Zobrazeno 1 - 10
of 37
pro vyhledávání: '"James E, Moon"'
Autor:
Jay W. Hooper, Steven A. Kwilas, Matthew Josleyn, Sarah Norris, Jack N. Hutter, Melinda Hamer, Jeffrey Livezey, Kristopher Paolino, Patrick Twomey, Michael Koren, Paul Keiser, James E. Moon, Ugo Nwaeze, Jason Koontz, Carmen Ledesma-Feliciano, Nathalie Landry, Trevor Wellington
Publikováno v:
npj Vaccines, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Hantaan virus (HTNV) and Puumala virus (PUUV) are pathogenic zoonoses found in Asia and Europe, respectively. We conducted a randomized Phase 1 clinical trial of individual HTNV and PUUV DNA vaccines targeting the envelope glycoproteins (GnG
Externí odkaz:
https://doaj.org/article/09a21f68e1904d48a992bd029941bd0e
Autor:
Jeffrey Livezey, Patrick Twomey, Meshell Morrison, Susan Cicatelli, Elizabeth H. Duncan, Melinda Hamer, Christine Lee, Jack Hutter, Kristin Mills, Jesse DeLuca, Lucas Poon, Daniel Selig, Chau Vuong, Jason Sousa, Thomas Oliver, Jason Bennett, James E. Moon, April Sikaffy, Martha Sedegah, Donna Tosh, Mara Kreishman-Deitrick, Paige Waterman
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Abstract Background Malaria remains the top infectious disease threat facing the U.S. military in many forward operating environments. Compliance with malaria chemoprophylaxis remains a critical component in preventing malaria in the deployed Service
Externí odkaz:
https://doaj.org/article/ed1d3d6b98974024a5273f7695a18fba
Autor:
Geneviève M. Labbé, Kazutoyo Miura, Sarah E. Silk, Wenjuan Gu, James E. Moon, Jing Jin, Ruth O. Payne, Michael P. Fay, Sheetij Dutta, Carole A. Long, Simon J. Draper
Publikováno v:
Malaria Journal, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract Background The ability to report vaccine-induced IgG responses in terms of µg/mL, as opposed arbitrary units (AU), enables a more informed interpretation of the magnitude of the immune response, and better comparison between vaccines target
Externí odkaz:
https://doaj.org/article/616891eb1b9a42dcaad67533514c0010
Autor:
Kristopher M, Paolino, Jason A, Regules, James E, Moon, Richard C, Ruck, Jason W, Bennett, Shon A, Remich, Kristin T, Mills, Leyi, Lin, Cadeidre N, Washington, Ghariwayne A, Fornillos, Changhong Y, Lindsey, Kristan A, O'Brien, Meng, Shi, R, Mark Jones, Brian J, Green, Stephen, Tottey, Jessica A, Chichester, Stephen J, Streatfield, Vidadi, Yusibov
Publikováno v:
Vaccine. 40:1864-1871
The potential use of Bacillus anthracis as a bioterrorism weapon requires a safe and effective vaccine that can be immediately distributed for mass vaccination. Protective antigen (PA), a principal component of virulence factors edema toxin and letha
Autor:
Jeffrey M, Osgood, Jeffrey W, Froude, Sherri P, Daye, Oscar A, Cabrera, Matthew R, Scherer, Vincent F, Capaldi, Nelson L, Michael, James E, Moon, Eric D, Lombardini, Sheila A, Peel, Karen P, Peterson, Deydre S, Teyhen, Clinton K, Murray, Robert J, O'Connell
Publikováno v:
Military Medicine
Introduction At the start of the coronavirus disease 2019 (COVID-19) pandemic, Walter Reed Army Institute of Research (WRAIR) mobilized to rapidly conduct medical research to detect, prevent, and treat the disease in order to minimize the impact of t
Autor:
Jack N Hutter, Paul M. Robben, Christine Lee, Melinda Hamer, James E. Moon, Kristen Merino, Lei Zhu, Heather Galli, Xiaofei Quinn, Dallas R. Brown, Elizabeth Duncan, Jessica Bolton, Xiaoyan Zou, Evelina Angov, David E. Lanar, Mangala Rao, Gary R. Matyas, Zoltan Beck, Elke Bergmann-Leitner, Lorraine A. Soisson, Norman C. Waters, Viseth Ngauy, Jason Regules, Sheetij Dutta
Publikováno v:
Vaccine. 40(40)
The global burden of malaria remains substantial. Circumsporozoite protein (CSP) has been demonstrated to be an effective target antigen, however, improvements that offer more efficacious and more durable protection are still needed. In support of re
Autor:
Jack N Hutter, Jason C. Sousa, Elizabeth H. Duncan, Kristin Mills, Daniel J. Selig, Donna Tosh, Paige E. Waterman, Jesse P. DeLuca, Lucas Poon, Patrick S. Twomey, Susan Cicatelli, Jason W. Bennett, Melinda Hamer, Meshell Morrison, Christine Lee, James E. Moon, Jeffrey R. Livezey, Martha Sedegah, Thomas Oliver, April K Sikaffy, Mara Kreishman-Deitrick, Chau Vuong
Publikováno v:
Malaria Journal, Vol 19, Iss 1, Pp 1-14 (2020)
Malaria Journal
Malaria Journal
Background Malaria remains the top infectious disease threat facing the U.S. military in many forward operating environments. Compliance with malaria chemoprophylaxis remains a critical component in preventing malaria in the deployed Service Member.
Autor:
James E, Moon, Christian, Ockenhouse, Jason A, Regules, Johan, Vekemans, Cynthia, Lee, Ilin, Chuang, Magali, Traskine, Erik, Jongert, Karen, Ivinson, Danielle, Morelle, Jack L, Komisar, Marc, Lievens, Martha, Sedegah, Lindsey S, Garver, April K, Sikaffy, Norman C, Waters, William Ripley, Ballou, Opokua, Ofori-Anyinam, Linda, Murray
Publikováno v:
The Journal of Infectious Diseases
Background A previous RTS,S/AS01B vaccine challenge trial demonstrated that a 3-dose (0-1-7–month) regimen with a fractional third dose can produce high vaccine efficacy (VE) in adults challenged 3 weeks after vaccination. This study explored the V
Autor:
William F. McCarthy, Donna Tosh, Kristopher M Paolino, Meshell N Morrison, James E Moon, Sean R Marcsisin, Jason W. Bennett, Christian A Darko, Qigui Li, Patrick Twomey, Philip L Smith, Brittney M Potter, Gregory A Reichard, Susan B Cicatelli, Brandon S Pybus, Kristin T Mills, Jeffrey W Froude, Thomas G Oliver, Michele D. Spring, Norman C. Waters, Jason C Sousa
Publikováno v:
The Journal of Infectious Diseases
BackgroundPlasmodium vivax malaria requires a 2-week course of primaquine (PQ) for radical cure. Evidence suggests that the hepatic isoenzyme cytochrome P450 2D6 (CYP2D6) is the key enzyme required to convert PQ into its active metabolite.MethodsCYP2
Autor:
James E, Moon, Melissa E, Greenleaf, Jason A, Regules, Muriel, Debois, Elizabeth H, Duncan, Martha, Sedegah, Ilin, Chuang, Cynthia K, Lee, April K, Sikaffy, Lindsey S, Garver, Karen, Ivinson, Evelina, Angov, Danielle, Morelle, Marc, Lievens, Christian F, Ockenhouse, Viseth, Ngauy, Opokua, Ofori-Anyinam
Publikováno v:
Vaccine. 39(43)
We previously demonstrated that RTS,S/AS0149 participants (P-Fx: 25; NP-Fx: 24) received a fractional (1/5th dose-volume) RTS,S/AS01Overall vaccine efficacy against re-challenge was 53% (95% CI: 37-65%), and similar for P-Fx (52% [95% CI: 28-68%]) an