Zobrazeno 1 - 5
of 5
pro vyhledávání: '"James E. Loukides"'
Autor:
Céline Morissette, Patrick Horne, George A. Carlson, Sherry Turner, Christopher Janus, Noah Zuker, Peter St George-Hyslop, David Westaway, Jacqueline Pearson, Paul E. Fraser, Amie L. Phinney, Dun-Shen Yang, Gianluca Lozza, Francine Gervais, Janet French, Suzanne Kunicki, Robert Strome, Mariagrazia Grilli, Catherine Bergeron, M. Azhar Chishti, Julie Paquette, James E. Loukides
Publikováno v:
The Journal of biological chemistry. 276(24)
We have created early-onset transgenic (Tg) models by exploiting the synergistic effects of familial Alzheimer's disease mutations on amyloid beta-peptide (Abeta) biogenesis. TgCRND8 mice encode a double mutant form of amyloid precursor protein 695 (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6adb73849e556254c22670c19acecd8b
https://pubmed.ncbi.nlm.nih.gov/11279122
https://pubmed.ncbi.nlm.nih.gov/11279122
Autor:
James E. Loukides, Neil D. Berman
Publikováno v:
Journal of Electrocardiology. 20:297-302
The addition of propranolol to mexiletine may reduce the adverse effects of mexiletine and possibly increase its efficacy. We compared the cellular electrophysiologic effects of this combination with mexiletine and propranolol alone, over concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97b2f2538c22f52fc0c28cf655bb0863
https://doi.org/10.1016/s0022-0736(87)80080-8
https://doi.org/10.1016/s0022-0736(87)80080-8
Autor:
Neil D. Berman, James E. Loukides
Publikováno v:
Journal of Cardiovascular Pharmacology. 12:286-292
To determine if combinations of mexiletine and sotalol retain Class I and III electrophysiologic actions, using standard microelectrode techniques, we examined the electrophysiologic effects on canine Purkinje fibers of solutions of mexiletine (3.1-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a75fdf3553b45e7eaa6f4b43931532e
https://doi.org/10.1097/00005344-198809000-00005
https://doi.org/10.1097/00005344-198809000-00005
Publikováno v:
Journal of cardiovascular pharmacology. 8(6)
The electropharmacologic effects of an equimolar combination of mexiletine and quinidine on canine Purkinje action potential parameters were compared with the effects of either drug alone in concentrations ranging from 0.31 to 5.0 X 10(-5) M. Six sep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1643cbc585d0686e0a8629985bed9681
https://pubmed.ncbi.nlm.nih.gov/2434738
https://pubmed.ncbi.nlm.nih.gov/2434738
Publikováno v:
Canadian journal of physiology and pharmacology. 65(10)
The persistence of cellular electropharmacologic effects of mexiletine on canine Purkinje fibers was studied utilizing standard microelectrode techniques and two different protocols. In the first, the tissue was exposed to hypoxic perfusion before an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c200cb6e314e41f6b9fe60816680d19
https://pubmed.ncbi.nlm.nih.gov/3427544
https://pubmed.ncbi.nlm.nih.gov/3427544