Zobrazeno 1 - 10
of 24
pro vyhledávání: '"James E. Madl"'
Publikováno v:
Veterinary Ophthalmology. 18:35-42
Objective To investigate the distribution of retinal ganglion cells (RGCs) and visual acuity in alpacas (Vicugna pacos) through Brn-3a immunofluorescent labeling. Procedures Five eyes from four healthy alpacas with normal ophthalmic examination findi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6acb27f1c72694048bd67a25355b2a70
https://doi.org/10.1111/vop.12131
https://doi.org/10.1111/vop.12131
Autor:
Kate S. Freeman, Virginia L. Scofield, James E. Madl, Juliet R. Gionfriddo, Allyson D. Groth, Khaleel Alyahya
Publikováno v:
Veterinary Ophthalmology. 12:325-332
Objective To test the hypothesis that in DBA/2J mice, oxidative stress decreases glutamine synthetase (GS) levels resulting in a loss of neuronal glutamate and that the antioxidant α-luminol (GVT®) decreases this stress and glutamate loss in some t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c3b7f328497299420a1aba9d7c624c
https://doi.org/10.1111/j.1463-5224.2009.00722.x
https://doi.org/10.1111/j.1463-5224.2009.00722.x
Autor:
Khaleel Alyahya, Juliet R. Gionfriddo, Chu-Te Chen, Cynthia C. Powell, Richard R. Dubielzig, E. J. Ehrhart, James E. Madl, Brendan G. Mangan
Publikováno v:
Veterinary Ophthalmology. 10:117-124
Objective This paper aims to determine if abnormalities of the retinal pigment epithelium (RPE) and retinal inflammation occur in primary glaucoma. Procedure Twenty-three canine globes with primary glaucoma, goniodysgenesis, and elevated intraocular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e225bf4d3965dbb75fd40b263f2daa9
https://doi.org/10.1111/j.1463-5224.2007.00585.x
https://doi.org/10.1111/j.1463-5224.2007.00585.x
Autor:
Khaleel Alyahya, Thomas M. Chen, Juliet R. Gionfriddo, Anna N. Novakowski, James E. Madl, Pei-Yi Tai
Publikováno v:
Veterinary ophthalmology. 18(4)
Objective To test the hypothesis that oxidative stress occurs early in the pathogenesis of glaucoma in dogs. Animals Sections from eight control retinas and 25 retinas from dogs with primary glaucoma. Methods For retinas embedded in paraffin, section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be1a166829619da16fa4a82650f3fde6
https://pubmed.ncbi.nlm.nih.gov/24814303
https://pubmed.ncbi.nlm.nih.gov/24814303
Publikováno v:
Aquatic toxicology (Amsterdam, Netherlands). 156
California sea lions (CSLs) exposed to the marine biotoxin domoic acid (DA) develop an acute or chronic toxicosis marked by seizures and act as sentinels of the disease. Experimental evidence suggests that oxidative stress and neuroinflammation are i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d9699f977b2c1a5a7e6f9d489e14dec
https://pubmed.ncbi.nlm.nih.gov/25286249
https://pubmed.ncbi.nlm.nih.gov/25286249
Autor:
James E. Madl, J.E. Stanhill, Colleen Duncan, Terry R. Spraker, Frances M. D. Gulland, P.-Y. Tai
Publikováno v:
Journal of comparative pathology. 150(2-3)
Summary The aim of this study was to test the hypothesis that oxidative stress and glutamine synthetase (GS) redistribution occur in domoic acid (DA) toxicosis in California sea lions (CSLs, Zalophus californianus ). Sections of archived hippocampi f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::578716bb061c01836e358d5dde11b593
https://pubmed.ncbi.nlm.nih.gov/24060152
https://pubmed.ncbi.nlm.nih.gov/24060152
Publikováno v:
Brain research. 1303
The aim of this study was to identify factors that regulate the bulk of adult brain mass, and test the hypothesis that concomitantly reduced insulin and insulin-like growth factor (IGF) levels are pathogenic for brain atrophy associated with impaired
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af78fed76251a49ddb1fc3171fe438f
https://pubmed.ncbi.nlm.nih.gov/19781531
https://pubmed.ncbi.nlm.nih.gov/19781531
Autor:
Richard R. Dubielzig, Juliet R. Gionfriddo, Khaleel Alyahya, Marie E. Legare, Brendan G. Mangan, Chu-Te Chen, James E. Madl
Publikováno v:
Veterinary ophthalmology. 10
Objective Vascular damage and ischemia-like changes in glutamate distribution occur in primary glaucoma (PG) in dogs. We measured the microvessel density in PG retinas to determine whether microvessel loss may induce ischemia and glutamate redistribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d7b5b5c6b5976d1f3b88a9207b5700
https://pubmed.ncbi.nlm.nih.gov/17973837
https://pubmed.ncbi.nlm.nih.gov/17973837
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 91(2)
Chronic exposure to excessive manganese (Mn) is the cause of a neurodegenerative movement disorder, termed manganism, resulting from degeneration of neurons within the basal ganglia. Pathogenic mechanisms underlying this disorder are not fully unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fd2899b39ba3596461c6170f3f625a
https://pubmed.ncbi.nlm.nih.gov/16551646
https://pubmed.ncbi.nlm.nih.gov/16551646
Publikováno v:
American journal of veterinary research. 67(2)
Objective—To determine whether glutamate contents are decreased in the ganglion cell layer (GCL) of retinas of DBA/2J mice with glaucoma, compared with unaffected control mice. Sample Population—20 eyes from DBA/2J mice (9-week-old mice [n = 8] a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7055a1ed50dbe770400c8d6100df3207
https://pubmed.ncbi.nlm.nih.gov/16454637
https://pubmed.ncbi.nlm.nih.gov/16454637