Zobrazeno 1 - 10
of 21
pro vyhledávání: '"James Doecke"'
Autor:
Belinda M. Brown, Natalie Frost, Stephanie R. Rainey-Smith, James Doecke, Shaun Markovic, Nicole Gordon, Michael Weinborn, Hamid R. Sohrabi, Simon M. Laws, Ralph N. Martins, Kirk I. Erickson, Jeremiah J. Peiffer
Publikováno v:
Alzheimer’s Research & Therapy, Vol 13, Iss 1, Pp 1-9 (2021)
Abstract Background Physical inactivity has been consistently linked to increased risk of cognitive decline; however, studies examining the impact of exercise interventions on cognition have produced inconsistent findings. Some observational studies
Externí odkaz:
https://doaj.org/article/cb91ebb067e34a4fbb38f82334ec269d
Autor:
Pierrick Bourgeat, Vincent Doré, James Doecke, David Ames, Colin L. Masters, Christopher C. Rowe, Jurgen Fripp, Victor L. Villemagne
Publikováno v:
NeuroImage, Vol 226, Iss , Pp 117593- (2021)
Background: : Centiloid was introduced to harmonise β-Amyloid (Aβ) PET quantification across different tracers, scanners and analysis techniques. Unfortunately, Centiloid still suffers from some quantification disparities in longitudinal analysis w
Externí odkaz:
https://doaj.org/article/f8adb122c9534af4aa3868725cd5b06f
Autor:
Steve Pedrini, Veer B. Gupta, Eugene Hone, James Doecke, Sid O’Bryant, Ian James, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Ralph N. Martins, AIBL Research Group
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Alzheimer’s Disease (AD) is the most common form of dementia, characterised by extracellular amyloid deposition as plaques and intracellular neurofibrillary tangles of tau protein. As no current clinical test can diagnose individuals at ri
Externí odkaz:
https://doaj.org/article/28c8e933dd1349c98d3838986758d187
Autor:
Noelia Fandos, Virginia Pérez‐Grijalba, Pedro Pesini, Salvador Olmos, Matías Bossa, Victor L. Villemagne, James Doecke, Christopher Fowler, Colin L. Masters, Manuel Sarasa, AIBL Research Group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 8, Iss 1, Pp 179-187 (2017)
Abstract Introduction Plasma amyloid β (Aβ) peptides have been previously studied as candidate biomarkers to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. Methods Free and total Aβ42/40 plasma rat
Externí odkaz:
https://doaj.org/article/688464d11df04c72be99820729a02c57
Autor:
Veer Bala Gupta, Eugene Hone, Steve Pedrini, James Doecke, Sid O'Bryant, Ian James, Ashley I. Bush, Christopher C. Rowe, Victor L. Villemagne, David Ames, Colin L. Masters, Ralph N. Martins, AIBL Research Group
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 8, Iss 1, Pp 60-72 (2017)
Abstract Introduction A blood‐based biomarker panel to identify individuals with preclinical Alzheimer's disease (AD) would be an inexpensive and accessible first step for routine testing. Methods We analyzed 14 biomarkers that have previously been
Externí odkaz:
https://doaj.org/article/1cf50677cf094fa6951f581aebda5f28
Autor:
Desmond Patrick, James Doecke, James Irwin, Katherine Hanigan, Lisa Simms, Mariko Howlett, Graham Radford-Smith
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 11 (2018)
Background: Patients on immunosuppression at the time of acute severe ulcerative colitis have been suggested to be at a higher risk of colectomy than those who are treatment-naïve. The aim of this study was to examine the effect of immunosuppressive
Externí odkaz:
https://doaj.org/article/d487053ef7474ab281eb207b4e3a553c
Autor:
Alex M. Pagnozzi, Nicholas Dowson, James Doecke, Simona Fiori, Andrew P. Bradley, Roslyn N. Boyd, Stephen Rose
Publikováno v:
NeuroImage: Clinical, Vol 11, Iss C, Pp 751-759 (2016)
White and grey matter lesions are the most prevalent type of injury observable in the Magnetic Resonance Images (MRIs) of children with cerebral palsy (CP). Previous studies investigating the impact of lesions in children with CP have been qualitativ
Externí odkaz:
https://doaj.org/article/2e5cc5db1c694e778b1d7650c2bf3fba
Autor:
Ishani Sahama, Kate Sinclair, Simona Fiori, James Doecke, Kerstin Pannek, Lee Reid, Martin Lavin, Stephen Rose
Publikováno v:
NeuroImage: Clinical, Vol 9, Iss C, Pp 206-215 (2015)
Background: Our understanding of the effect of ataxia–telangiectasia mutated gene mutations on brain structure and function is limited. In this study, white matter motor pathway integrity was investigated in ataxia telangiectasia patients using dif
Externí odkaz:
https://doaj.org/article/2fec4cd5b4c54587864623d8fc9dcde2
Autor:
Alex M Pagnozzi, Nicholas Dowson, James Doecke, Simona Fiori, Andrew P Bradley, Roslyn N Boyd, Stephen Rose
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181605 (2017)
Previous studies have proposed that the early elucidation of brain injury from structural Magnetic Resonance Images (sMRI) is critical for the clinical assessment of children with cerebral palsy (CP). Although distinct aetiologies, including cortical
Externí odkaz:
https://doaj.org/article/af24631f292d40028520b6fdc181182f
Autor:
Charisse N. Winston, Oliver Langford, Natalie Levin, Rema Raman, Kevin Yarasheski, Tim West, Sara Abdel-Latif, Michael Donohue, Akinori Nakamura, Kenji Toba, Colin L. Masters, James Doecke, Reisa A. Sperling, Paul S. Aisen, Robert A. Rissman
Publikováno v:
Journal of Alzheimer's Disease. 92:95-107
Background: Participant eligibility for the A4 Study was determined by amyloid PET imaging. Given the disadvantages of amyloid PET imaging in accessibility and cost, blood-based biomarkers may serve as a sufficient biomarker and more cost-effective s