Zobrazeno 1 - 10
of 137
pro vyhledávání: '"James E. Faber"'
Autor:
Firas eAl-Ali, John J. Elias, Danielle Elizabeth Filipkowski, Ramón eGilberto González, James E. Faber
Publikováno v:
Frontiers in Neurology, Vol 6 (2015)
The current strategy for intra-arterial treatment (IAT) of acute ischemic stroke focuses on minimizing time from ictus to revascularization and maximizing revascularization. Employing this strategy has yet to lead to improved rates of successful outc
Externí odkaz:
https://doaj.org/article/d64b4fc44e0c45129d8b702bdc346338
Autor:
Adnan Khan, Patrick De Boever, Nele Gerrits, Naveed Akhtar, Maher Saqqur, Georgios Ponirakis, Hoda Gad, Ioannis N Petropoulos, Ashfaq Shuaib, James E Faber, Saadat Kamran, Rayaz A Malik
Publikováno v:
PLoS ONE, Vol 17, Iss 5, p e0267837 (2022)
ObjectivesPial collateral blood flow is a major determinant of the outcomes of acute ischemic stroke. This study was undertaken to determine whether retinal vessel metrics can predict the pial collateral status and stroke outcomes in patients.Methods
Externí odkaz:
https://doaj.org/article/12d7016e314349ce95e386677eb35cfc
Autor:
Philipp Hendrix, Nelson Sofoluke, Matthew Adams, Saran Kunaprayoon, Ramin Zand, Amy N Kolinovsky, Thomas N Person, Mudit Gupta, Oded Goren, H Lester Kirchner, Clemens M Schirmer, Natalia S Rost, James E Faber, Christoph J Griessenauer
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0235122 (2020)
The MGP single nucleotide polymorphism (SNP) rs1800801 has previously been associated with recurrent ischemic stroke in a Spanish cohort. Here, we tested for association of this SNP with ischemic stroke recurrence in a North American Caucasian cohort
Externí odkaz:
https://doaj.org/article/31fd421dad4d4b4e89dd48bc4b708f99
Publikováno v:
J Mol Cell Cardiol
Rationale Collateral vessels lessen myocardial ischemia when acute or chronic coronary obstruction occurs. It has long been assumed that although native (pre-existing) collaterals enlarge in obstructive disease, new collaterals do not form in the adu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6718ffad0b937fafd9465ce079129d4
https://doi.org/10.1016/j.yjmcc.2020.09.015
https://doi.org/10.1016/j.yjmcc.2020.09.015
Autor:
Andreia Morais, Tsubasa Takizawa, Yoshinobu Kamio, Yuichi Murayama, James E. Faber, Hua Zhang, Takeshi Yanagisawa, Cenk Ayata, Aman B. Patel, David Y. Chung, Tomoaki Suzuki, Tao Qin
Publikováno v:
Stroke
Background and Purpose: Intracranial aneurysm formation and rupture risk are, in part, determined by genetic factors and sex. To examine their role, we compared 3 mouse strains commonly used in cerebrovascular studies in a model of intracranial aneur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39bca9d42ab7a1c0d60d0bea3784eaa8
https://doi.org/10.1161/strokeaha.120.029651
https://doi.org/10.1161/strokeaha.120.029651
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism
Collateral number/density varies widely in brain and other tissues among strains of Mus musculus mice due to differences in genetic background. Recent studies have shown that prolonged exposure to reduced atmospheric oxygen induces additional collate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2724f06a515fac97c06207f548fe430
http://europepmc.org/articles/PMC7983333
http://europepmc.org/articles/PMC7983333
Autor:
Cheng Zhang, Yuanyuan Zhang, Jennifer Lucitti, Andrea Palos-Jasso, Sebastian Albinsson, Yuan Gao, Yaru Cui, Takahisa Murata, James E Faber, William C Sessa, Jun Yu
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 41
Nogo-B, a member of the reticulon 4 family of proteins, is the dominant isoform expressed in endothelial cells (EC). We have shown that Nogo-B is necessary for blood flow recovery in ischemia. Mice lacking Nogo-B exhibit reduced arteriogenesis and an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc83560028b931ad1dcfece3728ad81d
https://doi.org/10.1161/atvb.41.suppl_1.mp27
https://doi.org/10.1161/atvb.41.suppl_1.mp27
Autor:
Laila Elsherif, Mehmet Ozler, Mohamed A Zayed, Jessica H Shen, Jonathan Chernoff, James E Faber, Leslie V Parise
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112239 (2014)
PAKs are serine/threonine kinases that regulate cytoskeletal dynamics and cell migration. PAK1 is activated by binding to the small EF hand protein, CIB1, or to the Rho GTPases Rac1 or Cdc42. The role of PAK1 in angiogenesis was established based onl
Externí odkaz:
https://doaj.org/article/8976177641be43ec973644d49e4f9d19
Autor:
Martin T. Ferris, Sarah A. Schoenrock, Timothy R. Gershon, David B. Darr, Mark J. Zylka, J. Mauro Calabrese, James E. Faber, Laura G. Reinholdt, David W. Threadgill, John R. Shorter, Kathleen M. Caron, Lisa E. Gralinski, Robert S. Hagan, Glenn K. Matsushima, Yuyu Ren, Christopher M. Sassetti, Christiann H. Gaines, Bin Gu, Lori L. O'Brien, Sheryl S. Moy, Timothy A. Bell, Keegan Wardwell, Barbara J. Vilen, Terry Magnuson, Darla R. Miller, Clare M. Smith, Abraham A. Palmer, A. Wesley Burks, Fernando Pardo-Manuel de Villena, Celine L. St. Pierre, William Valdar, Rachel C. McMullan, Pablo Hock, Frank L. Conlon, Kevin C K Lloyd, Gudrun A. Brockmann, Anwica Kashfeen, Ginger D. Shaw, Steve Rockwood, Karen L. Mohlke, Matthew Blanchard, Alessandra Livraghi-Butrico, Benjamin D. Philpot, Rachel M Lynch, Scott H. Randell, J. Brennan, John Sebastian Sigmon, Vivek Kumar, Ralph S. Baric, Leonard McMillan, Mark T. Heise, Ernest G. Heimsath, Richard E. Cheney, Avani Saraswatula, Lucy H. Williams, Allison R. Rogala, Colton L. Linnertz, Caroline E. Y. Murphy, Dominic Ciavatta, Mike Kulis, Tal Kafri, Craig L. Franklin, Jason K. Whitmire, J. Charles Jennette, Maya L. Najarian, Cathleen M. Lutz, Jonathan C. Schisler, Lisa M. Tarantino, Folami Y. Ideraabdullah
Publikováno v:
Genetics: a periodical record of investigations bearing on heredity and variation, vol 216, iss 4
Genetics
Genetics
The laboratory mouse is the most widely used animal model for biomedical research, due in part to its well-annotated genome, wealth of genetic resources, and the ability to precisely manipulate its genome. Despite the importance of genetics for mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f021d31a7f2e88239f86551bdc6e73b
https://escholarship.org/uc/item/7cq7g4tc
https://escholarship.org/uc/item/7cq7g4tc
Autor:
Christiann H. Gaines, Sheryl S. Moy, Mark T. Heise, Scott H. Randell, Matthew Blanchard, Vivek Kumar, Leonard McMillan, Darla R. Miller, Lucy H. Williams, Timothy A. Bell, Keegan Wardwell, Terry Magnuson, Mark J. Zylka, Christopher M. Sassetti, Craig L. Franklin, Ralph S. Baric, Sarah A. Schoenrock, Glenn K. Matsushima, Cathleen M. Lutz, James E. Faber, Maya L. Najarian, Yuyu Ren, Folami Y. Ideraabdullah, Jason K. Whitmire, Bin Gu, Jonathan C. Schisler, Pablo Hock, J. Charles Jennette, Celine L. St. Pierre, Lisa M. Tarantino, Samir N. P. Kelada, Karen L. Mohlke, Laura G. Reinholdt, Alessandra Livraghi-Butrico, Richard F. Loeser, Abraham A. Palmer, Robert S. Hagan, John R. Shorter, David W. Threadgill, Lori L. O'Brien, Kathleen M. Caron, Steve Rockwood, Kent Lloyd, Fernando Pardo-Manuel de Villena, Caroline E. Y. Murphy, A. Wesley Burks, Tal Kafri, Benjamin D. Philpot, David B. Darr, Avani Saraswatula, Ernest G. Heimsath, Richard E. Cheney, Allison R. Rogala, William Valdar, Dominic Ciavatta, Rachel C. McMullan, Ginger D. Shaw, Clare M. Smith, Frank L. Conlon, Barbara J. Vilen, John Sebastian Sigmon, Gudrun A. Brockmann, Anwica Kashfeen, Martin T. Ferris, Rachel M Lynch, Mauro Calabrese, Colton L. Linnertz, Timothy R. Gershon, J. Brennan, Lisa E. Gralinski, Mike Kulis
The laboratory mouse is the most widely used animal model for biomedical research, due in part to its well annotated genome, wealth of genetic resources and the ability to precisely manipulate its genome. Despite the importance of genetics for mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d2895cb1fd85eea8a9b4a24d854cc2
https://doi.org/10.1101/2020.03.12.989400
https://doi.org/10.1101/2020.03.12.989400