator of galanin synthesis and secretion in the anterior pituitary. Galanin is colocalized in lactotrophs in the estrogen-treated anterior pituitary, and its roles in lactotroph function are still being elucidated. In the pr
Publikováno v:
Endocrinology. 138:4649-4656
Regulation of galanin gene expression in the anterior pituitary (AP) is positively influenced by estrogen in rodents and undetermined in humans. The objective of this study was to investigate the mechanism behind estrogen induction of galanin by iden
Autor:
Mary Vore, Saul J. Karpen, Michelle O'Brien, Tanmoy C. Ganguly, Fredrick J. Suchy, James F. Hyde
Publikováno v:
Journal of Clinical Investigation. 99:2906-2914
The intracellular mechanism(s) underlying the upregulation of the hepatic Na+/taurocholate cotransporting polypeptide (ntcp) by prolactin (PRL) are unknown. In this report, we demonstrate a time-dependent increase in nuclear translocation of phosphor