Zobrazeno 1 - 10
of 32
pro vyhledávání: '"James Dylewski"'
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284636 (2023)
Podocytes are key to preventing the filtration of serum proteins into the urine. Recent evidence also suggests that in immune mediated kidney diseases, podocytes are the targets of immune complexes (ICs). The mechanisms whereby podocytes handle and r
Externí odkaz:
https://doaj.org/article/ee5b98f73cb748ce8d589d960a63d6c9
Publikováno v:
Kidney Medicine, Vol 1, Iss 4, Pp 217-220 (2019)
Guidelines recommend that patients treated with continuous renal replacement therapy be delivered an effluent dose of 20 to 25 mL/kg/h. There is debate, especially at the extremes of body mass index, as to whether actual or ideal body weight (IBW) sh
Externí odkaz:
https://doaj.org/article/9c5b88d3bd4940c697edda83004eb401
Autor:
James Dylewski, Evgenia Dobrinskikh, Linda Lewis, Pantipa Tonsawan, Makoto Miyazaki, Parmjit S Jat, Judith Blaine
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0209732 (2019)
Proteinuria is strongly associated with kidney disease progression but the mechanisms underlying podocyte handling of serum proteins such as albumin and IgG remain to be elucidated. We have previously shown that albumin and IgG are transcytosed by po
Externí odkaz:
https://doaj.org/article/6429773ab2654fc4a6ad7bd6706fe950
Autor:
Judith Blaine, James Dylewski
Publikováno v:
Cells, Vol 9, Iss 7, p 1700 (2020)
Podocytes are an integral part of the glomerular filtration barrier, a structure that prevents filtration of large proteins and macromolecules into the urine. Podocyte function is dependent on actin cytoskeleton regulation within the foot processes,
Externí odkaz:
https://doaj.org/article/cdf28c9877ac4ade9e21eae39b0352f9
Podocytes are key to preventing the filtration of serum proteins into the urine. Recent evidence also suggests that in immune mediated kidney diseases, podocytes are the targets of immune complexes (ICs). The mechanisms whereby podocytes handle and r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c02d42b582d0640351f1b0f23446ac09
https://doi.org/10.21203/rs.3.rs-2011460/v1
https://doi.org/10.21203/rs.3.rs-2011460/v1
Publikováno v:
Kidney Medicine
Kidney Medicine, Vol 1, Iss 4, Pp 217-220 (2019)
Kidney Medicine, Vol 1, Iss 4, Pp 217-220 (2019)
Guidelines recommend that patients treated with continuous renal replacement therapy be delivered an effluent dose of 20 to 25 mL/kg/h. There is debate, especially at the extremes of body mass index, as to whether actual or ideal body weight (IBW) sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4395d77c4e5ec9e55177bbe58c5e46c
https://doi.org/10.1016/j.xkme.2019.04.007
https://doi.org/10.1016/j.xkme.2019.04.007
Autor:
James Dylewski, Judith Blaine
Publikováno v:
Cells, Vol 9, Iss 1700, p 1700 (2020)
Cells
Cells
Podocytes are an integral part of the glomerular filtration barrier, a structure that prevents filtration of large proteins and macromolecules into the urine. Podocyte function is dependent on actin cytoskeleton regulation within the foot processes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aec136605570230281e00255f8a7fca
https://www.mdpi.com/2073-4409/9/7/1700
https://www.mdpi.com/2073-4409/9/7/1700
Podocytes have been proposed to be antigen presenting cells (APCs). In traditional APCs, the neonatal Fc receptor (FcRn) is required for antigen presentation and global knockout of FcRn protects against immune-mediated kidney disease. Since podocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419f7588f2b2e2bfd0b35e975193b573
Autor:
James Dylewski, Stuart L. Linas
Publikováno v:
Mayo Clinic Proceedings. 93:551-554
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1edf7ced96c221a2ab3c72475602d043
https://doi.org/10.1016/j.mayocp.2018.03.019
https://doi.org/10.1016/j.mayocp.2018.03.019
Publikováno v:
Am J Physiol Cell Physiol
The neonatal Fc receptor (FcRn) has been shown to be required for antigen presentation in dendritic cells, and global knockout of FcRn attenuates immune-mediated kidney disease. Podocytes express interleukin-6 (IL-6) receptor and produce IL-6 under p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52df60ba6bd9a67e9f701201b52b234c
https://pubmed.ncbi.nlm.nih.gov/31553647
https://pubmed.ncbi.nlm.nih.gov/31553647