Zobrazeno 1 - 10
of 10
pro vyhledávání: '"James E. Chaney"'
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 28:373-376
A method for the rapid synthesis of [14C]-phenylethanolamine (PEOH) amenable to the preparation of [11C]-PEOH was developed under anhydrous conditions. Reaction of benzaldehyde with [14C]-NaCN in the presence of crown ethers in THF yielded [14C]-cyan
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 22:983-993
The potential of a clean, rapid exchange between the nitrile function of mandelonitrile and cyanide was examined for the preparation of labeled mandelonitrile which could be subsequently rapidly reduced with borane to labeled phenylethanolamine (PEOH
Autor:
Rensuke Goto, Masakatsu Tezuka, George A. Gigenis, Atsushi Takeda, Osamu Tamemasa, James E. Chaney
Publikováno v:
Chemical and Pharmaceutical Bulletin. 30:2521-2528
Autor:
Dennis L. Casey, A.P. Callahan, Lee C. Washburn, Raymond L. Hayes, James E. Chaney, George A. Digenis, Denise A. Wesner
Publikováno v:
The International Journal of Applied Radiation and Isotopes. 32:325-330
A rapid method for the preparation of l -phenylalanine-1-11C and d -phenylalanine-1-11C is described. dl -Phenylalanine-1-11C (375 mCi) was synthesized from 11C-cyanide (2.4 Ci) by a modified Bucherer- Strecker reaction with a chemical yield of 65% i
Publikováno v:
RADIOISOTOPES. 33:73-76
This experiment was carried out in search for stimulators of the in vivo uptake of D- and L-leucine by tumor and pancreas for the possible application to gamma-emitter labeled amino acids in nuclear medical diagnosis. Inosine, uridine, and glutamine
Publikováno v:
The International Journal of Applied Radiation and Isotopes. 32:345-348
A one solvent two-step procedure for the synthesis of [α-C]-labeled phenethylamine is described. The method employs crown ethers to aid in the solubilization of sodium cyanide in tetrahydrofuran (THF) for the formation of phenylacetonitrile from ben
Publikováno v:
Journal of pharmaceutical sciences. 71(7)
A rapid enzymatic method for the preparation of [1- 14 C]D-leucine is described. [1- 14 C]D-Leucine was obtained from [1- 14 C]DL-leucine by oxidative deamination of the L-isomer using immobilized L-amino acid oxidase. The total preparation (includin
Publikováno v:
Life sciences. 32(11)
A group of EMT6 tumor bearing male BALB/c mice which had been treated with alpha-difluoromethylornithine (DFMO, a specific, irreversible inhibitor of ornithine decarboxylase, the enzyme which catalyzes the biosynthesis of putrescine), 8 mg/mouse, ip,
Publikováno v:
Archives of biochemistry and biophysics. 126(2)
Passage of glucose and similar materials through an unstirred chloroform layer separating two aqueous compartments was greatly accelerated by addition to the chloroform of any of a variety of phospholipid fractions extracted from human erythrocyte me
Publikováno v:
Archives of biochemistry and biophysics. 126(2)
The necessity for the exclusion of water in the preparation of previously reported sugar-phospholipid complexes in highly nonpolar vehicles was found not to apply when chloroform was used as the organic solvent. The apparent chloroform/water partitio