Zobrazeno 1 - 10
of 12
pro vyhledávání: '"James F Zobel"'
Autor:
Amanda K. Werle, Thomas W. Powers, James F. Zobel, Caitlin N. Wappelhorst, Martin F. Jarrold, Nicholas A. Lyktey, Courtney D.K. Sloan, Andrew J. Wolf, Sharee Adams-Hall, Phoebe Baldus, Herbert A. Runnels
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 254-262 (2021)
Adeno-associated virus (AAV) vectors, which contain a DNA transgene packaged into a protein capsid, have shown tremendous therapeutic potential in recent years. An inherent characteristic of the manufacturing process is production of empty capsids th
Externí odkaz:
https://doaj.org/article/183778a5da634cf8b499c6c5e5ca2a12
Autor:
Andrew J. Wolf, Martin F. Jarrold, Amanda K. Werle, Nicholas A. Lyktey, Sharee B. Adams-Hall, Herbert A. Runnels, Phoebe Baldus, James F. Zobel, Caitlin N. Wappelhorst, Courtney D.K. Sloan, Thomas W. Powers
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 254-262 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Adeno-associated virus (AAV) vectors, which contain a DNA transgene packaged into a protein capsid, have shown tremendous therapeutic potential in recent years. An inherent characteristic of the manufacturing process is production of empty capsids th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a82d22693567f7b6df047326f40e7c3
http://www.sciencedirect.com/science/article/pii/S2329050121001352
http://www.sciencedirect.com/science/article/pii/S2329050121001352
Autor:
James F. Zobel, Libbey Anne Yates, Jennifer Marie Thorn, Colleen Isele, Michael J. McCluskie, Keshab Bhattacharya, Justin B. Sperry, Renata Crutcher, Barbara Kelly, Ningli Zhang, Heather L. Davis
Publikováno v:
Vaccines, Vol 5, Iss 2, p 11 (2017)
Vaccines
Vaccines
Smoking remains one of the major causes of morbidity and mortality worldwide. One approach to assisting smoking cessation is via anti-nicotine vaccines, composed of nicotine-like haptens conjugated to a carrier protein plus adjuvant(s). We have previ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf063813eeefd5f8db5218cbd5ada0af
http://www.mdpi.com/2076-393X/5/2/11
http://www.mdpi.com/2076-393X/5/2/11
Autor:
Serdar Aykent, Oliphant Theodore Lawrence, Kristine Wells, Nathan A. Lacher, Sandra Lightle, Vesselin Mitaksov, James F. Zobel
Publikováno v:
Protein Science. 19:753-762
Human IgG2 antibodies may exist in at least three distinct structural isomers due to disulfide shuffling within the upper hinge region. Antibody interactions with Fc gamma receptors and the complement component C1q contribute to immune effector funct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f1ac829771f394ff2a1035d92b6f312
https://doi.org/10.1002/pro.352
https://doi.org/10.1002/pro.352
Autor:
Paul C. Toren, Bernard N. Violand, James F. Zobel, Christine E. Smith, Ned R. Siegel, Billy D. Vineyard, Jacob S. Tou, Paul D. Pyla, Eric W. Kolodziej
Publikováno v:
International Journal of Peptide and Protein Research. 37:463-467
A rapid method for determining the three disulfide bond pairings in bovine transforming growth factor-alpha (bTGF-alpha) was developed by digesting bTGF-alpha with thermolysin followed by separation of the generated peptides by reversed-phase HPLC. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fafc034ad8f7e4f8f89ed17658a4b2f3
https://doi.org/10.1111/j.1399-3011.1991.tb00762.x
https://doi.org/10.1111/j.1399-3011.1991.tb00762.x
Autor:
Theresa Beck, David Kunneman, Charles F. Voliva, Robert Janssen, Ranjani Parthasarathy, Edwin Rowold, Gary W. Lange, Kelly Botwin, Tiffany D. Duffin, James F. Zobel, Stephen C. Lee
Publikováno v:
Biomedical Microdevices. 3:53-59
Antibodies are immune proteins which specifically recognize and bind foreign macromolecules (antigens) and are critical in protective immune responses to viruses and other pathogens. Their exquisite specificity of binding, as well as their relative e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff7a7728ab8cf350ea87004656b44c98
https://doi.org/10.1023/a:1011429404950
https://doi.org/10.1023/a:1011429404950
Autor:
Gregory Weber, Rosonald R. Bell, Mark A. Thiede, Jean S. Beebe, James F. Zobel, Herbert A. Runnels, Jing Min, Douglas Burdette, Carol B. Donovan, Robbin Alpert, Michelle A. Salafia, Jun Zhang, Kudlacz Elizabeth M, Anthony J. Milici, Xu Xu
Publikováno v:
Advances in therapy. 27(3)
CD44 is a cell adhesion molecule believed to play a critical role in T cell and monocyte infiltration in the inflammatory process. The reduction of CD44 expression or its ability to properly interact with its key ligand, hyaluronic acid (HA), inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d75dce72c9dfb0b9091ec28c2a4811e
https://pubmed.ncbi.nlm.nih.gov/20429046
https://pubmed.ncbi.nlm.nih.gov/20429046
Autor:
James F. Zobel, M.A. Cabonce, Bernard N. Violand, Kevin L. Duffin, Jacob S. Tou, Michael R. Schlittler, Paul C. Toren, Eric W. Kolodziej, Christine E. Smith, Ned R. Siegel
Publikováno v:
Protein Science. 1:1634-1641
Aspartate129 in porcine somatotropin was converted into a cyclic imide residue (succinimide) under acidic solution conditions. Reversed-phase high performance liquid chromatography was utilized to isolate and quantitate this altered species, which ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e8dd0516e8986bd504ab466eaeee278
https://doi.org/10.1002/pro.5560011211
https://doi.org/10.1002/pro.5560011211
Autor:
Tze-Chein Wun, Kuniko K Kretzmer, Mark O Palmier, Kathleen C Day, Margaret D Huang, Dean J Welsch, Charles Lewis, Richard A Wolfe, James F Zobel, Gary W Lange, Ronald B Frazier, Gary S Bild, Michelle A Peel, Robert E Shell, Nancy A Horn, Kurt D Junger, Barbara A Foy, Mark E Gustafson, Richard M Leimgruber, William F Novotny, George J Broze, Yvonne E Pyla, Paul J Hippenmeyer, Thomas G Warren
Publikováno v:
Thrombosis and Haemostasis. 68:054-059
SummaryRecombinant tissue factor pathway inhibitor (rTFPI) has been expressed in four mammalian expression systems using human SK hepatoma, mouse C127, baby hamster kidney (BHK), and Chinese hamster ovary (CHO) cells as hosts. On sodium dodecyl sulfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d63389b2c57bc358d4345af1819cf2f
https://doi.org/10.1055/s-0038-1656317
https://doi.org/10.1055/s-0038-1656317
Autor:
Kam Fok, Margaret H. Marino, Troii Hall, Anne-Marie Malfait, Alfredo G. Tomasselli, Min M. Liu, Micky D. Tortorella, James F. Zobel
Publikováno v:
Journal of chromatography. A. 1148(1)
A rapid HPLC assay was developed for monitoring the activity of the two proprotein convertases, PACE-4 and furin. Six novel peptide substrates were synthesized containing the minimal PC recognition sequence (Arg-X-X-Arg), as well as tryptophan residu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::025746b52151cdc0cd0fd12a3b844d42
https://pubmed.ncbi.nlm.nih.gov/17391681
https://pubmed.ncbi.nlm.nih.gov/17391681