Zobrazeno 1 - 10
of 15
pro vyhledávání: '"James E, Estep"'
Autor:
James W. Le Duc, Kevin Anderson, Marshall E. Bloom, James E. Estep, Heinz Feldmann, Joan B. Geisbert, Thomas W. Geisbert, Lisa Hensley, Michael Holbrook, Peter B. Jahrling, Thomas G. Ksiazek, George Korch, Jean Patterson, John P. Skvorak, Hana Weingartl
Publikováno v:
Emerging Infectious Diseases, Vol 14, Iss 11, Pp 1685-1688 (2008)
Construction of several new Biosafety Level 4 (BSL-4) laboratories and expansion of existing operations have created an increased international demand for well-trained staff and facility leaders. Directors of most North American BSL-4 laboratories me
Externí odkaz:
https://doaj.org/article/831434f67ce446cabb48bb63ca9ebe45
Autor:
Conrad P, Quinn, Carol L, Sabourin, Nancy A, Niemuth, Han, Li, Vera A, Semenova, Thomas L, Rudge, Heather J, Mayfield, Jarad, Schiffer, Robert S, Mittler, Chris C, Ibegbu, Jens, Wrammert, Rafi, Ahmed, April M, Brys, Robert E, Hunt, Denyse, Levesque, James E, Estep, Roy E, Barnewall, David M, Robinson, Brian D, Plikaytis, Nina, Marano, L E, Mathes
Publikováno v:
Clinical and Vaccine Immunology. 19:1730-1745
A 3-dose (0, 1, and 6 months) intramuscular (3-IM) priming series of a human dose (HuAVA) and dilutions of up to 1:10 of anthrax vaccine adsorbed (AVA) provided statistically significant levels of protection (60 to 100%) against inhalation anthrax fo
Autor:
Karyol Poole, Sheryl Ruppel, Matthias Gromeier, Sarah K. Lawson, Christian Goetz, James O. Peggins, Robert W. Walters, Karen W. Muszynski, Elena Y. Dobrikova, James E. Estep, Steven L. Giardina, Eric M. Vela
Publikováno v:
Journal of Virology. 86:2750-2759
A dependence of poliovirus on an unorthodox translation initiation mode can be targeted selectively to drive viral protein synthesis and cytotoxicity in malignant cells. Transformed cells are naturally susceptible to poliovirus, due to widespread ect
Autor:
Brock M. Miniard, James O. Peggins, Raymond D. Harris, Ronald D. Alvarez, Thomas L. Rudge, Akseli Hemminki, Meredith A. Preuss, Minghui Wang, David T. Curiel, Rosemarie Aurigemma, Trevor Broadt, Michael J. Ryan, Gene P. Siegal, Kenneth H. Kim, James E. Estep
Publikováno v:
Human Gene Therapy. 22:821-828
Conditionally replicative adenoviral (CRAd) virotherapy represents a promising therapeutic approach for cancer. We have demonstrated that a serotype chimeric adenoviral 5/3 fiber-knob modification achieves enhanced ovarian cancer infectivity, conditi
Autor:
Norman L. Letvin, Robert E. Hunt, Yun Shen, William R. Jacobs, Dan Huang, Crystal Y. Chen, George Du, Barton F. Haynes, James E. Estep, Richard Wang, Zheng W. Chen, Ling Shen, Liyou Qiu
Publikováno v:
The Journal of Infectious Diseases. 198:1514-1519
The immune mechanisms by which early host-mycobacterium interaction leads to the development of severe tuberculosis (TB) remain poorly characterized in humans. Here, we demonstrate that severe TB in juvenile rhesus monkeys down-regulated many genes i
Autor:
Marshall E. Bloom, Thomas W. Geisbert, Heinz Feldmann, Joan B. Geisbert, George W. Korch, James E. Estep, Jean L. Patterson, John P. Skvorak, Michael R. Holbrook, Peter B. Jahrling, Hana M. Weingartl, Kevin Anderson, Lisa E. Hensley, Thomas G. Ksiazek, James W. Le Duc
Publikováno v:
Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 14, Iss 11, Pp 1685-1688 (2008)
Emerging Infectious Diseases, Vol 14, Iss 11, Pp 1685-1688 (2008)
One-sentence summary for table of contents: Training should include theoretical consideration of biocontainment principles, practical hands-on training, and mentored on-the-job experience.
Construction of several new Biosafety Level 4 (BSL-4) la
Construction of several new Biosafety Level 4 (BSL-4) la
Autor:
Michael C. Babin, Carl Nielsen, Robert Carnes, Robert E. Hunt, Daphne Vasconcelos, John Carney, James E. Estep, Roy E. Barnewall
Publikováno v:
Laboratory Investigation. 83:1201-1209
Anthrax is considered a serious biowarfare and bioterrorism threat because of its high lethality, especially by the inhalation route. Rhesus macaques (Macaca mulatta) are the most commonly used nonhuman primate model of human inhalation anthrax expos
Autor:
Catherine L. Wilhelmsen, Gene O. Nelson, James E. Estep, Sina Bavari, Ross D. LeClaire, Robert E. Hunt
Publikováno v:
Toxicologic Pathology. 24:619-626
Nonhuman primates are the established model for evaluating toxic responses to staphylococcal enterotoxins (SEs), as they react similarly to humans. Rodents are generally considered unresponsive to SEs. Binding affinities and T-cell reactivity suggest
Publikováno v:
Military Medicine. 158:587-590
Environmental contamination is a public health issue. Fish or other aquatic animal kills can be a sign that contamination of the aquatic environment has occurred. They are highly visible to the public. When such kills occur in water bodies on militar
Autor:
James E. Estep, Carol L. K. Sabourin, Stacy L. Casbohm, Kimberly S Rowell, Patrick J. Sabourin, Jennifer A. Price, Richard Scott Tuttle, James V. Rogers, Mark R. Perry
Publikováno v:
Journal of immunotoxicology. 3(1)
There is evidence for immunotoxicity of aflatoxin B1 (AFB(1)) in chronic animal feeding studies; however, little information is available as to the effects of inhalation exposure. This study evaluated the acute affects of aerosolized AFB(1) on system