Zobrazeno 1 - 10
of 107
pro vyhledávání: '"James E Galagan"'
Autor:
Jared D Sharp, Atul K Singh, Sang Tae Park, Anna Lyubetskaya, Matthew W Peterson, Antonio L C Gomes, Lakshmi-Prasad Potluri, Sahadevan Raman, James E Galagan, Robert N Husson
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152145 (2016)
Expression of SigH, one of 12 Mycobacterium tuberculosis alternative sigma factors, is induced by heat, oxidative and nitric oxide stresses. SigH activation has been shown to increase expression of several genes, including genes involved in maintaini
Externí odkaz:
https://doaj.org/article/1bfa65289d2e40f5bfa25a9fe9a112fd
Autor:
Desmond S Lun, Graham Rockwell, Nicholas J Guido, Michael Baym, Jonathan A Kelner, Bonnie Berger, James E Galagan, George M Church
Publikováno v:
Molecular Systems Biology, Vol 5, Iss 1, Pp 1-8 (2009)
Abstract In the past decade, computational methods have been shown to be well suited to unraveling the complex web of metabolic reactions in biological systems. Methods based on flux–balance analysis (FBA) and bi‐level optimization have been used
Externí odkaz:
https://doaj.org/article/5d77d89976494fbaad34041058541186
Autor:
Jonathan M Dreyfuss, Jeremy D Zucker, Heather M Hood, Linda R Ocasio, Matthew S Sachs, James E Galagan
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 7, p e1003126 (2013)
The filamentous fungus Neurospora crassa played a central role in the development of twentieth-century genetics, biochemistry and molecular biology, and continues to serve as a model organism for eukaryotic biology. Here, we have reconstructed a geno
Externí odkaz:
https://doaj.org/article/f9cbcfc2850d44958456ecb969c51e43
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e80775 (2013)
Drug resistance is a common problem in the fight against infectious diseases. Recent studies have shown conditions (which we call antiR) that select against resistant strains. However, no specific drug administration strategies based on this property
Externí odkaz:
https://doaj.org/article/ce95aa88dae5414ab4e543803ba36b32
Autor:
Aaron Brandes, Desmond S Lun, Kuhn Ip, Jeremy Zucker, Caroline Colijn, Brian Weiner, James E Galagan
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36947 (2012)
Bacteria have evolved the ability to efficiently and resourcefully adapt to changing environments. A key means by which they optimize their use of available nutrients is through adjustments in gene expression with consequent changes in enzyme activit
Externí odkaz:
https://doaj.org/article/d1db28893553499f9f41ff3535f90ef0
Autor:
Caroline Colijn, Aaron Brandes, Jeremy Zucker, Desmond S Lun, Brian Weiner, Maha R Farhat, Tan-Yun Cheng, D Branch Moody, Megan Murray, James E Galagan
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 8, p e1000489 (2009)
Metabolism is central to cell physiology, and metabolic disturbances play a role in numerous disease states. Despite its importance, the ability to study metabolism at a global scale using genomic technologies is limited. In principle, complete genom
Externí odkaz:
https://doaj.org/article/2852ac27df534bb5894c94d50aae109c
Publikováno v:
PLoS ONE, Vol 3, Iss 7, p e2812 (2008)
Recent evidence suggests that the number and variety of functional RNAs (ncRNAs as well as cis-acting RNA elements within mRNAs) is much higher than previously thought; thus, the ability to computationally predict and analyze RNAs has taken on new im
Externí odkaz:
https://doaj.org/article/729304bd26d24efea58fc46899a58335
Publikováno v:
PLoS Biology, Vol 2, Iss 12, p e422 (2004)
Little is known about the patterns of intron gain and loss or the relative contributions of these two processes to gene evolution. To investigate the dynamics of intron evolution, we analyzed orthologous genes from four filamentous fungal genomes and
Externí odkaz:
https://doaj.org/article/95171a7ea9f1490ea23f75c7963f5400
Autor:
Samantha N. Muellers, Margarita A. Tararina, Uros Kuzmanovic, James E. Galagan, Karen N. Allen
Publikováno v:
Biochemistry. 62:851-862
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f857dd511fb3d512413b2abeb822220
https://doi.org/10.1021/acs.biochem.2c00540
https://doi.org/10.1021/acs.biochem.2c00540
Autor:
Marjon Zamani, Josh Dupaty, R. C. Baer, Uros Kuzmanovic, Andy Fan, Mark W. Grinstaff, James E. Galagan, Catherine M. Klapperich
Publikováno v:
ACS Omega. 7:5804-5808
Progesterone monitoring is an essential component of in vitro fertilization treatments and reproductive management of dairy cows. Gold-standard biosensors for progesterone monitoring rely on antibodies, which are expensive and difficult to procure. W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f49ca6b1dba386b319552c5e27ee693a
https://doi.org/10.1021/acsomega.1c05737
https://doi.org/10.1021/acsomega.1c05737