Zobrazeno 1 - 10
of 30
pro vyhledávání: '"James E. Bupp"'
Publikováno v:
ARKIVOC, Vol 2002, Iss 10, Pp 90-96 (2003)
Externí odkaz:
https://doaj.org/article/a6a05f89e66e442c80dbb24811347b1e
Autor:
Mary J. Tanga, James E. Bupp
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 59:291-293
A stable isotope labelled mass spectrometry internal standard of the antibiotic doxycycline was prepared to assist in pharmacokinetic analyses. Our approach was to first N-demethylate doxycycline using a non-classical Polonovski reaction and then re-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff7ca43b34181aaa7b304745797a9180
https://doi.org/10.1002/jlcr.3397
https://doi.org/10.1002/jlcr.3397
Autor:
Faming Jiang, David C. Perry, James E. Bupp, Nurulain T. Zaveri, Lawrence Toll, Jinhua Wu, Willma E. Polgar
Publikováno v:
Neuropharmacology. 77:193-199
Recent genetic and pharmacological studies have implicated the α3, β4 and α5 subunits of the nicotinic acetylcholine receptor (nAChR) in dependence to nicotine and other abused drugs and nicotine withdrawal. The α3β4* nAChR subtype has been show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f933e1fbbcc2be361eaa3e01901f35
https://doi.org/10.1016/j.neuropharm.2013.09.023
https://doi.org/10.1016/j.neuropharm.2013.09.023
Autor:
James E, Bupp, Mary J, Tanga
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 59(7)
A stable isotope labelled mass spectrometry internal standard of the antibiotic doxycycline was prepared to assist in pharmacokinetic analyses. Our approach was to first N-demethylate doxycycline using a non-classical Polonovski reaction and then re-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::33ddee8c0f2407c1e959e59fb585ce23
https://pubmed.ncbi.nlm.nih.gov/27061598
https://pubmed.ncbi.nlm.nih.gov/27061598
Autor:
Karolina Pajak, Irving W. Wainer, Krzysztof Jozwiak, Mary J. Tanga, Joseph A. Kozocas, James E. Bupp, Lucita Jimenez, Anita Plazinska, Lawrence Toll
Publikováno v:
Molecular Pharmacology. 81:846-854
G protein-coupled receptors (GPCRs) are integral membrane proteins that change conformation after ligand binding so that they can transduce signals from an extracellular ligand to a variety of intracellular components. The detailed interaction of a m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca23688c124b80f11faa31e764a3e899
https://doi.org/10.1124/mol.111.077347
https://doi.org/10.1124/mol.111.077347
Autor:
James E. Bupp, Mitesh Sanghvi, Carol E. Green, Anuradha Ramamoorthy, Kathleen O’Loughlin, Robert Swezey, Katina Sourou Sylvestre Dossou, Irving W. Wainer, Ruin Moaddel
Publikováno v:
Pharmacology Research & Perspectives
The distribution, clearance, and bioavailability of (2S,6S)-hydroxynorketamine has been studied in the Wistar rat. The plasma and brain tissue concentrations over time of (2S,6S)-hydroxynorketamine were determined after intravenous (20 mg/kg) and ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::065aa6a5e94d57f671284af5994704a5
http://europepmc.org/articles/PMC4492732
http://europepmc.org/articles/PMC4492732
Publikováno v:
Journal of Heterocyclic Chemistry. 40:569-573
The syntheses of the potential heterocyclic amine food mutagens l,4,6-trimethyl-2-aminoimidazo[4,5-c]-pyridine and 1,5,7-trimethyl-2-aminoimidazo[4,5-b]pyridine are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6d772974f41aa04ffcef97b908d96f9
https://doi.org/10.1002/jhet.5570400403
https://doi.org/10.1002/jhet.5570400403
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 55:177-179
The α3β4 subtype of the nicotinic acetylcholine receptors (nAChR) is present in limited but specific areas of the brain unlike the widely distributed α4β2 nAChR subtype, known to be involved in the addictive effects of nicotine. Recently, the α3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ad9d7770bb28d5565ac0579d0149311
https://doi.org/10.1002/jlcr.2923
https://doi.org/10.1002/jlcr.2923
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 44:405-411
The syntheses of the deuterium-labeled food mutagen 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine (PhIP) and its N-hydroxy metabolite are described. Unlabeled PhIP is deuterated using a boron trifluoride phosphoric acid complex in one step. Lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::248ee0a6013f6d1b6c36cfaed8ad9ce4
https://doi.org/10.1002/jlcr.468
https://doi.org/10.1002/jlcr.468
Publikováno v:
Journal of Heterocyclic Chemistry. 34:717-727
The syntheses of the potential heterocyclic amine food mutagens, 3,5,7-trimethyl-2-aminoimidazo-[4,5-b]pyridine, 1,4,7-trimethyl-2-aminoimidazo[4,5-c]pyridine, 1,6,7-trimethyl-2-aminoimidazo[4,5-c]-pyridine, 3,4,6-trimethyl-2-aminoimidazo[4,5-c]pyrid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e62705d6f18b2b7fc8eb23f5c04d33ec
https://doi.org/10.1002/jhet.5570340303
https://doi.org/10.1002/jhet.5570340303