Zobrazeno 1 - 10
of 2 168
pro vyhledávání: '"James Douglas"'
Autor:
Daishi Ishihara, Atsushi Hasegawa, Ikuo Hirano, James Douglas Engel, Masayuki Yamamoto, Ritsuko Shimizu
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-5 (2024)
Abstract Transcription factor GATA1 controls the delicate balance between proliferation, differentiation and apoptosis in both the erythroid and megakaryocytic lineages. In addition to full-length GATA1, there is an GATA1 isoform, GATA1s, that lacks
Externí odkaz:
https://doaj.org/article/0da7065f10014576957b099afcbee69c
Publikováno v:
Experimental Hematology & Oncology, Vol 13, Iss 1, Pp 1-5 (2024)
Abstract GATA1 plays a critical role in differentiation, proliferation, and apoptosis during erythropoiesis. We developed a Gata1 knock-down allele (Gata1.05) that results in GATA1 expression at 5% of endogenous level. In female mice heterozygous for
Externí odkaz:
https://doaj.org/article/8a38ad00d0c8452391411aa2d69f0211
Autor:
Hui Zhao, Harshil Patel, James Douglas Thornton, Eric Schaefer, Chan Shen, Douglas Leslie, Tyler Varisco, Mina Shrestha, Matthew Wanat, Randa Al Saadi
Publikováno v:
BMJ Open, Vol 14, Iss 5 (2024)
Objective To evaluate co-prescribing of sedatives hypnotics and opioids.Design Retrospective study evaluating the association of patient characteristics and comorbidities with coprescribing.Setting and participants Using the national Merative MarketS
Externí odkaz:
https://doaj.org/article/b5b95a6ecda34c35aedf5f635831186b
Autor:
Bingrui Wang, Chenchen Wang, Yang Wan, Jie Gao, Yige Ma, Yingnan Zhang, Jingyuan Tong, Yingchi Zhang, Jinhua Liu, Lixian Chang, Changlu Xu, Biao Shen, Yumei Chen, Erlie Jiang, Ryo Kurita, Yukio Nakamura, Kim-Chew Lim, James Douglas Engel, Jiaxi Zhou, Tao Cheng, Xiaofan Zhu, Ping Zhu, Lihong Shi
Publikováno v:
Cell Discovery, Vol 8, Iss 1, Pp 1-19 (2022)
Abstract Ribosomal protein dysfunction causes diverse human diseases, including Diamond–Blackfan anemia (DBA). Despite the universal need for ribosomes in all cell types, the mechanisms underlying ribosomopathies, which are characterized by tissue-
Externí odkaz:
https://doaj.org/article/9b5ff8adcf4941ae8efd9d63a2f23084
Autor:
Khiyam Hussain, Rena Liu, Rosanna C. G. Smith, Kri T. J. Müller, Mohammadmersad Ghorbani, Sofia Macari, Kirstie L. S. Cleary, Robert J. Oldham, Russell B. Foxall, Sonya James, Steven G. Booth, Tom Murray, Lekh N. Dahal, Chantal E. Hargreaves, Robert S. Kemp, Jemma Longley, James Douglas, Hannah Markham, Serena J. Chee, Richard J. Stopforth, Ali Roghanian, Matthew J. Carter, Christian H. Ottensmeier, Bjorn Frendéus, Ramsey I. Cutress, Ruth R. French, Martin J. Glennie, Jonathan C. Strefford, Stephen M. Thirdborough, Stephen A. Beers, Mark S. Cragg
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-32 (2022)
Abstract Background Hypoxia is a hallmark of the tumor microenvironment (TME) and in addition to altering metabolism in cancer cells, it transforms tumor-associated stromal cells. Within the tumor stromal cell compartment, tumor-associated macrophage
Externí odkaz:
https://doaj.org/article/4a2581bb496d4f649850cb54190883b9
Autor:
James Douglas Sinnatwah, Hajah Kenneh, Alvan A. Coker, Wahdae-Mai Harmon-Gray, Joelyn Zankah, Liam Day, Emma Hubbell, Michael J. Murphy, Mandy Izzo, David Kong, Peter Sylwester, Qinghua Long, Elena Bertozzi, Laura A. Skrip
Publikováno v:
Frontiers in Digital Health, Vol 3 (2022)
Innovative game-based training methods that leverage the ubiquity of cellphones and familiarity with phone-based interfaces have the potential to transform the training of public health practitioners in low-income countries such as Liberia. This arti
Externí odkaz:
https://doaj.org/article/3b4953d926a240be9ee053c597278a08
Autor:
Lingfei Weng, Lan Xue, Jeffrey Sayer, Rebecca Anne Riggs, James Douglas Langston, Agni Klintuni Boedhihartono
Publikováno v:
Research in Globalization, Vol 3, Iss , Pp 100074- (2021)
In 2013, China launched its ‘Belt and Road Initiative’ (BRI) as a major effort to enhance international trade and economic development. An important feature of the BRI is that it supports free trade regimes and a world economy based upon open reg
Externí odkaz:
https://doaj.org/article/88af58095b6e4dfdbd8fecc36dbc16a7
Publikováno v:
iScience, Vol 24, Iss 8, Pp 102836- (2021)
Summary: Infectious diseases continually pose global medical challenges. The transcription factor GATA2 establishes gene networks and defines cellular identity in hematopoietic stem/progenitor cells and in progeny committed to specific lineages. GATA
Externí odkaz:
https://doaj.org/article/64bce0cd1d1c4937959e05f11315140f
Autor:
Joep J. de Jong, Yang Liu, A. Gordon Robertson, Roland Seiler, Clarice S. Groeneveld, Michiel S. van der Heijden, Jonathan L. Wright, James Douglas, Marc Dall’Era, Simon J. Crabb, Bas W. G. van Rhijn, Kim E. M. van Kessel, Elai Davicioni, Mauro A. A. Castro, Yair Lotan, Ellen C. Zwarthoff, Peter C. Black, Joost L. Boormans, Ewan A. Gibb
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-13 (2019)
Abstract Background Muscle-invasive bladder cancer (MIBC) is a heterogeneous disease, and gene expression profiling has identified several molecular subtypes with distinct biological and clinicopathological characteristics. While MIBC subtyping has p
Externí odkaz:
https://doaj.org/article/f48f6e80fa2e412ea8f4dae7124976e4
Autor:
Kalifi Ferretti-Gallon, James Douglas Langston, Guangyu Wang, Kebiao Huang, Chao Long, Hongbo Zhai
Publikováno v:
Climate, Vol 10, Iss 4, p 52 (2022)
Forest restoration is increasingly becoming a priority at international and national levels. Identifying forest degradation, however, is challenging because its drivers are underlying and site-specific. Existing frameworks and principles for identify
Externí odkaz:
https://doaj.org/article/940e3ef354ce403092d9659287a70605