Zobrazeno 1 - 10
of 116
pro vyhledávání: '"James F Curtin"'
Autor:
Alessandro Cazzolla, Julie Rose Mae Mondala, Janith Wanigasekara, Joanna Carroll, Noah Daly, Brijesh Tiwari, Alan Casey, James F Curtin
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0300467 (2024)
Liposome nanoparticles can carry a wide range of therapeutic molecules including small molecules and nucleic acid-based therapeutics. Potential benefits include translocation across physiological barriers, reduced systemic toxicity, and enhanced phar
Externí odkaz:
https://doaj.org/article/3b83aeb70f6c452fa1aa3cd0f7c60186
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0276248 (2023)
Three-dimensional (3D) cell culture models can help bridge the gap between in vitro cell cultures and in vivo responses by more accurately simulating the natural in vivo environment, shape, tissue stiffness, stressors, gradients and cellular response
Externí odkaz:
https://doaj.org/article/16018d74e6ea41678fd2dc3e092dc693
Autor:
James F Curtin, Naiyou Liu, Marianela Candolfi, Weidong Xiong, Hikmat Assi, Kader Yagiz, Matthew R Edwards, Kathrin S Michelsen, Kurt M Kroeger, Chunyan Liu, A K M Ghulam Muhammad, Mary C Clark, Moshe Arditi, Begonya Comin-Anduix, Antoni Ribas, Pedro R Lowenstein, Maria G Castro
Publikováno v:
PLoS Medicine, Vol 6, Iss 1, p e10 (2009)
BackgroundGlioblastoma multiforme (GBM) is the most aggressive primary brain tumor that carries a 5-y survival rate of 5%. Attempts at eliciting a clinically relevant anti-GBM immune response in brain tumor patients have met with limited success, whi
Externí odkaz:
https://doaj.org/article/0adb0547db44421eb3369a03d288ff9a
Autor:
James F Curtin, Marianela Candolfi, Tamer M Fakhouri, Chunyan Liu, Anderson Alden, Matthew Edwards, Pedro R Lowenstein, Maria G Castro
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1983 (2008)
Regulatory T lymphocytes (Treg) infiltrate human glioblastoma (GBM); are involved in tumor progression and correlate with tumor grade. Transient elimination of Tregs using CD25 depleting antibodies (PC61) has been found to mediate GBM regression in p
Externí odkaz:
https://doaj.org/article/46b3f6c2f18f483a9fbab5a9a6c65683
Autor:
Patrick J. Cullen, Janith Wanigasekara, Brijesh K. Tiwari, Andressa Maria Aguiar de Carvalho, James F. Curtin
Publikováno v:
Articles
Various complex biological effects occur when ultrasonic compression waves travel through biological material. The myriad of biological outcomes instigated by ultrasound are evident when viewed through the lens of the hallmarks of cancer. Herein, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3b999702f58142b9487df62a3ba17c9
https://doi.org/10.1016/j.trecan.2021.07.004
https://doi.org/10.1016/j.trecan.2021.07.004
Autor:
Jing Zhang, Zhonglei He, Yinghao Li, Yu Shen, Guanfu Wu, Laura Power, Rijian Song, Ming Zeng, Xianqing Wang, Irene Lara Sáez, Sigen A, Qian Xu, James F. Curtin, Ziyi Yu, Wenxin Wang
Publikováno v:
Acta Biomaterialia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c61481427a883e497bac736469f52d
https://doi.org/10.1016/j.actbio.2023.04.041
https://doi.org/10.1016/j.actbio.2023.04.041
Autor:
Maria G. Castro, Pedro R. Lowenstein, Weidong Xiong, Yohei Mineharu, Katsuaki Sato, Jonathan Lerner, Gwendalyn D. King, James F. Curtin, Sharon Lee, Chunyan Liu, Kurt M. Kroeger, Mariana Puntel, A.K.M. Ghulam Muhammad, Matthew Tesarfreund, Gabrielle E. Alzadeh, David Foulad, Kader Yagiz, Marianela Candolfi
Supplementary Data from Release of HMGB1 in Response to Proapoptotic Glioma Killing Strategies: Efficacy and Neurotoxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f6f9ed265063b5a00a088305ff3ba5
https://doi.org/10.1158/1078-0432.22440715.v1
https://doi.org/10.1158/1078-0432.22440715.v1
Publikováno v:
Articles
Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumour in adults. Treatments include surgical resection, radiotherapy, and chemotherapy. Despite this, the prognosis remains poor, with an impacted quality of life during t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793e89f74c0ff6ea595fa413518deb10
https://doi.org/10.1016/j.drudis.2021.07.008
https://doi.org/10.1016/j.drudis.2021.07.008
Publikováno v:
Articles
The aim of this study was to determine the effects of a pin‐to‐plate cold atmospheric plasma (CAP) on U‐251 MG three‐dimensional (3D) glioblastoma spheroids under different conditions. 3D tumorspheres showed higher resistance to the CAP treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3f4ab8463a4f1d497d05adc9d92642
https://arrow.tudublin.ie/creaart/109
https://arrow.tudublin.ie/creaart/109
Publikováno v:
Drug discovery today. 28(2)
This review focuses on recent advances in 3D culture systems that promise more accurate therapeutic models of the glioblastoma multiforme (GBM) tumor microenvironment (TME), such as the unique anatomical, cellular, and molecular features evident in h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d47facd38317856aed2f3b0af3e50d
https://pubmed.ncbi.nlm.nih.gov/36332834
https://pubmed.ncbi.nlm.nih.gov/36332834