Zobrazeno 1 - 10
of 71
pro vyhledávání: '"James E Galen"'
Autor:
Scott M Baliban, Mingjun Yang, Girish Ramachandran, Brittany Curtis, Surekha Shridhar, Rachel S Laufer, Jin Y Wang, John Van Druff, Ellen E Higginson, Nicolas Hegerle, Kristen M Varney, James E Galen, Sharon M Tennant, Andrew Lees, Alexander D MacKerell, Myron M Levine, Raphael Simon
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 4, p e0005493 (2017)
Invasive infections associated with non-typhoidal Salmonella (NTS) serovars Enteritidis (SE), Typhimurium (STm) and monophasic variant 1,4,[5],12:i:- are a major health problem in infants and young children in sub-Saharan Africa, and currently, there
Externí odkaz:
https://doaj.org/article/88ec432e3410456bb21a0a20837705b1
Autor:
Raphael Simon, Jin Y Wang, Mary A Boyd, Mohan E Tulapurkar, Girish Ramachandran, Sharon M Tennant, Marcela Pasetti, James E Galen, Myron M Levine
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64680 (2013)
Non-typhoidal Salmonella (NTS) serovars S. Enteritidis and S. Typhimurium are a major cause of invasive bacterial disease (e.g., bacteremia, meningitis) in infants and young children in sub-Saharan Africa and also occasionally cause invasive disease
Externí odkaz:
https://doaj.org/article/d6b710b572b8472eab976830b96bc83a
Autor:
Orit Gat, James E Galen, Sharon Tennant, Raphael Simon, William C Blackwelder, David J Silverman, Marcela F Pasetti, Myron M Levine
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 11, p e1373 (2011)
Antibiotic-resistant Salmonella enterica serovar Paratyphi A, the agent of paratyphoid A fever, poses an emerging public health dilemma in endemic areas of Asia and among travelers, as there is no licensed vaccine. Integral to our efforts to develop
Externí odkaz:
https://doaj.org/article/7e29903c4ae5476fa2ba307b744af919
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18700 (2011)
Certain serovars of Salmonella enterica subsp. enterica cause invasive disease (e.g., enteric fever, bacteremia, septicemia, meningitis, etc.) in humans and constitute a global public health problem. A rapid, sensitive diagnostic test is needed to al
Externí odkaz:
https://doaj.org/article/4f1609f86a3e4d069f9349484aaf82bc
Autor:
Sharon M Tennant, Souleymane Diallo, Haim Levy, Sofie Livio, Samba O Sow, Milagritos Tapia, Patricia I Fields, Matthew Mikoleit, Boubou Tamboura, Karen L Kotloff, James P Nataro, James E Galen, Myron M Levine
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 4, Iss 3, p e621 (2010)
In sub-Saharan Africa, non-typhoidal Salmonella (NTS) are emerging as a prominent cause of invasive disease (bacteremia and focal infections such as meningitis) in infants and young children. Importantly, including data from Mali, three serovars, Sal
Externí odkaz:
https://doaj.org/article/1cc7e6a8fb044b468c873e7bbaf85887
Publikováno v:
Journal of applied microbiology. 131(6)
Salmonella spp. are important human pathogens globally causing millions of cases of typhoid fever and non-typhoidal salmonellosis annually. There are only a few vaccines licensed for use in humans which all target Salmonella enterica serovar Typhi. V
Autor:
James E. Galen, Hua Yu, Ashley Saint Fleur, Therwa Hamza, Kevin Chen, Yongrong Zhang, Yixuan Zhu, Hanping Feng, Zhiyong Yang
Publikováno v:
Sci Transl Med
Antibiotic-resistant Clostridioides difficile is an anaerobic Gram-positive bacterium that colonizes the colon and is responsible for more than 29,000 deaths in the United States each year. Hence, C. difficile infection (CDI) poses an urgent threat t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96ec0d534e7a6c1af8af0e04f5a02eb
https://europepmc.org/articles/PMC7692727/
https://europepmc.org/articles/PMC7692727/
Publikováno v:
Vaccines
Vaccines, Vol 9, Iss 162, p 162 (2021)
Vaccines, Vol 9, Iss 162, p 162 (2021)
The use of live-attenuated bacterial vaccines as carriers for the mucosal delivery of foreign antigens to stimulate the mucosal immune system was first proposed over three decades ago. This novel strategy aimed to induce immunity against at least two
Autor:
James E. Galen, Myron M. Levine, Rosângela Salerno-Gonçalves, Marcelo B. Sztein, Alessio Fasano
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology, Vol 9 (2018)
Although immunity induced by typhoid fever is moderated and short-lived, typhoid vaccination with the attenuated Ty21a oral vaccine generates long-lasting protection rates reaching up to 92%. Thus, there are important differences on how wild-type Sal
Autor:
James E. Galen, Marcela F. Pasetti, Myron M. Levine, Raphael Simon, Patrick J. Schmidlein, Sharon M. Tennant
Publikováno v:
Infection and Immunity. 83:4504-4512
Invasive nontyphoidal Salmonella (NTS) infections constitute a major health problem among infants and toddlers in sub-Saharan Africa; these infections also occur in infants and the elderly in developed countries. We genetically engineered a Salmonell