Výsledky vyhledávání - "James E Boers"

Akademický článek

Fully automated fluorescent in situ hybridization (FISH) staining and digital analysis of HER2 in breast cancer: a validation study.

Autor: Elise M J van der Logt, Deborah A J Kuperus, Jan W van Setten, Marius C van den Heuvel, James E Boers, Ed Schuuring, Robby E Kibbelaar

Publikováno v: PLoS ONE, Vol 10, Iss 4, p e0123201 (2015)

HER2 assessment is routinely used to select patients with invasive breast cancer that might benefit from HER2-targeted therapy. The aim of this study was to validate a fully automated in situ hybridization (ISH) procedure that combines the automated

Externí odkaz: https://doaj.org/article/6857031acd694cfcae604ea7e3c30179

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Use of trastuzumab for HER2-positive metastatic breast cancer in daily practice

Autor: Linda de Munck, Jacques C. de Graaf, Frank G A Jansman, Sabine Siesling, James E. Boers, Johan M. van Rooijen, Guusje M. Teeuwen

Publikováno v: Anti-cancer drugs, 27(2), 127-132. Lippincott Williams and Wilkins
Anti-Cancer Drugs, 27(2), 127-32. LIPPINCOTT WILLIAMS & WILKINS

The addition of trastuzumab to chemotherapy in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer (MBC) prolongs overall survival (OS) in clinical trials. However, treatment patterns and survival in daily practice are u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df098d0a3f70085ef62cab4964d8f34b
https://research.rug.nl/en/publications/e6dfbbe2-5cd3-4c45-88fc-6243cc071274

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Androgen receptor expression inversely correlates with immune cell infiltration in human epidermal growth factor receptor 2-positive breast cancer

Autor: Elisabeth G.E. de Vries, Johan M. van Rooijen, Si-Qi Qiu, James E. Boers, Bert van der Vegt, Hetty Timmer-Bosscha, Carolien P. Schröder

Publikováno v: European Journal of Cancer, 103, 52-60. ELSEVIER SCI LTD

Introduction: Although targeting human epidermal growth factor receptor 2 (HER2) is a meaningful treatment in HER2-positive breast cancer, ultimately resistance develops. Androgen receptor (AR) expression and immune cell infiltration are thought to b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::486ff56c2d2dc84a9d85cdc1f50ddf06
https://pubmed.ncbi.nlm.nih.gov/30208359

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Dose-escalation study of G1T48, an oral selective estrogen receptor degrader (SERD), in postmenopausal women with ER+/HER2- locally advanced or metastatic breast cancer (ABC)

Autor: E.G.E. de Vries, Jie Xiao, Chao Li, Elizabeth Claire Dees, Houven van Oordt, C.W. Menke-van der, Philippe Aftimos, Andrew P. Beelen, Patrick Neven, Christina Sipes, Mark D. Pegram, Rajesh K. Malik, James E. Boers, Jessica A. Sorrentino, Ramsha Iqbal

Publikováno v: Annals of Oncology. 30:v121-v122

Background The SERD fulvestrant is a well-established therapy for ER+/HER2- ABC. However, its intramuscular route of administration may be painful and limits systemic exposure. G1T48 is a highly potent and efficacious oral SERD in both mutant and WT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9bef848842f422861d4fe1e8f52ba1e
https://doi.org/10.1093/annonc/mdz242.035

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Trastuzumab and bevacizumab combined with docetaxel, oxaliplatin and capecitabine as first-line treatment of advanced HER2-positive gastric cancer: a multicenter phase II study

Autor: Jan H.M. Schellens, Maartje Los, Margot E T Tesselaar, Didier Meulendijks, S. H. Goey, Maria Kuiper, Jan Willem B. de Groot, Laurens V. Beerepoot, Johanna E.A. Portielje, Steven A L W Vanhoutvin, Aart Beeker, Robert S. de Jong, James E. Boers, Annemieke Cats, Jos H. Beijnen, Henk Boot, Marco B. Polee, Karolina Sikorska

Publikováno v: Investigational New Drugs, 34(1), 119. Kluwer Academic Publishers

Summary: Objective To investigate the efficacy of bevacizumab and trastuzumab combined with docetaxel, oxaliplatin, and capecitabine (B-DOCT) as first-line treatment of advanced human epidermal growth factor receptor 2 (HER2)-positive gastric cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e16010755f68b8fe75ce502f1830437
https://dspace.library.uu.nl/handle/1874/330130

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Percutaneous Ultrasound-Guided Biopsies in the Evaluation of Thoracic Tumours after PET-CT

Autor: Jos A. Stigt, Ad H. Oostdijk, James E. Boers, Jan Willem K. van den Berg, Harry J.M. Groen

Publikováno v: Respiration, 83(1), 45-52. KARGER

Background: Lesions detected by positron emission tomography-computed tomography (PET-CT) during the analysis of thoracic tumours are often impalpable at physical examination, and subsequent ultrasound (US) may aid in finding these lesions for pathol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49979920d53b9ba4b4328e51ad97ab1b
https://doi.org/10.1159/000330018

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Mediastinal Incidentalomas

Autor: Harry J.M. Groen, Jos A. Stigt, Jan-Willem K. van den Berg, James E. Boers, Ad H. Oostdijk

Publikováno v: Journal of Thoracic Oncology, 6(8), 1345-1349. ELSEVIER SCIENCE INC

Introduction: Incidental mediastinal lymphadenopathy challenges pulmonologists to decide on eventual further diagnostic steps. The aim of this study was to characterize unexpected mediastinal findings by imaging and pathologic analysis.Methods: Entry

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ca2648cb17e788f25d6c6434d743f2b
https://research.rug.nl/en/publications/9b8eb726-17b9-438f-911e-4779336437d1

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HER2 status in gastro-oesophageal adenocarcinomas assessed by two rabbit monoclonal antibodies (SP3 and 4B5) and two in situ hybridization methods (FISH and SISH)

Autor: Harriëtte Meeuwissen, James E. Boers, Natalie Methorst

Publikováno v: Histopathology. 58:383-394

Aims HER2 gene amplification has been detected in 10–20% of gastric adenocarcinomas. In view of the recently demonstrated clinical benefit of the anti-human epidermal growth factor receptor 2 (HER2) drug trastuzumab in the treatment of advanced gas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32d05bc6585cf292fcb1d99bc2861633
https://doi.org/10.1111/j.1365-2559.2011.03760.x

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Pathologic examination of sentinel lymph nodes in breast cancer by a single haematoxylin-eosin slide versus serial sectioning and immunocytokeratin staining: clinical implications

Autor: Reinou S. Groen, A. Wolter J. Oosterhuis, James E. Boers

Publikováno v: Breast Cancer Research and Treatment

The objective was to determine the additional value of pathologic examination using three-level sectioning and immunocytokeratin (ICK) staining of sentinel lymph node (SN) biopsies in cT1-2N0M0 breast carcinoma patients regarding lymph node staging a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e7e4ceb745aadc7b74e60b45d44f25a
https://doi.org/10.1007/s10549-006-9434-2

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Ultrasound-Guided Tissue Core Biopsies in Supraclavicular Lymph Nodes in Patients with Suspected Thoracic Malignancies

Autor: James E. Boers, Jos A. Stigt, Martijn F. Boomsma

Publikováno v: Respiration; international review of thoracic diseases. 90(5)

Background: Supraclavicular (SC) lymph node metastases are important in the analysis of thoracic malignancies for staging as well as for diagnosing purposes. Ultrasound (US) guidance visualises lesions very precisely, enabling tissue biopsies in real

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd112c69c0296cbf4bc652acdb6f45b7
https://pubmed.ncbi.nlm.nih.gov/26484528

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