Zobrazeno 1 - 10
of 363
pro vyhledávání: '"James F Martin"'
Autor:
Hsin-I Jen, Matthew C Hill, Litao Tao, Kuanwei Sheng, Wenjian Cao, Hongyuan Zhang, Haoze V Yu, Juan Llamas, Chenghang Zong, James F Martin, Neil Segil, Andrew K Groves
Publikováno v:
eLife, Vol 8 (2019)
The mammalian cochlea loses its ability to regenerate new hair cells prior to the onset of hearing. In contrast, the adult vestibular system can produce new hair cells in response to damage, or by reprogramming of supporting cells with the hair cell
Externí odkaz:
https://doaj.org/article/627c72e39e6e4cba80400a301229c433
Autor:
Zhao Sun, Clarissa S G da Fontoura, Myriam Moreno, Nathan E Holton, Mason Sweat, Yan Sweat, Myoung Keun Lee, Jed Arbon, Felicitas B Bidlack, Daniel R Thedens, Peggy Nopoulos, Huojun Cao, Steven Eliason, Seth M Weinberg, James F Martin, Lina Moreno-Uribe, Brad A Amendt
Publikováno v:
PLoS Genetics, Vol 14, Iss 10, p e1007675 (2018)
The mechanisms that regulate post-natal growth of the craniofacial complex and that ultimately determine the size and shape of our faces are not well understood. Hippo signaling is a general mechanism to control tissue growth and organ size, and alth
Externí odkaz:
https://doaj.org/article/f406ff41219a4b4a9b1fd11bfa23a158
Autor:
Camille Charoy, Sarah Dinvaut, Yohan Chaix, Laurette Morlé, Isabelle Sanyas, Muriel Bozon, Karine Kindbeiter, Bénédicte Durand, Jennifer M Skidmore, Lies De Groef, Motoaki Seki, Lieve Moons, Christiana Ruhrberg, James F Martin, Donna M Martin, Julien Falk, Valerie Castellani
Publikováno v:
eLife, Vol 6 (2017)
The diaphragm muscle is essential for breathing in mammals. Its asymmetric elevation during contraction correlates with morphological features suggestive of inherent left–right (L/R) asymmetry. Whether this asymmetry is due to L versus R difference
Externí odkaz:
https://doaj.org/article/c54bf742fcde4492af26ee2d1304e795
Autor:
Mashrur Ahmed Yafi, Md. Hasibul Husain Hisham, Francisco Grisanti, James F. Martin, Atif Rahman, Md. Abul Hassan Samee
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-17 (2024)
Abstract A critical challenge of single-cell spatial transcriptomics (sc-ST) technologies is their panel size. Being based on fluorescence in situ hybridization, they are typically limited to panels of about a thousand genes. This constrains research
Externí odkaz:
https://doaj.org/article/5a6db1aa711c4b0fa1cb3075008b7125
Autor:
Yu-Jung Tseng, Yuki Kageyama, Rebecca L. Murdaugh, Ayumi Kitano, Jong Hwan Kim, Kevin A. Hoegenauer, Jonathan Tiessen, Mackenzie H. Smith, Hidetaka Uryu, Koichi Takahashi, James F. Martin, Md Abul Hassan Samee, Daisuke Nakada
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Hematopoietic stem cells (HSCs) are capable of regenerating the blood system, but the instructive cues that direct HSCs to regenerate particular lineages lost to the injury remain elusive. Here, we show that iron is increasingly taken up by
Externí odkaz:
https://doaj.org/article/e2f9fc0f56c34621b4e2cc5d8cfc94a7
Autor:
Ge Tao, James F Martin
Publikováno v:
eLife, Vol 2 (2013)
A microRNA regulates the expression of a network of genes in the heart to ensure that progenitor cells develop into strongly contractile cardiac muscle.
Externí odkaz:
https://doaj.org/article/a752da6eb1b346788f677479bde3af33
Autor:
Yaling Dou, Yan Zhang, Logan Rivera, Tingting Hong, Shaohai Fang, Thuy Tien Tran, Yubin Zhou, James F. Martin, Yun Huang
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 6, Pp n/a-n/a (2024)
Abstract Background Myeloid cells play critical roles in the regulation of myocardial injury and repair. Clonal hematopoiesis (CH)‐related mutations in genes, such as Ten‐eleven Translocation 2 (TET2), can impair myeloid cells and are associated
Externí odkaz:
https://doaj.org/article/09a0c5d803c34ffaba37b40f8de2393e
Autor:
Jun Wang, Yan Bai, Hong Li, Stephanie B Greene, Elzbieta Klysik, Wei Yu, Robert J Schwartz, Trevor J Williams, James F Martin
Publikováno v:
PLoS Genetics, Vol 9, Iss 9, p e1003785 (2013)
Among the most common human congenital anomalies, cleft lip and palate (CL/P) affects up to 1 in 700 live births. MicroRNA (miR)s are small, non-coding RNAs that repress gene expression post-transcriptionally. The miR-17-92 cluster encodes six miRs t
Externí odkaz:
https://doaj.org/article/9a295d38ba574972bbee7701823ca1cd
Publikováno v:
J Mol Cell Cardiol
Cardiomyocytes are differentiated heart muscle cells with minimal self-renewal ability. Thus, loss of cardiomyocytes from cardiovascular disease and injury cannot be effectively replenished. Recent studies in animal models have indicated that inducti
Autor:
Alexandria M. Doerfler, Jun Han, Kelsey E. Jarrett, Li Tang, Antrix Jain, Alexander Saltzman, Marco De Giorgi, Marcel Chuecos, Ayrea E. Hurley, Ang Li, Pauline Morand, Claudia Ayala, David R. Goodlett, Anna Malovannaya, James F. Martin, Thomas Q. de Aguiar Vallim, Noah Shroyer, William R. Lagor
Publikováno v:
Arterioscler Thromb Vasc Biol
Background: The intestine occupies the critical interface between cholesterol absorption and excretion. Surprisingly little is known about the role of de novo cholesterol synthesis in this organ, and its relationship to whole body cholesterol homeost