Zobrazeno 1 - 10
of 23
pro vyhledávání: '"James E. Bupp"'
Publikováno v:
ARKIVOC, Vol 2002, Iss 10, Pp 90-96 (2003)
Externí odkaz:
https://doaj.org/article/a6a05f89e66e442c80dbb24811347b1e
Autor:
Mary J. Tanga, James E. Bupp
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 59:291-293
A stable isotope labelled mass spectrometry internal standard of the antibiotic doxycycline was prepared to assist in pharmacokinetic analyses. Our approach was to first N-demethylate doxycycline using a non-classical Polonovski reaction and then re-
Autor:
Faming Jiang, David C. Perry, James E. Bupp, Nurulain T. Zaveri, Lawrence Toll, Jinhua Wu, Willma E. Polgar
Publikováno v:
Neuropharmacology. 77:193-199
Recent genetic and pharmacological studies have implicated the α3, β4 and α5 subunits of the nicotinic acetylcholine receptor (nAChR) in dependence to nicotine and other abused drugs and nicotine withdrawal. The α3β4* nAChR subtype has been show
Autor:
James E, Bupp, Mary J, Tanga
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 59(7)
A stable isotope labelled mass spectrometry internal standard of the antibiotic doxycycline was prepared to assist in pharmacokinetic analyses. Our approach was to first N-demethylate doxycycline using a non-classical Polonovski reaction and then re-
Autor:
Karolina Pajak, Irving W. Wainer, Krzysztof Jozwiak, Mary J. Tanga, Joseph A. Kozocas, James E. Bupp, Lucita Jimenez, Anita Plazinska, Lawrence Toll
Publikováno v:
Molecular Pharmacology. 81:846-854
G protein-coupled receptors (GPCRs) are integral membrane proteins that change conformation after ligand binding so that they can transduce signals from an extracellular ligand to a variety of intracellular components. The detailed interaction of a m
Autor:
James E. Bupp, Mitesh Sanghvi, Carol E. Green, Anuradha Ramamoorthy, Kathleen O’Loughlin, Robert Swezey, Katina Sourou Sylvestre Dossou, Irving W. Wainer, Ruin Moaddel
Publikováno v:
Pharmacology Research & Perspectives
The distribution, clearance, and bioavailability of (2S,6S)-hydroxynorketamine has been studied in the Wistar rat. The plasma and brain tissue concentrations over time of (2S,6S)-hydroxynorketamine were determined after intravenous (20 mg/kg) and ora
Publikováno v:
Journal of Heterocyclic Chemistry. 40:569-573
The syntheses of the potential heterocyclic amine food mutagens l,4,6-trimethyl-2-aminoimidazo[4,5-c]-pyridine and 1,5,7-trimethyl-2-aminoimidazo[4,5-b]pyridine are described.
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 55:177-179
The α3β4 subtype of the nicotinic acetylcholine receptors (nAChR) is present in limited but specific areas of the brain unlike the widely distributed α4β2 nAChR subtype, known to be involved in the addictive effects of nicotine. Recently, the α3
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:405-411
The syntheses of the deuterium-labeled food mutagen 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine (PhIP) and its N-hydroxy metabolite are described. Unlabeled PhIP is deuterated using a boron trifluoride phosphoric acid complex in one step. Lab
Publikováno v:
Journal of Heterocyclic Chemistry. 34:717-727
The syntheses of the potential heterocyclic amine food mutagens, 3,5,7-trimethyl-2-aminoimidazo-[4,5-b]pyridine, 1,4,7-trimethyl-2-aminoimidazo[4,5-c]pyridine, 1,6,7-trimethyl-2-aminoimidazo[4,5-c]-pyridine, 3,4,6-trimethyl-2-aminoimidazo[4,5-c]pyrid