Zobrazeno 1 - 10
of 116
pro vyhledávání: '"James F. Curtin"'
Autor:
Alessandro Cazzolla, Julie Rose Mae Mondala, Janith Wanigasekara, Joanna Carroll, Noah Daly, Brijesh Tiwari, Alan Casey, James F. Curtin
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/15e6d6bf1e7a48f5a4a1c33ddd682e9a
Publikováno v:
PLoS ONE, Vol 18, Iss 2 (2023)
Three-dimensional (3D) cell culture models can help bridge the gap between in vitro cell cultures and in vivo responses by more accurately simulating the natural in vivo environment, shape, tissue stiffness, stressors, gradients and cellular response
Externí odkaz:
https://doaj.org/article/f476473ae8f24a6b8a9e694ee561c566
Autor:
Apurva D. Patange, Jeremy C. Simpson, James F. Curtin, Catherine M. Burgess, P. J. Cullen, Brijesh K. Tiwari
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Biofilms are complex microbial communities that present serious contamination risks to our environment and health. In this study, atmospheric air plasma and airborne acoustic ultrasound technology were applied to inactivate Escherichia coli
Externí odkaz:
https://doaj.org/article/f254772cb4d14fde8f0f557f977d2873
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 6050-6063 (2021)
The G-protein coupled receptor, GPR120, has ubiquitous expression and multifaceted roles in modulating metabolic and anti-inflammatory processes. Recent implications of its role in cancer progression have presented GPR120 as an attractive oncogenic d
Externí odkaz:
https://doaj.org/article/fcf19c2399204e4fa659764299d2f8fb
Autor:
Yinghao Li, Zhonglei He, Jing Lyu, Xianqing Wang, Bei Qiu, Irene Lara-Sáez, Jing Zhang, Ming Zeng, Qian Xu, Sigen A, James F. Curtin, Wenxin Wang
Publikováno v:
Nanomaterials, Vol 12, Iss 21, p 3892 (2022)
Many polymeric gene delivery nano-vectors with hyperbranched structures have been demonstrated to be superior to their linear counterparts. The higher delivery efficacy is commonly attributed to the abundant terminal groups of branched polymers, whic
Externí odkaz:
https://doaj.org/article/80f25149837d4d858c773eed09617a31
Autor:
Gillian E. Conway, Deimante Zizyte, Julie Rose Mae Mondala, Zhonglei He, Lorna Lynam, Mathilde Lecourt, Carlos Barcia, Orla Howe, James F. Curtin
Publikováno v:
Pharmaceuticals, Vol 14, Iss 2, p 91 (2021)
Ursolic acid (UA) is a bioactive compound which has demonstrated therapeutic efficacy in a variety of cancer cell lines. UA activates various signalling pathways in Glioblastoma multiforme (GBM) and offers a promising starting point in drug discovery
Externí odkaz:
https://doaj.org/article/67ee332c7fca43b59dfb35408e8ba7fc
Autor:
Marianela Candolfi, Gwendalyn D. King, Kader Yagiz, James F. Curtin, Yohei Mineharu, AKM Ghulam Muhammad, David Foulad, Kurt M. Kroeger, Nick Barnett, Regis Josien, Pedro R. Lowenstein, Maria G. Castro
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 14, Iss 8, Pp 757-770 (2012)
Adenovirus-mediated delivery of the immune-stimulatory cytokine Flt3L and the conditionally cytotoxic thymidine kinase (TK) induces tumor regression and long-term survival in preclinical glioma (glioblastoma multiforme [GBM]) models. Flt3L induces ex
Externí odkaz:
https://doaj.org/article/48055997b2cf415fbca0be0e9b4482d5
Autor:
Marianela Candolfi, James F. Curtin, Kader Yagiz, Hikmat Assi, Mia K. Wibowo, Gabrielle E. Alzadeh, David Foulad, AKM G. Muhammad, Sofia Salehi, Naomi Keech, Mariana Puntel, Chunyan Liu, Nicholas R. Sanderson, Kurt M. Kroeger, Robert Dunn, Gislaine Martins, Pedro R. Lowenstein, Maria G. Castro
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 10, Pp 947-960 (2011)
We have demonstrated that modifying the tumor microenvironment through intratumoral administration of adenoviral vectors (Ad) encoding the conditional cytotoxic molecule, i.e., HSV1-TK and the immune-stimulatory cytokine, i.e., fms-like tyrosine kina
Externí odkaz:
https://doaj.org/article/4527ff1271c44c6f9dfe80d357ebd9d0
Autor:
Patrick J. Cullen, Janith Wanigasekara, Brijesh K. Tiwari, Andressa Maria Aguiar de Carvalho, James F. Curtin
Publikováno v:
Articles
Various complex biological effects occur when ultrasonic compression waves travel through biological material. The myriad of biological outcomes instigated by ultrasound are evident when viewed through the lens of the hallmarks of cancer. Herein, we
Autor:
Jing Zhang, Zhonglei He, Yinghao Li, Yu Shen, Guanfu Wu, Laura Power, Rijian Song, Ming Zeng, Xianqing Wang, Irene Lara Sáez, Sigen A, Qian Xu, James F. Curtin, Ziyi Yu, Wenxin Wang
Publikováno v:
Acta Biomaterialia.