Zobrazeno 1 - 10
of 89
pro vyhledávání: '"James F Sanchez"'
Autor:
Zhen Han, Xiwei Wu, Hanjun Qin, Yate-Ching Yuan, Daniel Schmolze, Chingyu Su, Jasmine Zain, Lilach Moyal, Emmilia Hodak, James F. Sanchez, Peter P. Lee, Mingye Feng, Steven T. Rosen, Christiane Querfeld
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Cutaneous T cell lymphoma (CTCL) is a disfiguring and incurable disease characterized by skin-homing malignant T cells surrounded by immune cells that promote CTCL growth through an immunosuppressive tumor microenvironment (TME). Preliminary data fro
Externí odkaz:
https://doaj.org/article/aea90ab340bd4aec9702c4b9ba05a095
Autor:
Jayeeta Ghose, Ada Dona, Mariam Murtadha, Emine Gulsen Gunes, Enrico Caserta, Ji Young Yoo, Luke Russell, Alena Cristina Jaime-Ramirez, Benjamin G. Barwick, Vikas A. Gupta, James F. Sanchez, Douglas W. Sborov, Steven T. Rosen, Amrita Krishnan, Lawrence H. Boise, Balveen Kaur, Craig C. Hofmeister, Flavia Pichiorri
Publikováno v:
Molecular Therapy: Oncolytics, Vol 20, Iss , Pp 519-531 (2021)
Because most patients with multiple myeloma (MM) develop resistance to current regimens, novel approaches are needed. Genetically modified, replication-competent oncolytic viruses exhibit high tropism for tumor cells regardless of cancer stage and pr
Externí odkaz:
https://doaj.org/article/65d17a0839584df484a779e3dc1740bf
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Multiple myeloma (MM) is a cancer of terminally differentiated plasma cells (PCs) that develop at multiple sites within the bone marrow (BM). MM is treatable but rarely curable because of the frequent emergence of drug resistance and relapse. Increas
Externí odkaz:
https://doaj.org/article/163b391628ea4d06b39718434674d918
Autor:
Ralf Buettner, Corey Morales, Xiwei Wu, James F. Sanchez, Hongzhi Li, Laleh G. Melstrom, Steven T. Rosen
Publikováno v:
Molecular Therapy: Oncolytics, Vol 14, Iss , Pp 149-158 (2019)
The immunosuppressive agent leflunomide has been used in the treatment of over 300,000 patients with rheumatoid arthritis. Its active metabolite, teriflunomide (Ter), directly inhibits dihydroorotate dehydrogenase (DHODH), an enzyme involved in nucle
Externí odkaz:
https://doaj.org/article/7c54185b871c42849daed3aecfbbae7e
Autor:
Stephen J. Forman, Amrita Y. Krishnan, Myo Htut, Flavia Pichiorri, Christine E. Brown, Lu Yang, James F. Sanchez, Sandra H. Thomas, Wen-Chung Chang, ChingLam W. Wong, Laura Lim, Christian Huynh, Lihong Weng, Ryan Urak, Miriam Walter, Xiuli Wang
Taqman probes used in qPCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7246d92a50b759a9b44e0b824f4f0ad9
https://doi.org/10.1158/1078-0432.22462811
https://doi.org/10.1158/1078-0432.22462811
Autor:
Stephen J. Forman, Amrita Y. Krishnan, Myo Htut, Flavia Pichiorri, Christine E. Brown, Lu Yang, James F. Sanchez, Sandra H. Thomas, Wen-Chung Chang, ChingLam W. Wong, Laura Lim, Christian Huynh, Lihong Weng, Ryan Urak, Miriam Walter, Xiuli Wang
Supplemental Figure 1. High dose CS1 CAR T cells were not able to prevent tumor relapse Supplemental Figure 2. Soluble CS1 does not interfere with CS1 CAR function Supplemental Figure 3. Lenalidomide preferentially expanded CD8+CAR+ T cells in a dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bf184f1475c502d8018eaebbb3e3d3
https://doi.org/10.1158/1078-0432.22462814.v1
https://doi.org/10.1158/1078-0432.22462814.v1
Autor:
Stephen J. Forman, Amrita Y. Krishnan, Myo Htut, Flavia Pichiorri, Christine E. Brown, Lu Yang, James F. Sanchez, Sandra H. Thomas, Wen-Chung Chang, ChingLam W. Wong, Laura Lim, Christian Huynh, Lihong Weng, Ryan Urak, Miriam Walter, Xiuli Wang
DAVID Functional annotation analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c378a2be3f96d3af0c8d25228cfe934
https://doi.org/10.1158/1078-0432.22462802.v1
https://doi.org/10.1158/1078-0432.22462802.v1
Autor:
Stephen J. Forman, Amrita Y. Krishnan, Myo Htut, Flavia Pichiorri, Christine E. Brown, Lu Yang, James F. Sanchez, Sandra H. Thomas, Wen-Chung Chang, ChingLam W. Wong, Laura Lim, Christian Huynh, Lihong Weng, Ryan Urak, Miriam Walter, Xiuli Wang
Up-regulated genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a6114800c20cada2e1c4fee8275db7
https://doi.org/10.1158/1078-0432.22462808.v1
https://doi.org/10.1158/1078-0432.22462808.v1
Autor:
Stephen J. Forman, Amrita Y. Krishnan, Myo Htut, Flavia Pichiorri, Christine E. Brown, Lu Yang, James F. Sanchez, Sandra H. Thomas, Wen-Chung Chang, ChingLam W. Wong, Laura Lim, Christian Huynh, Lihong Weng, Ryan Urak, Miriam Walter, Xiuli Wang
Purpose: Multiple myeloma remains an incurable malignancy of plasma cells despite considerable advances in treatment. The purpose of the study was to develop novel chimeric antigen receptors (CAR) for the treatment of multiple myeloma and explore com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001a0842536a55372fea3c5e6bb28f41
https://doi.org/10.1158/1078-0432.c.6525215.v1
https://doi.org/10.1158/1078-0432.c.6525215.v1
Autor:
Stephen J. Forman, Amrita Y. Krishnan, Myo Htut, Flavia Pichiorri, Christine E. Brown, Lu Yang, James F. Sanchez, Sandra H. Thomas, Wen-Chung Chang, ChingLam W. Wong, Laura Lim, Christian Huynh, Lihong Weng, Ryan Urak, Miriam Walter, Xiuli Wang
Down-regulated genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309f2c1a8ced2ed142164e6ed5c3f1b1
https://doi.org/10.1158/1078-0432.22462805.v1
https://doi.org/10.1158/1078-0432.22462805.v1