Zobrazeno 1 - 10
of 59
pro vyhledávání: '"James F. Eliason"'
Autor:
James F. Eliason, Samir A. Al Hasan, Lance K. Heilbrun, Michael L. Cher, Brenda Dickow, S. Marur, Ulka N. Vaishampayan, Daryn Smith
Publikováno v:
Journal of Urology. 182:317-323
Synergy is observed with the combination of capecitabine and docetaxel due to docetaxel mediated up-regulation of thymidine phosphorylase. A phase II trial was performed with the combination for metastatic, castrate resistant prostate cancer.Eligible
Publikováno v:
Journal of Biomedical Materials Research Part A. :98-107
In vitro expansion of hematopoietic stem cells (HSCs) has been employed to obtain sufficient numbers of stem cells for successful engraftment after HSC transplantation. A three-dimensional perfusion bioreactor system with a heparin-chitosan scaffold
Publikováno v:
Journal of Histochemistry & Cytochemistry. 55:25-33
The protooncogene product HER-2/ neu is the target of the humanized monoclonal antibody trastuzumab (Herceptin). Several tests are used clinically to identify patients with HER-2/ neu overexpression based on evaluation by pathologists of gene amplifi
Publikováno v:
Cytometry Part A. :62-71
Background The enzymes thymidine phosphorylase (TP) and dihydropyrimidine dehydrogenase (DPD) influence the activities of fluoropyrimidine anticancer drugs. The sensitivity of cancer cells to capecitabine, which is an oral, tumor-selective pre-prodru
Autor:
Manabu Fukumoto, Atsuko Kanzaki, Hitoshi Miyashita, James F. Eliason, Takafumi Uchida, Shin Ichi Watanabe, Yuji Takebayashi, Hiroko Bando, Masakazu Toi
Publikováno v:
International Journal of Cancer. 97:631-635
Uridine phosphorylase (UPase) and an angiogenic enzyme, thymidine phosphorylase (dThdPase) are involved in degradation of the pyrimidine nucleosides through phosphorolysis. The expression levels of UPase and dThdPase are higher in human solid tumors
Autor:
James F. Eliason, Zsolt Bacsó
Publikováno v:
Cytometry. 45:180-186
Background Phosphatidylserine (PS) binding by annexin V (AV) is an early membrane marker of apoptosis. Using laser scanning cytometry (LSC) and the comet assay, we showed that the DNA of AV+ cells is so highly fragmented that it cannot be quantified
Autor:
James F. Eliason, Rhonda H. Nicholson, Sarah Weiler, Minoru S.H. Ko, Mark R. Hughes, Joseph Kaplan, Anne Galy, Serafino Pantano
Publikováno v:
Genomics. 68:13-21
Phemx (Pan hematopoietic expression) is a novel murine gene expressed in developmentally regulated sites of hematopoiesis from early in embryogenesis through adulthood. Phemx is expressed in hematopoietic progenitors and mature cells of the three mai
Autor:
Gregory P. Kalemkerian, Muhammad Ali, Antal Orosz, James F. Eliason, Rita Rosati, Mohammed R. Adil, Ferenc Sebestyén
Publikováno v:
Peptides. 19:1519-1523
Small cell lung cancer (SCLC) cells express a variety of neuropeptides which act as autocrine growth factors. Although several neuropeptide analogs have been reported to antagonize SCLC proliferation, the development of these compounds has been limit
Autor:
James F. Eliason
Publikováno v:
Asia-Pacific Biotech News. 10:552-554
Down-regulation of mitochondrial gene expression by the anti-tumor arotinoid mofarotene (Ro 40-8757)
Publikováno v:
International Journal of Cancer. 58:891-897
To understand the mechanism of action of the antitumor arotinoid mofarotene (Ro 40-8757), differential screening of cDNA libraries with cDNA probes prepared from treated or untreated breast-cancer cells was performed. Several genes were identified th