Zobrazeno 1 - 10 of 431 pro vyhledávání: '"James E Klaunig"'
1
Akademický článek
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2
Akademický článek
Biotransformation of 2,4,6-tris(2,4,6-tribromophenoxy)-1,3,5-triazine (TTBP-TAZ) can contribute to high levels of 2,4,6-tribromophenol (2,4,6-TBP) in humans
Autor: Guomao Zheng, Luma Melo, Rishika Chakraborty, James E. Klaunig, Amina Salamova
Publikováno v: Environment International, Vol 158, Iss , Pp 106943- (2022)
2,4,6-Tribromophenol (2,4,6-TBP) is a brominated flame retardant that accumulates in human tissues and is a potential toxicant. Previous studies found 2,4,6-TBP levels in human tissues were significantly higher than those of brominated flame retardan
Externí odkaz: https://doaj.org/article/9395302d946749d0b93dc473cfa488dd
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3
Akademický článek
The effect of endurance training on non‐alcoholic fatty liver disease in mice
Autor: Luma Melo, Merve Bilici, Amit Hagar, James E. Klaunig
Publikováno v: Physiological Reports, Vol 9, Iss 15, Pp n/a-n/a (2021)
Abstract Chronic endurance exercise is a therapeutic strategy in the treatment of non‐alcoholic fatty liver disease (NAFLD). Metabolic, cardiorespiratory, and endocrine pathways targeted by chronic endurance exercise have been identified; however,
Externí odkaz: https://doaj.org/article/044175aa8da0420cbe61e432849b8849
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4
US regulations to curb alleged cancer causes are ineffectual and compromised by scientific, constitutional and ethical violations
Autor: Gio B. Gori, Michael Aschner, Christopher J. Borgert, Samuel M. Cohen, Daniel R. Dietrich, Corrado L. Galli, Helmut Greim, John S. Heslop-Harrison, Sam Kacew, Norbert E. Kaminski, James E. Klaunig, Hans W.J. Marquardt, Olavi Pelkonen, Ruth Roberts, Kai M. Savolainen, Aristidis Tsatsakis, Hiroshi Yamazaki
Publikováno v: Archives of Toxicology. 97:1813-1822
The 1958 Delaney amendment to the Federal Food Drug and Cosmetics Act prohibited food additives causing cancer in animals by appropriate tests. Regulators responded by adopting chronic lifetime cancer tests in rodents, soon challenged as inappropriat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f93d8c4c20fda41ae2780a1ad9e33486
https://doi.org/10.1007/s00204-022-03429-5
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7
Assessment of the mode of action underlying development of liver lesions in mice following oral exposure to HFPO-DA and relevance to humans
Autor: Melissa M Heintz, Laurie C Haws, James E Klaunig, John M Cullen, Chad M Thompson
Publikováno v: Toxicological Sciences. 192:15-29
HFPO-DA (ammonium, 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoate) is a short-chain polyfluorinated alkyl substance (PFAS) used in the manufacture of some types of fluorinated polymers. Like many PFAS, toxicity studies with HFPO-DA indicate the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f9607b33433b019341e35e8e516c2273
https://doi.org/10.1093/toxsci/kfad004
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8
Akademický článek
A computational model of liver tissue damage and repair.
Autor: Priyom Adhyapok, Xiao Fu, James P Sluka, Sherry G Clendenon, Victoria D Sluka, Zemin Wang, Kenneth Dunn, James E Klaunig, James A Glazier
Publikováno v: PLoS ONE, Vol 15, Iss 12, p e0243451 (2020)
Drug induced liver injury (DILI) and cell death can result from oxidative stress in hepatocytes. An initial pattern of centrilobular damage in the APAP model of DILI is amplified by communication from stressed cells and immune system activation. Whil
Externí odkaz: https://doaj.org/article/5bbadffbbea14e2d947bac17c18ffe2e
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