Zobrazeno 1 - 10
of 350
pro vyhledávání: '"James E. Turner"'
Autor:
Harrison D. Collier-Bain, Frankie F. Brown, Adam J. Causer, Lois Ross, Daniela Rothschild-Rodriguez, Noah Browne, Rachel Eddy, Kirstie L. Cleary, Juliet C. Gray, Mark S. Cragg, Sally Moore, James Murray, James E. Turner, John P. Campbell
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Complement-dependent cytotoxicity (CDC) is a primary mechanism-of-action of monoclonal antibody (mAb) immunotherapies used to treat haematological cancers, including rituximab and daratumumab. However, mAb efficacy may be limited by reduced
Externí odkaz:
https://doaj.org/article/05c09f05aa634c8b8fd55a17bc92a64f
Autor:
Lucy H. Merrell, Oliver J. Perkin, Louise Bradshaw, Harrison D. Collier‐Bain, Adam J. Collins, Sophie Davies, Rachel Eddy, James A. Hickman, Anna P. Nicholas, Daniel Rees, Bruno Spellanzon, Lewis J. James, Alannah K. A. McKay, Harry A. Smith, James E. Turner, Francoise Koumanov, Jennifer Maher, Dylan Thompson, Javier T. Gonzalez, James A. Betts
Publikováno v:
Experimental Physiology, Vol 109, Iss 7, Pp 1099-1108 (2024)
Abstract The premise of research in human physiology is to explore a multifaceted system whilst identifying one or a few outcomes of interest. Therefore, the control of potentially confounding variables requires careful thought regarding the extent o
Externí odkaz:
https://doaj.org/article/8c1ee43dcc1a43ec822486a26db8c0d7
Autor:
Britta Stordal, Michelle Harvie, Michael N. Antoniou, Michelle Bellingham, Doris S. M. Chan, Philippa Darbre, Oskar Karlsson, Andreas Kortenkamp, Pamela Magee, Stefano Mandriota, Elisabete Silva, James E. Turner, Laura N. Vandenberg, D. Gareth Evans
Publikováno v:
Cancer Medicine, Vol 13, Iss 18, Pp n/a-n/a (2024)
Abstract The Breast Cancer UK—Breast Cancer Prevention Conference addressed risk from environmental pollutants and health behaviour‐related breast‐cancer risk. Epidemiological studies examining individual chemicals and breast cancer risk have p
Externí odkaz:
https://doaj.org/article/70c3e2894184461e82f75d07e3fce5a2
Autor:
Harrison D. Collier-Bain, Annabelle Emery, Frankie F. Brown, Adam J. Causer, Rebecca Oliver, Rachel Eddy, Shoji Leach, John Graby, Daniel Augustine, Sally Moore, Josephine Crowe, James Murray, James E. Turner, John P. Campbell
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 42, Iss , Pp 100865- (2024)
Multiple myeloma is a haematological cancer characterised by the accumulation of clonal plasma cells in the bone marrow and is commonly treated with daratumumab, an anti-CD38 monoclonal antibody immunotherapy. Daratumumab often fails to induce string
Externí odkaz:
https://doaj.org/article/6afa8708b3024e63913bbe863221bf42
Autor:
Harrison D. Collier-Bain, Frankie F. Brown, Adam J. Causer, Annabelle Emery, Rebecca Oliver, Sally Moore, James Murray, James E. Turner, John P. Campbell
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Therapeutic monoclonal antibodies (mAbs) are standard care for many B-cell haematological cancers. The modes of action for these mAbs include: induction of cancer cell lysis by activating Fcγ-receptors on innate immune cells; opsonising target cells
Externí odkaz:
https://doaj.org/article/4fb719a767b54c49a07e03d0de5045f4
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/a3a10de49c7e404a82aa0d13fc9f0fce
Publikováno v:
Frontiers in Aging, Vol 4 (2023)
Externí odkaz:
https://doaj.org/article/3c0f8f940ae349409bed137ae9b7ea5c
Autor:
Ainhoa Arana Echarri, Lauren Struszczak, Mark Beresford, John P. Campbell, Robert H. Jones, Dylan Thompson, James E. Turner
Publikováno v:
Frontiers in Physiology, Vol 14 (2023)
Methods: We examined whether immune cell profiles differ between healthy women (n = 38) and breast cancer survivors (n = 27) within 2 years of treatment, and whether any group-differences were influenced by age, cytomegalovirus infection, cardiorespi
Externí odkaz:
https://doaj.org/article/9e2ef7a3341043debd7f5288d414dd65
Autor:
Ainhoa Arana Echarri, Lauren Struszczak, Mark Beresford, John P. Campbell, Dylan Thompson, James E. Turner
Publikováno v:
Frontiers in Sports and Active Living, Vol 5 (2023)
MethodsThis study examined the effects of exercise training for 8 weeks on blood immune cell characteristics among 20 breast cancer survivors (age 56 ± 6 years, Body Mass Index 25.4 ± 3.0 kg m2) within two years of treatment. Participants were rand
Externí odkaz:
https://doaj.org/article/1c07792efe764e3fa1d7c39ede1ebc54
Autor:
Luiz Augusto Riani Costa, Raphael F. Barreto, Sarah Milani Moraes de Leandrini, Aline Rachel Bezerra Gurgel, Gabriel Toledo de Sales, Vanessa Azevedo Voltarelli, Gilberto de Castro, Sally A. M. Fenton, James E. Turner, Christian Klausener, Lucas Melo Neves, Carlos Ugrinowitsch, Jose Carlos Farah, Cláudia Lúcia de Moraes Forjaz, Christina May Moran Brito, Patricia Chakur Brum
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Most cancer patients, under active treatment or not, are sedentary, despite increasing scientific and clinical understanding of the benefits of exercise and physical activity, such as improving quality of life, limiting disease sy
Externí odkaz:
https://doaj.org/article/162ef7937b8f4d6da9c2ca486af60a60