Zobrazeno 1 - 10
of 138
pro vyhledávání: '"James E. Melvin"'
Publikováno v:
FEBS Open Bio, Vol 9, Iss 5, Pp 947-958 (2019)
Transcriptional profiling identified 933 sexually dimorphic genes out of the 14 371 protein‐coding genes expressed in the three major murine salivary glands: parotid, sublingual, and submandibular. Most (89%) sex‐specific genes were enriched in a
Externí odkaz:
https://doaj.org/article/812f01341a3a463f845cb5b45047a342
Publikováno v:
Physiological Reports, Vol 7, Iss 23, Pp n/a-n/a (2019)
Abstract Slc4a11, a member of the Slc4 HCO3− transporter family, has a wide tissue distribution. In mouse salivary glands, the expression of Slc4a11 mRNA was more than eightfold greater than the other nine members of the Slc4 gene family. The Slc4a
Externí odkaz:
https://doaj.org/article/ba837ef26de24d4d84dfc4de101a615f
Autor:
Rozita Jalali, Johannes C. Lodder, Behrouz Zandieh-Doulabi, Dimitra Micha, James E. Melvin, Marcelo A. Catalan, Huibert D. Mansvelder, Pamela DenBesten, Antonius Bronckers
Publikováno v:
Frontiers in Physiology, Vol 8 (2017)
Na+:K+:2Cl− cotransporters (NKCCs) belong to the SLC12A family of cation-coupled Cl− transporters. We investigated whether enamel-producing mouse ameloblasts express NKCCs. Transcripts for Nkcc1 were identified in the mouse dental epithelium by R
Externí odkaz:
https://doaj.org/article/4f288e92fc0943d89aea1507aef82228
Autor:
Heeseog Kang, Audrey Kerloc’h, Maxime Rotival, Xiaoqing Xu, Qing Zhang, Zelpha D’Souza, Michael Kim, Jodi Carlson Scholz, Jeong-Hun Ko, Prashant K. Srivastava, Jonathan R. Genzen, Weiguo Cui, Timothy J. Aitman, Laurence Game, James E. Melvin, Adedayo Hanidu, Janice Dimock, Jie Zheng, Donald Souza, Aruna K. Behera, Gerald Nabozny, H. Terence Cook, J.H. Duncan Bassett, Graham R. Williams, Jun Li, Agnès Vignery, Enrico Petretto, Jacques Behmoaras
Publikováno v:
Cell Reports, Vol 8, Iss 4, Pp 1210-1224 (2014)
Macrophages can fuse to form osteoclasts in bone or multinucleate giant cells (MGCs) as part of the immune response. We use a systems genetics approach in rat macrophages to unravel their genetic determinants of multinucleation and investigate their
Externí odkaz:
https://doaj.org/article/f6208b18c69045d9b837b050615cef3e
Autor:
James E. Melvin, Diptadip Dattaroy, Jürgen Wess, Mario Rossi, Jennifer Langel, Nicolai M. Doliba, Hongchao Zheng, Taro Mukaibo, Franz M. Matschinsky, Lu Zhu, Daniel H. Appella, Samer Hattar, Jonathan Pham, Amanda Cohen
Publikováno v:
Proceedings of the National Academy of Sciences. 116:18684-18690
Given the global epidemic in type 2 diabetes, novel antidiabetic drugs with increased efficacy and reduced side effects are urgently needed. Previous work has shown that M3 muscarinic acetylcholine (ACh) receptors (M3Rs) expressed by pancreatic β ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e81c3dcd8ffa6494f2ef279dc752c51
https://doi.org/10.1073/pnas.1904943116
https://doi.org/10.1073/pnas.1904943116
Publikováno v:
FEBS Open Bio
Transcriptional profiling identified 933 sexually dimorphic genes out of the 14 371 protein-coding genes expressed in the three major murine salivary glands: parotid, sublingual, and submandibular. Most (89%) sex-specific genes were enriched in a sin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::679a575ffa7eeda675bcdcd652139622
https://doi.org/10.1002/2211-5463.12625
https://doi.org/10.1002/2211-5463.12625
Publikováno v:
Journal of Cellular Physiology. 234:16376-16388
The HCO3 - secretion mechanism in salivary glands is unclear but is thought to rely on the co-ordinated activity of multiple ion transport proteins including members of the Slc4 family of bicarbonate transporters. Slc4a7 was immunolocalized to the ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb7bfda66dbd464525f3df6509b433f4
https://doi.org/10.1002/jcp.28306
https://doi.org/10.1002/jcp.28306
Publikováno v:
Journal of cellular physiologyREFERENCES. 235(11)
The widely expressed Anoctamin 6 (Ano6) supports different Ca2+ -dependent functions, but little is known about its role in salivary glands. Mouse submandibular gland (SMG) acinar cells exhibited a robust regulatory volume decrease (RVD) following ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87f786e0dc5fddd58d8445df0547ee81
https://pubmed.ncbi.nlm.nih.gov/32329061
https://pubmed.ncbi.nlm.nih.gov/32329061
Publikováno v:
Journal of Dental Research. 97:1244-1251
Mutations in the ectodysplasin A gene ( EDA) cause X-LHED (X-linked hypohidrotic ectodermal dysplasia), the most common human form of ectodermal dysplasia. Defective EDA signaling is linked to hypoplastic development of epithelial tissues, resulting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dbc7502c588b6c817831040323b2c26
https://doi.org/10.1177/0022034518782461
https://doi.org/10.1177/0022034518782461
Autor:
Marcelo A Catalán, Kathleen Scott-Anne, Marlise I Klein, Hyun Koo, William H Bowen, James E Melvin
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16549 (2011)
Dental caries is the single most prevalent and costly infectious disease worldwide, affecting more than 90% of the population in the U.S. The development of dental cavities requires the colonization of the tooth surface by acid-producing bacteria, su
Externí odkaz:
https://doaj.org/article/818c9cfb59d14025a81dde93f555ce61